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GABRB2


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Symbol:GABRB2
Name(s):gamma-aminobutyric acid (GABA) A receptor, beta 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC119386, MGC119388, MGC119389
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18334916 Observational study of gene-disease association. (HuGE Navigator)
11140951 Observational study of gene-disease association. (HuGE Navigator)
12232773 Observational study of gene-disease association. (HuGE Navigator)
15542698 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16172613 Observational study of gene-disease association. (HuGE Navigator)
16472798 Observational study of gene-disease association. (HuGE Navigator)
16766085 Observational study of gene-disease association. (HuGE Navigator)
16778401 Observational study of gene-disease association. (HuGE Navigator)
16950232 Observational study of gene-disease association. (HuGE Navigator)
17167345 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDGamma aminobutyric acid receptor, beta 25-hydroxytryptamine receptor 1A--Pubmed
HPRDgamma-aminobutyric acid A receptor, beta 2 isoform 15-hydroxytryptamine receptor, 1A--Pubmed
HPRDgamma-aminobutyric acid A receptor, beta 2 isoform 1trafficking protein, kinesin binding 2--Pubmed
HPRDgamma-aminobutyric acid A receptor, beta 2 isoform 1trafficking protein, kinesin binding 2--Pubmed

Recent Publications on GABRB2:

Pubmed Logo
Homology modeling of human alpha 1 beta 2 gamma 2 and house fly beta 3 GABA receptor channels and Surflex-docking of fipronil.
To further explore the mechanism of selective binding of the...
14th October, 2009
School of Chemical Engineering & Pharmacy, Key Laboratory for Green J Mol Model. 2009 Sep;15(9):1145-53. Epub 2009 Feb 24.
DOI Direct Link
Brain regional distribution of GABA(A) receptors exhibiting atypical GABA agonism: roles of receptor subunits.
The major inhibitory neurotransmitter in the brain, gamma-aminobutyric...
10th October, 2009
Institute of Biomedicine, Pharmacology, Biomedicum Helsinki, University of Neurochem Int. 2009 Nov;55(6):389-96. Epub 2009 May 4.
DOI Direct Link
Predicting the effect of naltrexone and acamprosate in alcohol-dependent patients using genetic indicators.
Acamprosate and naltrexone are effective medications in the treatment of...
25th September, 2009
Amsterdam Institute for Addiction Research, Academic Medical Center, Addict Biol. 2009 Jul;14(3):328-37.
DOI Direct Link
Alternative-splicing in the exon-10 region of GABA(A) receptor beta(2) subunit gene: relationships between novel isoforms and psychotic disorders.
BACKGROUND: Non-coding single nucleotide polymorphisms (SNPs) in GABRB2,...
19th September, 2009
Department of Biochemistry and Applied Genomics Center, Fok Ying Tung PLoS One. 2009 Sep 18;4(9):e6977.
DOI Direct Link
Altering the relative abundance of GABA A receptor subunits changes GABA- and ethanol-responses in Xenopus oocytes.
BACKGROUND: Variations in GABRA2 and GABRG3, genes encoding the alpha2 and...
8th September, 2009
Department of Biochemistry and Molecular Biology, Indiana University Alcohol Clin Exp Res. 2009 Jun;33(6):1089-96. Epub 2009 Mar 23.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7365163 GABA.sub.A receptor epsilon subunits
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7157569 Mutation associated with epilepsy

View more patents.

GABRB2 results (if any) from reagent suppliers

Google CSE Logo
GABAA Rβ2 (J-21) Antibody sc-133601
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GABRB2, 2561, 5q34, P47870 ...
http://www.scbt.com/datasheet-133601-gabaa-rbeta2-j-21-antib...

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Antibodies to GABA and Glycine Receptors
G9544, Anti-GABAA Receptor (β2 subunit), Cytosolic Loop antibody produced in rabbit, (polyclonal), affinity isolated antibody, rat ... Gabrb2(25451) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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GABAA Rβ2 (S-19) Antibody sc-31428
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, GABRB2, 2561, 5q34, NM_000813, NM_021911 ...
http://www.scbt.com/de/datasheet-31428-gabaa-rbeta2-s-19-ant...

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A2129 γ-Aminobutyric acid GABA ≥99%
GABBR1(2550), GABBR2(9568), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4( 2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=A212...

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GABAA Rβ1 (N-19) Antibody sc-7361
Mouse, Gabrb2, 14401, 11 A5, P63137, N/A. Ordering Information. Product Name, Catalog #, Unit, Price, Qty, Wish List. GABAA Rβ1 (N-19), sc-7361, 200 µg/ml ...
http://www.scbt.com/datasheet-7361-gabaa-rbeta1-n-19-antibod...

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Pathway Diagrams: PI3K / Akt Substrates
GABRB2, S434, 12818177, ligand gated chloride ion channel; phosphorylation increases synaptic transmission. GATA-1, S310, 16107690, transcription factor;
...
http://www.cellsignal.com/reference/pathway/akt_substrates.h...

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GABAA Rβ1/2/3 (H-50) Antibody sc-28794
Mouse, Gabrb2, 14401, 11 A5, P63137, N/A. Mouse, Gabrb3, 14402, 7 C, P63080, N/A . Ordering Information. Product Name, Catalog #, Unit, Price, Qty, Wish List ...
http://www.scbt.com/datasheet-28794-gabaa-rbeta1-2-3-h-50-an...

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