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GABPB2


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Symbol:GABPB2
Name(s):GA binding protein transcription factor, beta subunit 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:BABPB2, E4TF1, E4TF1-47, E4TF1-53, E4TF1B, GABPB, GABPB1, NRF2B1, NRF2B2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17357964 Observational study of gene-disease association. (HuGE Navigator)
17726090 serum-responsive GABP binding to Ets-binding sites activates the KIS promoter, leading to KIS gene expression, cell migration, and cell cycle progression
16412436 Results point out that brain-specific angiogenesis inhibitor 2 controls VEGF transcription through GA-binding protein under normal conditions and cerebral ischemia [GA-binding protein gamma].
12016589 Mutation of a nuclear respiratory factor 2 binding site in the 5' untranslated region of the ADSL gene in three patients with adenylosuccinate lyase deficiency.
9461436 The cyrstal structure of a ternary complex containing the mouse GA binding protein transcription factor, beta subunit 2, was resolved at 2.15 angstrom resolution.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDActivating transcription factor 1GA binding protein transcription factor, beta subunit 2 isoform beta 1--Pubmed
HPRDGA binding protein transcription factor, alpha subunitGA binding protein transcription factor, beta subunit 2 isoform beta 1--Pubmed
HPRDGA binding protein transcription factor, alpha subunitGA binding protein transcription factor, beta subunit 2 isoform beta 1--Pubmed

Recent Publications on GABPB2:

Pubmed Logo
GABPbeta2 is dispensible for normal lymphocyte development but moderately affects B cell responses.
GA-binding protein (GABP) is the only Ets family transcription factor that...
22nd October, 2008
Department of Microbiology, Carver College of Medicine, University of J Biol Chem. 2008 Sep 5;283(36):24326-33. Epub 2008 Jul 15.
DOI Direct Link
Quantitative immuno-electron microscopic analysis of nuclear respiratory factor 2 alpha and beta subunits: Normal distribution and activity-dependent regulation in mammalian visual cortex.
The macaque visual cortex is exquisitely organized into columns, modules,...
3rd June, 2005
Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Vis Neurosci. 2005 Jan-Feb;22(1):1-18.
DOI Direct Link
Ultrastructural study of depolarization-induced translocation of NRF-2 transcription factor in cultured rat visual cortical neurons.
Nuclear respiratory factor (NRF)-2 or GA-binding protein is a potential...
7th May, 2004
Department of Cell Biology, Medical College of Wisconsin, 8701 Watertown Eur J Neurosci. 2004 Mar;19(5):1153-62.
DOI Direct Link
Depolarizing stimulation upregulates GA-binding protein in neurons: a transcription factor involved in the bigenomic expression of cytochrome oxidase subunits.
Neurons are unique in having dendrites that extend far away from their...
8th June, 2000
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Eur J Neurosci. 2000 Mar;12(3):1013-23.

Patents:

Patents logo
US Patent No.Title
7598031 Method for the detection of gene transcripts in blood and uses thereof
7381526 Assays for drug discovery based on microcompetition with a foreign polynucleotide
7235358 Methods and compositions for diagnosing and monitoring transplant rejection
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases

View more patents.

GABPB2 results (if any) from reagent suppliers

Google CSE Logo
GABPB2 antibodies: Chromatin and Nuclear Signaling > Transcription ...
GABPB2 antibodies. ... GABPB2 antibody [11]. WB, ELISA. Images. Mouse monoclonal . Reacts with: Hu. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=198622&pt=1&c=3579&ei=&mu=...

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GABP-β1/2 (J-25) Antibody sc-133605
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GABPB2, 2553, 15q21.2, Q06547 ...
http://www.scbt.com/datasheet-133605-gabp-beta1-2-j-25-antib...

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MB-MN
human ... GABPB2(126626), human, ELISA (i), WB, pricing. WH0084245M1, Monoclonal Anti-MGC3207 antibody produced in mouse, 2D11-1G4 (monoclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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GABP Antibody / GABP Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. GABP-α (352C3a) Antibody, sc-81277, mouse IgG1, Internal (h), WB, IP, human ...
http://www.scbt.com/ko/table-gabp.html...

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Abcam antibodies and reagents product map
... Cdk8 antibodies (4) · Cdk8 proteins and peptides (1) · Cyclin C proteins and peptides (2) · GABPB2 antibodies (2) · KAT13C / NCOA2 antibodies (10) ...
http://www.abcam.com/index.html?c=250...

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GABP-β1/2 (H-265) Antibody sc-28684
Human, GABPB2, 2553, 15q21.2, NM_002041, NM_005254, NM_016654, NM_016655, NM_181427 · Q06547 ... Mouse, Gabpb2, 213054, 3 F2.1, P81069 ...
http://www.scbt.com/ko/datasheet-28684-gabp-beta1-2-h-265-an...

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