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GABRR1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18227272 |
Results imply that the M3M4 loop is not essential for GABA rho1 receptor assembly and function and suggest that the cytoplasmic domain may fold as an independent module from the transmembrane and extracellular domains. |
| 18079559 |
Charge selectivity of the anionic rho1 GABA receptor can be influenced by the introduction of glutamates, one at a time, over an 8-amino acid stretch (-2' to 5') in the proposed intracellular end of TM2 and the TM1-TM2 intracellular linker. |
| 15548535 |
a complete model of the GABA(C) receptor binding pocket was proposed and discussed in comparison with the GABA(A) receptor binding pocket |
| 12226075 |
Tyr-102 is a component of the GABA binding domain and it might be important for coupling agonist binding to channel opening |
| 15163459 |
a single amino acid change within the ion-channel domain of the gamma-aminobutyric acid rho1 receptor accelerates desensitization and increases taurine agonism |
| 16198491 |
GABA receptor subunit rho-1 effectively altered gene expression through its interaction with the cellular retinoic acid binding protein pathway |
| 11862606 |
examination of receptor modulation by divalent cations |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Gamma aminobutyric acid receptor, rho 1 | microtubule-associated protein 1B isoform 1 | - | - | Pubmed |
| HPRD | Gamma aminobutyric acid receptor, rho 1 | purinergic receptor P2X2 isoform D | - | - | Pubmed |
| HPRD | gamma-aminobutyric acid receptor, rho 1 | Microtubule associated protein 1B | - | - | Pubmed |
| HPRD | gamma-aminobutyric acid receptor, rho 1 | Solute carrier family 6 member 9 | - | - | Pubmed |
| HPRD | gamma-aminobutyric acid receptor, rho 1 | Solute carrier family 39, member 3 | - | - | Pubmed |
| HPRD | gamma-aminobutyric acid receptor, rho 1 | Purinergic receptor P2X ligand gated ion channel 2 | - | - | Pubmed |
| HPRD | gamma-aminobutyric acid receptor, rho 1 | gamma-aminobutyric acid receptor, rho 2 precursor | - | - | Pubmed |
| HPRD | gamma-aminobutyric acid receptor, rho 1 | gamma-aminobutyric acid receptor, rho 2 precursor | - | - | Pubmed |
Recent Publications on GABRR1: |  |
GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence.
The genes encoding several GABA-A receptor subunits, including GABRA2,... | 19th June, 2009
| Department of Biochemistry and Molecular Biology, Indiana University
| Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 17.
DOI Direct Link |
Strong genetic evidence for a selective influence of GABA(A) receptors on a component of the bipolar disorder phenotype.
Despite compelling evidence for a major genetic contribution to risk of... | 17th December, 2008
| 1Department of Psychological Medicine, School of Medicine, Cardiff
| Mol Psychiatry. 2008 Jul 1.
DOI Direct Link |
Structural determinants for antagonist pharmacology that distinguish the rho1 GABAC receptor from GABAA receptors.
GABA receptor (GABAR) types C (GABACR) and A (GABAAR) are both GABA-gated... | 28th October, 2008
| Division of Neurobiology, Barrow Neurological Institute, 350 West Thomas
| Mol Pharmacol. 2008 Oct;74(4):941-51. Epub 2008 Jul 3.
DOI Direct Link |
GABAC-receptor stimulation activates cAMP-dependent protein kinase via A-kinase anchoring protein 220.
In our previous study, anti-apoptotic effects of GABA(C)-receptor... | 25th July, 2008
| Department of Pharmacology, Kansai Medical University, Moriguchi, Osaka,
| J Pharmacol Sci. 2008 Apr;106(4):578-84. Epub 2008 Apr 3.
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Expression of GABArho subunits during rat cerebellum development.
In the present study, we provide evidence for the expression of all three... | 25th April, 2008
| Instituto de Neurobiologia, Departamento de Neurobiologia Molecular y
| Neurosci Lett. 2008 Feb 13;432(1):1-6. Epub 2007 Dec 14.
DOI Direct Link |
→View more research publications. |
GABRR1 results (if any) from reagent suppliers |
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GABAA Rρ1 (V-17) Antibody sc-22960
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GABRR1, 2569, 6q15, NM_002042 ...
http://www.scbt.com/datasheet-22960-gabaa-rrho1-v-17-antibod...
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Anti-GABAA Receptor (γ2 subunit), Cytosolic Loop Developed in ...
2 (GABRR2) and rho-1 (GABRR1) to human and mouse chromosome 4. Genomics, 12, 801 -806. (1992). 4. Jones, A., et al., Ligand-gated ion channel subunit ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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GABA Receptor Antibody / GABA Receptor Antibodies
GABA Receptor Antibody / GABA Receptor Antibodies.
http://www.scbt.com/table-gaba_receptor.html...
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GABAA Rρ1 (H-70) Antibody sc-25707
Humano, GABRR1, 2569, 6q15, NM_002042 · P24046 · 137161. camundongo, Gabrr1, 14408, 4 A5, P56475, N/A. Informacoes sobre ordens ...
http://www.scbt.com/pt/datasheet-25707-gabaa-rrho1-h-70-anti...
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GABAA Rρ1 (N-19) Antibody sc-21336
Species, Nome del gene, Codice del gene, Locus cromosoma, Isoform (mRNA) Accession #, codice accesso proteina, Numero d' ordine. Human, GABRR1, 2569, 6q15 ...
http://www.scbt.com/it/datasheet-21336-gabaa-rrho1-n-19-anti...
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GABAA Rρ1 (H-70) Antibody sc-25707
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, GABRR1, 2569, 6q15, NM_002042 · P24046 ...
http://www.scbt.com/ja/datasheet-25707-gabaa-rrho1-h-70-anti...
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