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GATA1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18206727 |
Altered SDF-1/CXCR4 axis in patients with primary myelofibrosis and in the Gata1 low mouse model of the disease |
| 12816863 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15136229 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 17576817 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 17763153 |
findings support the concept that GATA-1 platelets are macrothrombocytes because they are not able to detach normally from each other during separation from megakaryocyte proplatelets |
| 17881640 |
disorder derived from GATA1 Arg216Gln mutation is X-linked thrombocytopenia with thalassemia |
| 17576817 |
GATA1 mutation is associated with Down syndrome related acute megakaryoblastic leukemia |
| 17654061 |
There was no difference in the expression level of GATA-1 gene in the bone marrow stromal cells between normal controls and chronic aplastic anemia group. |
| 16840187 |
GATA-1 may have a role in Down syndrome leukemogenesis [review] |
| 12196550 |
with NF-E2, mediates expression of alpha-spectrin gene promoter in erythroid cells in vitro | →View more information from publications. |
Recent Publications on GATA1: |  |
Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome.
Down syndrome (DS) children have a unique genetic susceptibility to... | 29th October, 2009
| Department of Nutrition and Food Science, Wayne State University, Detroit,
| Blood. 2009 Sep 24;114(13):2753-63. Epub 2009 Jul 24.
DOI Direct Link |
Loss of the Gata1 gene IE exon leads to variant transcript expression and the production of a GATA1 protein lacking the N-terminal domain.
GATA1 is essential for the differentiation of erythroid cells and... | 27th October, 2009
| Tohoku University, Japan;
| J Biol Chem. 2009 Oct 23.
DOI Direct Link |
LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis.
GATA-1-dependent transcription is essential for erythroid differentiation... | 27th October, 2009
| Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial
| Dev Cell. 2009 Oct;17(4):527-40.
DOI Direct Link |
New GATA1 mutation in codon 2 leads to the earliest known premature stop codon in transient myeloproliferative disorder.
GATA-1-dependent transcription is essential for erythroid differentiation... | 24th October, 2009
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| Blood. 2009 Oct 22;114(17):3717-8.
DOI Direct Link |
Removal of the spleen in mice alters the cytokine expression profile of the marrow micro-environment and increases bone formation.
Splenectomized mice express progressively increased numbers of platelets... | 24th October, 2009
| Department of Hematology, Oncology, and Molecular Medicine, Istituto
| Ann N Y Acad Sci. 2009 Sep;1176:77-86.
DOI Direct Link |
→View more research publications. |
GATA1 results (if any) from reagent suppliers | 
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