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GAPDH


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Symbol:GAPDH
Name(s):glyceraldehyde-3-phosphate dehydrogenase
Type:protein-coding
Organism:Homo sapiens
Synonyms:G3PD, GAPD, MGC88685
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18340469 Observational study of gene-disease association. (HuGE Navigator)
15507493 Observational study of gene-disease association. (HuGE Navigator)
17989880 These results suggest that the polyQ domain, but not the polyP domain, plays a role in the sequestration of GAPDH to aggregates by mutant htt
17540725 Nitric oxide-mediated S-nitrosylation of GAPDH and subsequent nuclear translocation of GAPDH might function as a mediator of TRAIL-induced cell death in thyroid cancer cells.
17553795 Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells
15985219 evidence that GAPDH is an epithelial binding receptor for Porphyromonas gingivalis fimbriae
17121833 GAPDH interacts with transferrin and the GAPDH-transferrin complex is subsequently internalized into the early endosomes.
15485821 data suggest that glyceraldehyde-3-phosphate dehydrogenase (GAPDH) imparts a unique function necessary for membrane trafficking from vesicular tubular clusters (VTCs) that does not require GAPDH glycolytic activity
14630908 nuclear GAPDH has a role in the maintenance and/or protection of telomeres
12842822 Transcription factors bound to glutamine-responsive element in GAPDH promoter are C/EBPalpha and -delta.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDamyloid beta A4 protein precursor, isoform aglyceraldehyde-3-phosphate dehydrogenase--Pubmed
HPRDamyloid beta A4 protein precursor, isoform aglyceraldehyde-3-phosphate dehydrogenase--Pubmed
HPRDAndrogen receptorglyceraldehyde-3-phosphate dehydrogenase--Pubmed
HPRDandrogen receptor isoform 1Glyceraldehyde 3 phosphate dehydrogenase--Pubmed
HPRD2,3-bisphosphoglycerate mutaseglyceraldehyde-3-phosphate dehydrogenase--Pubmed
HPRD2,3-bisphosphoglycerate mutaseglyceraldehyde-3-phosphate dehydrogenase--Pubmed
HPRDGlyceraldehyde 3 phosphate dehydrogenaseS100A6 protein--Pubmed
HPRDGlyceraldehyde 3 phosphate dehydrogenaseataxin 1--Pubmed
HPRDGlyceraldehyde 3 phosphate dehydrogenaseglutamate receptor, metabotropic 1--Pubmed
HPRDGlyceraldehyde 3 phosphate dehydrogenasephospholipase D2--Pubmed

Recent Publications on GAPDH:

Pubmed Logo
Digital quantification of gene expression using emulsion PCR.
Here we describe a single-molecule quantitative assay of mRNA levels based...
2nd February, 2010
State Key Laboratory of Bioelectronics, Southeast University, Nanjing, P. Electrophoresis. 2010 Jan;31(3):528-34.
DOI Direct Link
[Clinical application of SYBR Green I real-time fluorescence quantitative PCR for diagnosis of common chromosome aneuploidy.]
OBJECTIVE: To investigate the value of real-time fluorescence quantitative...
2nd February, 2010
Basic Medical Experiment Teaching Center, School of Basic Medical Nan Fang Yi Ke Da Xue Xue Bao. 2010 Jan;30(1):11-5.
Dynamin-1 co-associates with native mouse brain BK(Ca) channels: Proteomics analysis of synaptic protein complexes.
In every synapse, a large number of proteins interact with other proteins...
2nd February, 2010
Waggoner Center for Alcohol and Addiction Research, College of Natural FEBS Lett. 2010 Jan 28.
DOI Direct Link
Normalization with genes encoding ribosomal proteins but not GAPDH provides an accurate quantification of gene expressions in neuronal differentiation of PC12 cells.
ABSTRACT: BACKGROUND: Gene regulation at transcript level can provide a...
2nd February, 2010
BMC Genomics. 2010 Jan 29;11(1):75.
DOI Direct Link
Differential proteomic response to heat stress in thermal Agrostis scabra and heat-sensitive Agrostis stolonifera.
Knowledge of heat-responsive proteins is critical for further...
2nd February, 2010
Department of Plant Biology and Pathology, Rutgers University, New Physiol Plant. 2010 Jan 25.
DOI Direct Link

View more research publications.

