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GABRA1


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Symbol:GABRA1
Name(s):gamma-aminobutyric acid (GABA) A receptor, alpha 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:ECA4, EJM
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18292428 Using wild type/mutated receptor subunits to identify compounds with anesthetic effect.
11140838 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12210273 Observational study of gene-disease association. (HuGE Navigator)
12232773 Observational study of gene-disease association. (HuGE Navigator)
12645817 Observational study of gene-disease association. (HuGE Navigator)
14631097 Observational study of gene-disease association. (HuGE Navigator)
14706423 Observational study of gene-disease association. (HuGE Navigator)
15542698 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15955415 Observational study of genotype prevalence. (HuGE Navigator)
16172613 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDDopamine receptor D4gamma-aminobutyric acid A receptor, alpha 1 precursor--Pubmed
HPRDdopamine receptor D4GABA-A receptor, alpha 1--Pubmed
HPRDgamma-aminobutyric acid A receptor, alpha 1 precursorProtein kinase C, gamma--Pubmed

Recent Publications on GABRA1:

Pubmed Logo
Advances on the genetics of mendelian idiopathic epilepsies.
Genetic factors play an increasingly recognized role in idiopathic...
27th October, 2009
UPMC/Inserm, UMR_S975, Cricm, F-75013, Batiment Pharmacie, Hopital de la Neurol Clin. 2009 Nov;27(4):1041-61.
DOI Direct Link
Neuroligin-2 accelerates GABAergic synapse maturation in cerebellar granule cells.
Neuroligins (NLGs) are postsynaptic cell adhesion molecules that are...
21st October, 2009
Department of Psychiatry, Box 3209, Duke University Medical Center, 401I Mol Cell Neurosci. 2009 Sep;42(1):45-55. Epub 2009 May 20.
DOI Direct Link
Brain regional distribution of GABA(A) receptors exhibiting atypical GABA agonism: roles of receptor subunits.
The major inhibitory neurotransmitter in the brain, gamma-aminobutyric...
10th October, 2009
Institute of Biomedicine, Pharmacology, Biomedicum Helsinki, University of Neurochem Int. 2009 Nov;55(6):389-96. Epub 2009 May 4.
DOI Direct Link
Changes in neuronal activity and gene expression in guinea-pig auditory brainstem after unilateral partial hearing loss.
Spontaneous neural hyperactivity in the central auditory pathway is often...
22nd September, 2009
Physiology, School of Biomedical, Biomolecular and Chemical Sciences, Neuroscience. 2009 Mar 31;159(3):1164-74. Epub 2009 Feb 12.
DOI Direct Link
Relation between increased anxiety and reduced expression of alpha1 and alpha2 subunits of GABA(A) receptors in Wfs1-deficient mice.
Mutations in the coding region of the WFS1 gene cause Wolfram syndrome, a...
3rd September, 2009
Department of Physiology, University of Tartu, 19 Ravila Street, 50411 Neurosci Lett. 2009 Aug 28;460(2):138-42. Epub 2009 May 27.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7599933 Coupled two-way clustering analysis of data
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7157569 Mutation associated with epilepsy

View more patents.

GABRA1 results (if any) from reagent suppliers

Google CSE Logo
Antibodies to GABA and Glycine Receptors
mouse ... Gabra1(14394) human ... GABRA1(2554) rat ... Gabra1(29705), rat, mouse , human (predicted), bovine (predicted), chicken (predicted) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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GABAA Rα1 (A-20) Antibody sc-31405
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GABRA1, 2554, 5q34, NM_000806 ...
http://www.scbt.com/datasheet-31405-gabaa-ralpha1-a-20-antib...

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G4416 Anti-GABAA Receptor (α1 subunit) antibody produced in rabbit ...
Gene Information, human ... GABRA1(2554). rat ... Gabra1(29705). mouse ... Gabra1(14394). storage temp. −20°C. Safety. WGK Germany, 2. References ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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GABA(A) Receptor Family
type A α1 subunit, GABRA1) Extracellular. Product #: AGA-001. Host: Rabbit. Epitope: Peptide (C)TPEPNKKPENKPA, corresponding to amino acid residues ...
http://www.alomone.com/system/UpLoadFiles/DGallery/Docs/gaba...

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ANTI-GABAA Receptor (alpha1 subunit) (G4416) - Data Sheet
Receptor type A α1 subunit, GABRA1) is produced in rabbit using as immunogen a highly purified peptide. QPSQDELKDNTTVFTR(C), corresponding to amino ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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Anti-GABA(A) α1 (extracellular)-ATTO-488
24 Sep 2009 ... (γ-aminobutyric acid receptor type A α1 subunit, GABRA1). Product #: AGA-001-AG. Current Lot #: AN-01. Host: Rabbit. Type: Polyclonal. ...
http://www.alomone.com/System/UpLoadFiles/DGallery/Docs/AGA-...

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GABAA Rα1 (N-19) Antibody sc-7348
Humano, GABRA1, 2554, 5q34, NM_000806 · P14867, n/a. camundongo, Gabra1, 14394, 11 A5, P62812, N/A. Informacoes sobre ordens ...
http://www.scbt.com/pt/datasheet-7348-gabaa-ralpha1-n-19-ant...

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