Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18340469 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15507493 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17989880 |
These results suggest that the polyQ domain, but not the polyP domain, plays a role in the sequestration of GAPDH to aggregates by mutant htt |
| 17540725 |
Nitric oxide-mediated S-nitrosylation of GAPDH and subsequent nuclear translocation of GAPDH might function as a mediator of TRAIL-induced cell death in thyroid cancer cells. |
| 17553795 |
Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells |
| 15985219 |
evidence that GAPDH is an epithelial binding receptor for Porphyromonas gingivalis fimbriae |
| 17121833 |
GAPDH interacts with transferrin and the GAPDH-transferrin complex is subsequently internalized into the early endosomes. |
| 15485821 |
data suggest that glyceraldehyde-3-phosphate dehydrogenase (GAPDH) imparts a unique function necessary for membrane trafficking from vesicular tubular clusters (VTCs) that does not require GAPDH glycolytic activity |
| 14630908 |
nuclear GAPDH has a role in the maintenance and/or protection of telomeres |
| 12842822 |
Transcription factors bound to glutamine-responsive element in GAPDH promoter are C/EBPalpha and -delta. |
| 17597534 |
Study observed no hypoxia-induced regulation of GAPDH expression in the 3 glioblastoma cell lines; also, GAPDH expression was similar in patient tumor samples of low-grade astrocytoma and glioblastoma, suggesting a lack of hypoxic regulation in vivo. |
| 12008025 |
We identified a nuclear high molecular weight (HMW) GAPDH species in Huntington's disease cells, suggesting a connection between nuclear GAPDH function and huntingtin localization in this CAG expansion neuronal disease. |
| 12921788 |
Glycoaldehyde inactivates GAPD. |
| 16778134 |
OxLDL downregulated GAPDH via a H2O2-dependent decrease in protein stability. GAPDH protein damage resulted in marked depletion of cellular ATP levels. |
| 16832079 |
The GAPD gene and its pseudogene may play a role in the development of late-onset Alzheimer disease. However, the effect, if any, is likely to be limited. |
| 17027006 |
identified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a new interacting partner of TPPP/p25 within the alpha-synuclein positive Lewy body |
| 16037232 |
Conditions associated with elevated intracellular methylglyoxal could modify GAPDH activity in vivo. |
| 16186172 |
Amyloid-beta induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease |
| 12428732 |
GAPDH may be involved in the cellular phenotype of age-related neurodegenerative disorders--REVIEW |
| 17387692 |
alpha-crystallin B, glyceraldehyde phosphate dehydrogenase (GAPDH), and alpha-enolase identified as significantly S-glutathionylated in Alzheimer's disease infeior parietal lobule |
| 16082386 |
GAPDH is an integral part of the sarcolemmal K(ATP)-channel protein complex, where it couples glycolysis with the K(ATP)-channel activity. |
| 17324518 |
A decrease in the dehydrogenase activity of GAPDH was noted in Alzheimer disease. |
| 14730345 |
Thioredoxin regulates the expression of GAPDH. |
| 12121569 |
GAPDH is not an ideal internal standard for specific gene expression in testicular tissue specimens |
| 12697324 |
HIF-2alpha regulates glyceraldehyde-3-phosphate dehydrogenase gene expression in vascular endothelial cells. |
| 15769908 |
Marked variability of GAPDH expression between tissue types which establish comparative levels of expression and can be used to add value to gene expression data in which GAPDH is used as the internal control. |
| 16139273 |
Data show that the insertion of ferriprotoporphyrin IX (FP) into the red cell membranes exerts two opposite effects on membrane bound G3PD. |
| 16515701 |
GAPDH is inaccurate to normalize mRNA levels in studies investigating the effect of bisphosphonates on gene expression; this gene could be considered a potential target to observe the effects of bisphosphonates on cancer cells |
| 15507493 |
significant association between late-onset Alzheimer's disease and a compound genotype of the three GAPD genes |
| 15907785 |
GAPDH modified by 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal is degraded by a giant serine protease, releasing the 23-kDa fragment, not by proteasome or TPP I |
| 15716040 |
Subcellular interactions may mitigate oxidative stress-induced GAPDH modification in human aging. |
| 12503091 |
dissociation of the GAPDH protein from the HMW species restores its enzymatic activity. |
| 15746184 |
results demonstrate that glyceraldehyde-3-phosphate dehydrogenase, a glycolytic and microtubule binding protein, co-localized to neurofibrillary tangles and immunoprecipitated with paired helical filament-tau |
| 16474839 |
GAPDH might be involved in cell cycle regulation by modulating cyclin B-cdk1 activity. |
| 17015754 |
TPI and GAPDH may be candidate Ags for an autoimmune response to neurons and axons in multiple sclerosis. |
| 14515148 |
Glyceraldehyde-3-phosphate dehydrogenase might be a novel target for vaccinia anti-apoptotic modulation. |
| 15001839 |
GAPDH mRNA expression was correlated with evidence of tumor progression in thymoma. |
| 12887926 |
The p38/gapdh component of OCA-S binds directly to OCT1. |