BioNews Results for GAPDH

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Novel roles for GAPDH in cell death and carcinogenesis FREE
Nature:  Dec 8 2009 7:13PM Matching: gapdh

Patents:

Patents logo
US Patent No.Title
7638272 Cancer therapy sensitizer
7638621 siRNA targeting insulin-like growth factor 1 receptor (IGF-1R)
7638622 SiRNA targeting intercellular adhesion molecule 1 (ICAM1)
7641897 Feeder layer and serum independent embryonic stem cells
7641905 Methods of inducing an immune response

View more patents.

GAPDH results from Abnova

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Sponsored Results:

Abnova Logo
GAPDH monoclonal antibody, clone 1D4
Mouse monoclonal antibody raised against GAPDH.
Symbol: GAPDH  Alias: GAPD
http://www.abnova.com/products/products_detail.asp?catalog_id=MAB2319
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Abnova Logo
GAPDH Recombinant Protein (P01)
GAPDH( AAH09081, 1 a.a. - 336 a.a.) full-length recombinant protein with GST tag.
Symbol: GAPDH  Alias: G3PD, GAPD, MGC88685
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002597-P01
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Abnova Logo
GAPDH Pre-design Chimera RNAi
Homo sapiens glyceraldehyde-3-phosphate dehydrogenase (GAPDH), mRNA
Symbol: GAPDH  Alias: G3PD; GAPD; MGC88685
http://www.abnova.com/products/products_detail.asp?catalog_id=R0016
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Abnova Logo
GAPDH monoclonal antibody, clone 6F7
Mouse monoclonal antibody raised against GAPDH.
Symbol: GAPDH
http://www.abnova.com/products/products_detail.asp?catalog_id=MAB2783
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Abnova Logo
GAPDH purified MaxPab mouse polyclonal antibody (B01P)
Mouse polyclonal antibody raised against a full-length human GAPDH protein.
Symbol: GAPDH  Alias: G3PD, GAPD, MGC88685
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002597-B01P
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Abnova Logo
GAPDH Pre-design Chimera RNAi
Homo sapiens glyceraldehyde-3-phosphate dehydrogenase (GAPDH), mRNA.
Symbol: GAPDH  Alias: G3PD, GAPD, MGC88685
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002597-R01
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Search for GAPDH products at Abnova.

GAPDH results (if any) from reagent suppliers

Google CSE Logo
GAPDH monoclonal antibody (ab9484) | Abcam
Our new mouse monoclonal antibody to GAPDH joins our existing range of GAPDH loading control antibodies, which includes our goat polyclonal to GAPDH ...
http://www.abcam.com/index.html?pageconfig=resource&rid=340&...

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GAPDH Antibody / GAPDH Antibodies
GAPDH Antibody / GAPDH Antibodies. ... GAPDH specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-gapdh.html...

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The Abcam catalog
GAPDH antibody [mAbcam 9484] (HRP) - Loading Control. WB. Images · Customer Abreviews: 3 stars (out of 5) · Specific publication references ...
http://www.abcam.com/index.html?t=6613&pt=1&c=587...

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Monoclonal Antibody to GAPDH - Loading Control
Protein loading control, protein normalization, housekeeping protein, protein standardization, GAPDH-loading control, glyceraldehyde 3-phosphate ...
http://www.imgenex.com/antibody_details.php?catalog=IMG-5019...

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GAPDH antibody (ab9485) | Abcam
See below for GAPDH antibody images, references, products related to ab9485 and other tools. ... Contact Abcam with a Technical Enquiry about GAPDH antibody ...
http://www.abcam.com/GAPDH-antibody-ab9485.html...

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G9545 Anti-GAPDH antibody produced in rabbit ~1 mg/mL, affinity ...
2: Antibody 0.1 μg/mL + GAPDH immunizing peptide (mouse 314-333) ... Immunogen, synthetic peptide corresponding to amino acids 314-333 of mouse GAPDH, ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=G954...

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Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) antibody
monoclonal mouse anti-rabbit glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
http://www.hytest.fi/product/glyceraldehyde-3-phosphate-dehy...

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