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GABRA4
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18334916 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16080114 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 16770606 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17135278 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16080114 |
GABRA4 is involved in the etiology of autism and potentially increases autism risk through interaction with GABRB1. |
| 12242096 |
truncated alpha 4 N-terminus may play a post-translational regulatory role in intracellular folding/glycosylation/assembly of the alpha 4 subunit |
| 16770606 |
These results confirmed our earlier findings, indicating GABRA4 and GABRB1 as genes contributing to autism susceptibility, extending the effect to multiple ethnic groups and suggesting seizures as a stratifying phenotype. |
| 17124266 |
alpha4beta3gamma2L receptors have unique kinetic properties that limit the range of GABA applications to which they can respond maximally. |
Recent Publications on GABRA4: |  |
Effects of the beta-amino acid antagonist TAG on thalamocortical inhibition.
Chemical transmission at inhibitory synapses in thalamus may involve... | 29th August, 2009
| Department of Anesthesiology, Pharmacology and Therapeutics, University of
| Neuropharmacology. 2009 Jun;56(8):1097-105. Epub 2009 Mar 28.
DOI Direct Link |
Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerstrom Test for Nicotine Dependence.
AIMS: A previous association analysis identified polymorphisms in... | 16th May, 2009
| Department of Psychiatry, Washington University School of Medicine, St.
| Addiction. 2009 Mar;104(3):471-7.
DOI Direct Link |
Alpha4-containing GABAA receptors in the nucleus accumbens mediate moderate intake of alcohol.
Alcohol has subjective and behavioral effects at the pharmacological... | 9th April, 2009
| Ernest Gallo Clinic and Research Center, University of California, San
| J Neurosci. 2009 Jan 14;29(2):543-9.
DOI Direct Link |
Strong genetic evidence for a selective influence of GABA(A) receptors on a component of the bipolar disorder phenotype.
Despite compelling evidence for a major genetic contribution to risk of... | 17th December, 2008
| 1Department of Psychological Medicine, School of Medicine, Cardiff
| Mol Psychiatry. 2008 Jul 1.
DOI Direct Link |
Variation in GABA-A subunit gene copy number in an autistic patient with mosaic 4 p duplication (p12p16).
Autism has been associated with chromosomal aberrations, including... | 17th December, 2008
| Department of Pediatrics, Kanazawa Medical University, Ishikawa, Japan.
| Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5;147B(6):973-5.
DOI Direct Link |
→View more research publications. |
GABRA4 results (if any) from reagent suppliers | 
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Antibodies to GABA and Glycine Receptors
G0170, Anti-GABAA Receptor (α4 subunit), N-Terminus antibody produced in rabbit, (polyclonal), affinity isolated antibody, rat ... Gabra4(140675) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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GABAA Rα4 (H-160) Antibody sc-20917
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GABRA4, 2557, 4p12, NM_000809 ...
http://www.scbt.com/datasheet-20917-gabaa-ralpha4-h-160-anti...
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A2129 γ-Aminobutyric acid GABA ≥99%
GABBR1(2550), GABBR2(9568), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4( 2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=A212...
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Egr-3 (C-24) Antibody sc-191
Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABA(A) receptor alpha4 subunit expression. ...
http://www.scbt.com/datasheet-191-egr-3-c-24-antibody.html...
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V8261 Vigabatrin
GABBR1(2550), GABBR2(9568), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4( 2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562) ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=V826...
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GABAA Rα4 siRNA (m) sc-35434
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Gabra4, 14397, 5 C3.2, Q9D6F4 ...
http://www.scbt.com/datasheet-35434-gabaa-ralpha4-sirna-m.ht...
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C4024 Carbamazepine powder
BZRAP1(9256), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5( 2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), PRNP(5621), ...
https://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=C40...
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