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GABRG2


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Symbol:GABRG2
Name(s):gamma-aminobutyric acid (GABA) A receptor, gamma 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:CAE2, ECA2, GEFSP3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18085588 In the SNr GABA(A) receptors contain alpha(1), alpha(3), beta(2,3), and gamma(2) subunits and are localized in a weblike network over the cell soma, dendrites, and spines of SNr parvalbumin-positive nonpigmented neurons.
18292428 Using wild type/mutated receptor subunits to identify compounds with anesthetic effect.
11140951 Observational study of gene-disease association. (HuGE Navigator)
12117362 Observational study of gene-disease association. (HuGE Navigator)
12232773 Observational study of gene-disease association. (HuGE Navigator)
12672902 Observational study of gene-disease association. (HuGE Navigator)
12694927 Observational study of gene-disease association. (HuGE Navigator)
12759178 Observational study of gene-disease association. (HuGE Navigator)
15542698 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15772696 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDdopamine receptor D5gamma-aminobutyric acid A receptor, gamma 2 precursor--Pubmed
HPRDdopamine receptor D5gamma-aminobutyric acid A receptor, gamma 2 precursor--Pubmed
HPRDgamma-aminobutyric acid A receptor, gamma 2 precursorGABA(A) receptor-associated protein--Pubmed
HPRDgamma-aminobutyric acid A receptor, gamma 2 precursorGABA(A) receptor-associated protein--Pubmed

Recent Publications on GABRG2:

Pubmed Logo
Advances on the genetics of mendelian idiopathic epilepsies.
Genetic factors play an increasingly recognized role in idiopathic...
27th October, 2009
UPMC/Inserm, UMR_S975, Cricm, F-75013, Batiment Pharmacie, Hopital de la Neurol Clin. 2009 Nov;27(4):1041-61.
DOI Direct Link
Association study between GABA receptor genes and anxiety spectrum disorders.
Background: Human anxiety disorders are complex diseases with relatively...
21st October, 2009
Department of Psychiatry, Virginia Institute for Psychiatric and Depress Anxiety. 2009 Oct 19;26(11):998-1003.
DOI Direct Link
Mutational analysis of the SCN1A, SCN1B and GABRG2 genes in 150 Italian patients with idiopathic childhood epilepsies.
The gamma-aminobutyrate type A receptor-associated protein (GABARAP) is a...
6th October, 2009
Clin Genet. 2009 Jun;75(6):579-81.
Missense mutation of the sodium channel gene SCN2A causes Dravet syndrome.
Mutations of the gene encoding the alpha2 subunit of the neuronal sodium...
29th September, 2009
Department of Pediatrics, School of Medicine, Fukuoka University, Fukuoka Brain Dev. 2009 Nov;31(10):758-62. Epub 2009 Sep 23.
DOI Direct Link
Structure and potential function of gamma-aminobutyrate type A receptor-associated protein.
The gamma-aminobutyrate type A receptor-associated protein (GABARAP) is a...
16th September, 2009
Institut fur Strukturbiologie und Biophysik (ISB-3), Forschungszentrum FEBS J. 2009 Sep;276(18):4989-5005. Epub 2009 Aug 6.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Cohorts and Collections: Clinical and Genetic Study of Parkinson's Disease and Epilepsies

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7282336 Method of diagnosing epilepsy
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7157569 Mutation associated with epilepsy

View more patents.

GABRG2 results (if any) from reagent suppliers

Google CSE Logo
Antibodies to GABA and Glycine Receptors
G9919, Anti-GABAA Receptor (γ2 subunit), Cytosolic Loop antibody produced in rabbit, (polyclonal), affinity isolated antibody, rat ... Gabrg2(29709) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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GABAA Rγ2 (Q-18) Antibody sc-101963
Human, GABRG2, 2566, 5q34, NM_000816, NM_198903, NM_198904 · P18507 · 611277. Mouse, 4406, N/A. Mouse, Gabrg2, 14406, 11 A5, P22723 ...
http://www.scbt.com/datasheet-101963-gabaa-rgamma2-q-18-anti...

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GODZ antibody (ab31837) | Abcam
GODZ is a palmitoyl acyl transferase with broad specificity. GODZ palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and ...
http://www.abcam.com/GODZ-antibody-ab31837.html...

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p-GABAA Rγ2 (Ser 365) Antibody sc-135693
Species, Nome del gene, Codice del gene, Locus cromosoma, Isoform (mRNA) Accession #, codice accesso proteina, Numero d' ordine. Human, GABRG2, 2566,
5q34 ...
http://www.scbt.com/it/datasheet-135693-p-gabaa-rgamma2-ser-...

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Synaptic Inhibition in Health and Disease conferen ... | Abcam
A mutation of GABRG2 linked to generalized epilepsy with febrile seizures alters the membrane dynamics of GABA receptors; Bernhard Luscher (Penn State ...
http://www.abcam.com/go.cfm?p=2763...

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p-GABAA Rγ2 (Ser 365) Antibody sc-135693
Humano, GABRG2, 2566, 5q34, P18507 · 611277. camundongo, Gabrg2, 14406, 11 A5, P22723, N/A. Informacoes sobre ordens. Nome do Produto, Numero de Catalogo ...
http://www.scbt.com/pt/datasheet-135693-p-gabaa-rgamma2-ser-...

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BIOMOL International - GABA Receptor Antibodies
Anti-GABAA Receptor Gamma2, C-terminus Loop (GABRG2) · Privacy Policy Buy online or call 1-800-942-0430 Designed by NetReach. BIOMOL International LP ©2006 ...
http://www.biomol.com/?pageId=36&categoryId=983...

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