Wednesday November 25 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

GAD2


Suggest Content
Advertise Here
Gene DB Home
Symbol:GAD2
Name(s):glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Type:protein-coding
Organism:Homo sapiens
Synonyms:GAD65, MGC161605, MGC161607
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17167787 We found glutamic acid decarboxylase (Gad65)antibodies in idiopathic generalized epilepsy and type 1 diabetes.
17412563 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17459095 Observational study of gene-disease association. (HuGE Navigator)
14691540 Observational study of gene-disease association. (HuGE Navigator)
15091314 Observational study of gene-disease association. (HuGE Navigator)
15642443 Observational study of gene-disease association. (HuGE Navigator)
15671113 Observational study of gene-disease association. (HuGE Navigator)
16122350 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
16718280 Observational study of gene-disease association. (HuGE Navigator)
16741266 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDGlutamate decarboxylase 1glutamate decarboxylase 2--Pubmed
HPRDglutamate decarboxylase 1 isoform GAD67Glutamate decarboxylase 2--Pubmed
HPRDglutamate decarboxylase 2protein kinase C, epsilon--Pubmed
BINDglutamate decarboxylase 2huntingtin interacting protein 14HIP14 catalyzes palmitoylation of GAD65. This interaction was modeled on a demonstrated interaction between human HIP14 and GAD65 from an unspecified species.-Pubmed

Recent Publications on GAD2:

Pubmed Logo
Influence of 17beta-estradiol and progesterone on GABAergic gene expression in the arcuate nucleus, amygdala and hippocampus of the rhesus macaque.
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in...
17th October, 2009
Division of Neuroscience, Oregon National Primate Research Center, 505 NW Brain Res. 2009 Oct 13.
DOI Direct Link
DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma.
High-throughput microarray technologies were used to study DNA methylation...
3rd October, 2009
Department of Pathology and Anatomical Sciences, University of Genes Chromosomes Cancer. 2009 Sep;48(9):828-41.
DOI Direct Link
Relation between increased anxiety and reduced expression of alpha1 and alpha2 subunits of GABA(A) receptors in Wfs1-deficient mice.
Mutations in the coding region of the WFS1 gene cause Wolfram syndrome, a...
3rd September, 2009
Department of Physiology, University of Tartu, 19 Ravila Street, 50411 Neurosci Lett. 2009 Aug 28;460(2):138-42. Epub 2009 May 27.
DOI Direct Link
GAD2 gene sequence variations are associated with eating behaviors and weight gain in women from the Quebec family study.
The glutamate decarboxylase 2 (GAD2) gene encodes for the glutamic acid...
19th August, 2009
Division of kinesiology, Department of Social and Preventive Medicine, Physiol Behav. 2009 Oct 19;98(4):505-10. Epub 2009 Aug 15.
DOI Direct Link
The gad2 promoter is a transcriptional target of estrogen receptor (ER)alpha and ER beta: a unifying hypothesis to explain diverse effects of estradiol.
Estradiol (E(2)) regulates a wide range of neural functions, many of which...
4th August, 2009
Department of Biology, University of Massachusetts Amherst, Amherst, J Neurosci. 2009 Jul 8;29(27):8790-7.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7592423 Globular adiponectin variants
6841718 Transgenic plants incorporating traits of Zostera marina
6727411 Method of producing transgenic plants having improved amino acid composition
6706867 DNA array sequence selection
6689589 Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids

View more patents.

GAD2 results (if any) from reagent suppliers

Google CSE Logo
GAD2 Antibody #3988
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide (KLH-coupled) surrounding Ala150 of human GAD2. Antibodies are purified
by ...
http://www.cellsignal.com/products/3988.html...

Thumbshot
Antibodies to Neural Enzymes
human ... GAD2(2572), human, pig, rat, mouse, monkey, ARR, IHC (p), WB, pricing ... GAD2(2572), mammals (and some lower vertebrates), IHC, WB, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

Thumbshot
GAD2/GAD65 - R&D Systems
Two forms, GAD1/GAD67 and GAD2/GAD65, have been identified in human. ... GAD2/ GAD65 is an autoimmune target in insulin-dependent diabetes mellitus. ...
http://www.rndsystems.com/molecule_detail.aspx?m=2501...

Thumbshot
GAD
Polyclonal rabbit antibody against GAD 2 / GAD 65. Cat. No. 198 102 ... Immunogen, Purified recombinant mouse GAD 2 (aa 3 - 96). ...
http://www.sysy.com/products/gad/facts.php...

Thumbshot
G5163 Anti-Glutamic Acid Decarboxylase 65/67 antibody produced in ...
microarray: suitable. Gene Information, human ... GAD2(2572). rat ... Gad2(24380 ). mouse ... Gad2(14417). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=G516...

Thumbshot
SNAP25 (D110) Antibody #3926
3835 GABA(B)R1 Antibody · 3839 GABA(B)R2 Antibody · 3988 GAD2 Antibody · 3757 SNIP/p140Cap Antibody · 2869 Syntaxin 6 (C34B2) Rabbit mAb ...
http://www.cellsignal.com/products/3926.html...

Thumbshot
GAD-65 (H-95) Antibody sc-5601
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GAD2, 2572, 10p12.1, NM_000818 ...
http://www.scbt.com/datasheet-5601-gad-65-h-95-antibody.html...

Thumbshot

Search Bioportfolio and other Life Science Sites for GAD2, or search for GAD2 on BioPortfolio's antibody search engine.
This page has been viewed 119 times
Recent Search Terms used to find this page:
GAD2 antibody | glutamate GAD2 anxiety | the GAD2 | GAD2 protein | GAD2 methylation | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.