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GAD1


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Gene DB Home
Symbol:GAD1
Name(s):glutamate decarboxylase 1 (brain, 67kDa)
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ45882, GAD, SCP
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18294085 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18335162 Observational study of gene-disease association. (HuGE Navigator)
11140838 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
14681921 Observational study of gene-disease association. (HuGE Navigator)
15091314 Observational study of gene-disease association. (HuGE Navigator)
15103710 Observational study of gene-disease association. (HuGE Navigator)
15806582 Observational study of gene-disease association. (HuGE Navigator)
16718280 Observational study of gene-disease association. (HuGE Navigator)
17412563 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17767149 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDGlutamate decarboxylase 1glutamate decarboxylase 2--Pubmed
HPRDglutamate decarboxylase 1 isoform GAD67Glutamate decarboxylase 2--Pubmed

Recent Publications on GAD1:

Pubmed Logo
Influence of 17beta-estradiol and progesterone on GABAergic gene expression in the arcuate nucleus, amygdala and hippocampus of the rhesus macaque.
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in...
17th October, 2009
Division of Neuroscience, Oregon National Primate Research Center, 505 NW Brain Res. 2009 Oct 13.
DOI Direct Link
Changes in neuronal activity and gene expression in guinea-pig auditory brainstem after unilateral partial hearing loss.
Spontaneous neural hyperactivity in the central auditory pathway is often...
22nd September, 2009
Physiology, School of Biomedical, Biomolecular and Chemical Sciences, Neuroscience. 2009 Mar 31;159(3):1164-74. Epub 2009 Feb 12.
DOI Direct Link
A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase.
Glutamate decarboxylase (Gad) catalyzes glutamate to gamma-aminobutyrate...
15th September, 2009
Biochemisches Institut, Universitat Zurich, Zurich, Switzerland. J Mol Biol. 2009 Sep 18;392(2):334-51. Epub 2009 Jul 4.
DOI Direct Link
Some molecular effectors of antidepressant action of quetiapine revealed by DNA microarray in the frontal cortex of anhedonic rats.
OBJECTIVES AND METHODS: We have previously demonstrated that quetiapine...
12th September, 2009
Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Pharmacogenet Genomics. 2009 Aug;19(8):600-12.
DOI Direct Link
Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry.
Genomic studies demonstrate that, although the majority of the mammalian...
10th September, 2009
Developmental Biology and Department of Pediatrics, Children's Memorial Nat Neurosci. 2009 Aug;12(8):1020-7. Epub 2009 Jul 20.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Varenicline for Cigarette Smoking in Schizophrenia - Efficacy and Predictors

Patents:

Patents logo
US Patent No.Title
5200318 Diagnosis of IDDM with a panel of immunoreagents
6165738 Expression in yeast of antigenically active, recombinant hybrid glutamic acid decarboxylase
6184353 Method for modulating processes mediated by farnesoid activated receptors
6210950 Methods for diagnosing, preventing, and treating developmental disorders due to a combination of genetic and environmental factors
6211352 Method for the diagnosis and treatment of glutamic acid decarboxylase autoantigen associated diseases

View more patents.

GAD1 results (if any) from reagent suppliers

Google CSE Logo
GAD67 Antibody GAD1 (isoform GAD67)
GAD67 antibody was raised against a synthetic peptide of GAD67.,
http://www.prosci-inc.com/shop/catalog1/GAD67-Antibody-p-276...

Thumbshot
Human GAD1/GAD67 Affinity Purified Polyclonal Ab
specific IgG was purified by human GAD1 affinity chromatography. ... This antibody has been selected for its ability to recognize human GAD1 in the ...
http://www.rndsystems.com/pdf/AF2086.pdf...

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GAD
Polyclonal rabbit antibody 1 against GAD 1 / GAD 67. Cat. No. 198 003 ... Specificity, Specific for GAD 1. Polyclonal rabbit antibody 2 against GAD 1 /
GAD ...
http://www.sysy.com/products/gad/facts.php...

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Human GAD1/GAD67 Biotinylated Affinity Purified PAb
GAD1/GAD67 specific IgG was purified by human GAD1/GAD67 affinity ... appropriate secondary reagents to detect human GAD1/GAD67. The detection ...
http://www.rndsystems.com/pdf/BAF2086.pdf...

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Human GAD1 ChIP Primer and Probe Set (ab85780) | Abcam
ChIP Primer Pair and Probe for GAD1. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in ...
http://www.abcam.com/Human-GAD1-ChIP-Primer-and-Probe-Set-ab...

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Immunohistochemistry : GAD1/GAD67 - R&D Systems
This antibody specifically recognizes human GAD1. This antibody has not yet been tested in other species. This antibody can be used for immunohistochemistry ...
http://www.rndsystems.com/ihc_molecule_images.aspx?m=1480...

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GAD1 dna rna and cdna: Signal Transduction > Metabolism > Amino ...
GAD1 dna rna and cdna. ... GAD1 dna rna and cdna. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication ...
http://www.abcam.com/index.html?t=287793&pt=10&c=712&ei=&mu=...

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