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FGF21
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17926232 |
work suggests a potential role for Fibroplast growth factor 21(FGF-21) in the pathogenesis of insulin resistance and type 2 diabetes mellitus (T2DM) |
| 17452648 |
klotho beta functions as a cofactor essential for FGF21 activity |
| 17068132 |
When administered daily for 6 wk to diabetic rhesus monkeys, FGF-21 caused a dramatic decline in fasting plasma glucose, fructosamine, triglycerides, insulin, and glucagon. |
Recent Publications on FGF21: |  |
Torpor induction in mammals: recent discoveries fueling new ideas.
When faced with a harsh climate or inadequate food, some mammals enter a... | 30th October, 2009
| Department of Biology, University of Minnesota Duluth, 1035 Kirby Drive,
| Trends Endocrinol Metab. 2009 Oct 26.
DOI Direct Link |
Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes.
Fibroblast growth factor 21 (FGF21) has beneficial effects of improving... | 23rd October, 2009
| Department of Diabetes and Endocrinology, Gifu University, Graduate School
| FEBS Lett. 2009 Sep 3;583(17):2882-6. Epub 2009 Aug 4.
DOI Direct Link |
Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver.
Fibroblast growth factors (Fgfs) are polypeptide growth factors with... | 23rd October, 2009
| Department of Genetic Biochemistry, Kyoto University Graduate School of
| Endocrinology. 2009 Oct;150(10):4625-33. Epub 2009 Jul 9.
DOI Direct Link |
Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity.
OBJECTIVE: Fibroblast growth factor-21 (FGF21) is a novel endocrine and... | 20th October, 2009
| Third Department of Medicine, First Faculty of Medicine and General
| Clin Endocrinol (Oxf). 2009 Sep;71(3):369-75. Epub 2008 Dec 11.
DOI Direct Link |
Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis.
Fibroblast growth factor 21 (FGF21) is a key metabolic regulator.... | 13th October, 2009
| Associate Professor of Medicine, Division of Endocrinology, Diabetes, and
| Endocrinology. 2009 Nov;150(11):4931-40. Epub 2009 Oct 9.
DOI Direct Link |
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