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GAPDH


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Symbol:GAPDH
Name(s):glyceraldehyde-3-phosphate dehydrogenase
Type:protein-coding
Organism:Homo sapiens
Synonyms:G3PD, GAPD, MGC88685
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18340469 Observational study of gene-disease association. (HuGE Navigator)
15507493 Observational study of gene-disease association. (HuGE Navigator)
17989880 These results suggest that the polyQ domain, but not the polyP domain, plays a role in the sequestration of GAPDH to aggregates by mutant htt
17540725 Nitric oxide-mediated S-nitrosylation of GAPDH and subsequent nuclear translocation of GAPDH might function as a mediator of TRAIL-induced cell death in thyroid cancer cells.
17553795 Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells
15985219 evidence that GAPDH is an epithelial binding receptor for Porphyromonas gingivalis fimbriae
17121833 GAPDH interacts with transferrin and the GAPDH-transferrin complex is subsequently internalized into the early endosomes.
15485821 data suggest that glyceraldehyde-3-phosphate dehydrogenase (GAPDH) imparts a unique function necessary for membrane trafficking from vesicular tubular clusters (VTCs) that does not require GAPDH glycolytic activity
14630908 nuclear GAPDH has a role in the maintenance and/or protection of telomeres
12842822 Transcription factors bound to glutamine-responsive element in GAPDH promoter are C/EBPalpha and -delta.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDamyloid beta A4 protein precursor, isoform aglyceraldehyde-3-phosphate dehydrogenase--Pubmed
HPRDamyloid beta A4 protein precursor, isoform aglyceraldehyde-3-phosphate dehydrogenase--Pubmed
HPRDAndrogen receptorglyceraldehyde-3-phosphate dehydrogenase--Pubmed
HPRDandrogen receptor isoform 1Glyceraldehyde 3 phosphate dehydrogenase--Pubmed
HPRD2,3-bisphosphoglycerate mutaseglyceraldehyde-3-phosphate dehydrogenase--Pubmed
HPRD2,3-bisphosphoglycerate mutaseglyceraldehyde-3-phosphate dehydrogenase--Pubmed
HPRDGlyceraldehyde 3 phosphate dehydrogenaseS100A6 protein--Pubmed
HPRDGlyceraldehyde 3 phosphate dehydrogenaseataxin 1--Pubmed
HPRDGlyceraldehyde 3 phosphate dehydrogenaseglutamate receptor, metabotropic 1--Pubmed
HPRDGlyceraldehyde 3 phosphate dehydrogenasephospholipase D2--Pubmed

Recent Publications on GAPDH:

Pubmed Logo
A prototype nonpeptidyl, hydrazone class, thrombopoietin receptor agonist, SB-559457, is toxic to primary human myeloid leukemia cells.
Biologic characterization of SB-559457 (SB), a non-peptidyl hydrazone...
3rd November, 2009
Division of Hematology/Oncology, Department of Medicine, University of Blood. 2009 Oct 30.
DOI Direct Link
Evaluation of real-time PCR endogenous control genes for analysis of gene expression in bovine endometrium.
ABSTRACT: BACKGROUND: Quantitative real-time PCR gene expression results...
3rd November, 2009
BMC Mol Biol. 2009 Nov 1;10(1):100.
DOI Direct Link
A critical role of plastidial glycolytic glyceraldehyde-3-phosphate dehydrogenase in the control of plant metabolism and development.
Glycolysis is a central metabolic pathway that provides energy and...
31st October, 2009
Departament de Biologia Vegetal, Facultat de Farmacia, Universitat de Plant Signal Behav. 2010 Jan 29;5(1).
Glyceraldehyde 3 phosphate dehydrogenase in retinal microvasculature: Implications for the development and progression of diabetic retinopathy.
Objective: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been...
31st October, 2009
Ophthalmology, Wayne State University, Detroit, United States. Invest Ophthalmol Vis Sci. 2009 Oct 29.
DOI Direct Link
An aggregate-prone mutant of human glyceraldehyde-3-phosphate dehydrogenase augments oxidative stress-induced cell death in SH-SY5Y cells.
Glycerladehyde-3-phosphate dehydrogenase (GAPDH), a classic glycolytic...
31st October, 2009
Laboratory of Veterinary Pharmacology, Graduate School of Life and Biochem Biophys Res Commun. 2009 Oct 27.
DOI Direct Link

View more research publications.

BioNews Results for GAPDH

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Santhera Receives Grant from Association Franaise contre les Myopathies for its Omigapil Program in Congenit
Pharma Live:  Nov 5 2009 11:15PM Matching: gapdh
The evaluation of putative endogenous control housekeeping genes for real-time polymerase chain reaction expre
DiagnosticMicrobiology and Infectious Disease:  Oct 12 2009 9:11PM Matching: gapdh

Patents:

Patents logo
US Patent No.Title
7601508 Whitefly ecdysone receptor polypeptide and methods
7604947 Detection and modulation of cancer stem cells
7604992 Generation of neural stem cells from undifferentiated human embryonic stem cells
7605126 Acylaminoheteroaryl hepatitis C virus protease inhibitors
7605140 Regulation of angiogenesis with zinc finger proteins

View more patents.

GAPDH results (if any) from reagent suppliers

Google CSE Logo
GAPDH monoclonal antibody (ab9484) | Abcam
Our new mouse monoclonal antibody to GAPDH joins our existing range of GAPDH loading control antibodies, which includes our goat polyclonal to GAPDH ...
http://www.abcam.com/index.html?pageconfig=resource&rid=340&...

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GAPDH Antibody / GAPDH Antibodies
GAPDH Antibody / GAPDH Antibodies. ... GAPDH specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-gapdh.html...

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The Abcam catalog
GAPDH antibodies. ... GAPDH antibody. Flow Cyt, WB, ELISA, ICC/IF, IP ... GAPDH antibody [mAbcam 9484] (HRP) - Loading Control ...
http://www.abcam.com/index.html?t=6613&pt=1&c=587...

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Monoclonal Antibody to GAPDH - Loading Control
Protein loading control, protein normalization, housekeeping protein, protein standardization, GAPDH-loading control, glyceraldehyde 3-phosphate ...
http://www.imgenex.com/antibody_details.php?catalog=IMG-5019...

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GAPDH antibody (ab9485) | Abcam
See below for GAPDH antibody images, references, products related to ab9485 and other tools. ... Contact Abcam with a Technical Enquiry about GAPDH antibody ...
http://www.abcam.com/GAPDH-antibody-ab9485.html...

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G9545 Anti-GAPDH antibody produced in rabbit ~1 mg/mL, affinity ...
G9545 Anti-GAPDH antibody produced in rabbit ~1mg/mL, affinity isolated antibody , buffered aqueous solution.
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=G954...

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Purified Anti-GAPDH Antibody - BioLegend
Purified Anti-GAPDH Antibody - This rabbit polyclonal antibody recognizes human, mouse, rat, and rabbit GAPDH also known as glyceraldehyde-3-phosphate ...
http://www.biolegend.com/purified-anti-gapdh-antibody-4063.h...

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