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GATA3


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Symbol:GATA3
Name(s):GATA binding protein 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:HDR, MGC2346, MGC5199, MGC5445
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18079734 Direct interactions between NKX2-5 and GATA3 as indicated by co-immunoprecipitation data may contribute to MEF2C regulation.
18037162 Gene-gene interaction between GATA3 and IL13 polymorphisms can influence the risk of childhood rhinitis.
15637551 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
18006915 Observational study of gene-disease association. (HuGE Navigator)
18037162 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17845581 Transactivation by GATA-3 increased luciferase expression 100-fold, in the absence of stimulation. Synergistic interactions were demonstrated between Ets1, GATA-3 and AP-1.
18154704 Role in the proliferaative and regenerative capacity of mammary stem and progenitor cells.
18212358 The expression patterns of T-Bet and GATA-3 oppose progesterone receptor, suggesting antagonistic function and/or regulation between PR and T-Bet/GATA-3
17654061 GATA-3 expression in bone marrow stromal cells from chronic aplastic anemia was significantly higher than controls. Expression levels of GATA genes may influence hematopoiesis in BM microenvironment & relate to the pathogenesis/development of AA.
17658279 Gata3 is a critical element determining inductive T helper (Th) type 2 cell differentiation and limiting Th1 differentiation by Notch.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDETS1GATA binding protein 3 isoform 2--Pubmed
HPRDv-ets erythroblastosis virus E26 oncogene homolog 1GATA binding protein 3--Pubmed
HPRDETS2GATA binding protein 3 isoform 2--Pubmed
HPRDv-ets erythroblastosis virus E26 oncogene homolog 2GATA binding protein 3--Pubmed
HPRDGATA binding protein 3LIM domain only 2--Pubmed
HPRDGATA binding protein 3 isoform 2LIM domain only 2--Pubmed
HPRDGATA binding protein 3 isoform 2LIM domain only 1--Pubmed
HPRDGATA binding protein 3 isoform 2LIM domain only 1--Pubmed

Recent Publications on GATA3:

Pubmed Logo
Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life.
In the adult mouse, distinct morphological and transcriptional differences...
31st October, 2009
Department of Cell and Developmental Biology, University of Michigan, Ann Dev Dyn. 2009 Oct 29.
DOI Direct Link
GATA3 is a master regulator of the transcriptional response to low-dose ionizing radiation in human keratinocytes.
BACKGROUND: The general population is constantly exposed to low levels of...
31st October, 2009
Universite BMC Genomics. 2009 Sep 7;10:417.
DOI Direct Link
GATA factors in human neuroblastoma: distinctive expression patterns in clinical subtypes.
BACKGROUND: The aim of this study is to elucidate the expression patterns...
29th October, 2009
Department of Neonatology, Charite-Universitatsmedizin Berlin, Berlin, Br J Cancer. 2009 Oct 20;101(8):1481-9. Epub 2009 Aug 25.
DOI Direct Link
Identification of functionally related genes using data mining and data integration: a breast cancer case study.
BACKGROUND : The identification of the organisation and dynamics of...
27th October, 2009
Istituto Tecnologie Biomediche, Consiglio Nazionale Ricerche, Via Fratelli BMC Bioinformatics. 2009 Oct 15;10 Suppl 12:S8.
DOI Direct Link
Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease.
Allergic asthma is an inflammatory disease of the lung characterized by...
22nd October, 2009
Immunology and Respiratory Research Group, John Hunter Children's Proc Natl Acad Sci U S A. 2009 Oct 20.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Biomarkers in Predicting Response to Tamoxifen and Letrozole in Postmenopausal Women With Primary Breast Cancer Treated on Clinical Trial CAN-NCIC-MA17

Patents:

Patents logo
US Patent No.Title
7612181 Dual variable domain immunoglobulin and uses thereof
7358041 Antibodies to magmas and uses thereof
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7195870 Diagnosis of diseases associated with gene regulation
7171311 Methods of assigning treatment to breast cancer patients

View more patents.

GATA3 results (if any) from reagent suppliers

Google CSE Logo
GATA3 antibody (ab32858) | Abcam
Rabbit polyclonal to GATA3. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers ...
http://www.abcam.com/GATA3-antibody-ab32858.html...

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GATA-3 (D-16) Antibody sc-22206
See how others have used GATA-3 (D-16): sc-22206 antibody and or GATA-3 ... Western blot analysis of GATA-3 expression in non-transfected: sc-110760 (A) and
...
http://www.scbt.com/datasheet-22206-gata-3-d-16-antibody.htm...

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mouse/human Gata-3 antibody, Alexa Fluor® 647 conjugate
eBioscience technical data sheet for product 51-9966 Alexa Fluor® 647 anti-mouse /human Gata-3 (Gata3) TWAJ antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_51/51-...

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Purified Anti-GATA 3 Antibody - BioLegend
Purified Anti-GATA 3 Antibody - GATA3 is a 45-50 kD transcription factor found in the nucleus of T cells, mast cells, and embryonic brain and kidney that ...
http://www.biolegend.com/purified-anti-gata-3-antibody-2076....

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GATA Antibody / GATA Antibodies
GATA-3 (B-10) Antibody, sc-137152, mouse IgG1, C-terminal (h), WB, IP, ... GATA- 3 (1A10D1) Antibody, sc-130057, mouse IgG1, 175-388 (h), WB, ELISA, human ...
http://www.scbt.com/table-gata.html...

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mouse/human Gata-3 antibody, Affinity Purified conjugate
eBioscience technical data sheet for product 14-9966 Affinity Purified anti- mouse/human Gata-3 (Gata3) TWAJ antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_14/14-...

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GATA-3 (HG3-31) Antibody sc-268
See how others have used GATA-3 (HG3-31): sc-268 antibody and or GATA-3 ... GATA -3 (HG3-31) X TransCruz antibody is recommended for Gel Supershift and ChIP ...
http://www.scbt.com/datasheet-268-gata-3-hg3-31-antibody.htm...

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