|
| |
HSPB8
| Symbol: | HSPB8 | | Name(s): | heat shock 22kDa protein 8 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
|
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18229450 |
Hsp22 induction represents a new aspect of the estrogenic response with potential significance for the biology of estrogen receptor-positive breast cancer cells. |
| 18094623 |
HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy. |
| 18006506 |
These results suggested that the HspB8-Bag3 complex might stimulate the degradation of Htt43Q by macroautophagy. |
| 17922839 |
Effect of mutations in the beta5-beta7 loop on the structure and properties of human small heat shock protein HSP22 |
| 18006821 |
HSPB8 is a candidate CDK-independent cyclin D1 target that can mediate its effects |
| 17304582 |
Displays chaperone activity, autokinase activity, and trigger or block apoptosis activity. Decrease may contribute to development of some neurologic diseases and others. (Review) |
| 16485107 |
HspB8 might play important role in regulating Abeta aggregation and, therefore, development of classic senile plaques in Alzheimer's disease and cerebral amyloid angiopathy in hereditary cerebral hemorrhage with amyloidosis of Dutch type. |
| 15541337 |
Hsp22 is highly homologous to small heat shock proteins and effectively prevents aggregation of denatured protein both in vitro and in vivo. It is supposed that chaperone-like activity is of great importance for Hsp22 functioning |
| 17173073 |
HspB8 overload causes melanoma growth arrest and apoptosis through TAK1 activation |
| 12832417 |
Forced H11 expression triggers apoptosis. | →View more information from publications. |
Recent Publications on HSPB8: |  |
The pivotal role of the beta7 strand in the intersubunit contacts of different human small heat shock proteins.
Human alphaB-crystallin and small heat shock proteins HspB6 and HspB8 were... | 27th October, 2009
| Department of Biochemistry, School of Biology, Moscow State University,
| Cell Stress Chaperones. 2009 Oct 24.
DOI Direct Link |
Identification of the key structural motifs involved in HspB8/HspB6-Bag3 interaction.
The molecular chaperone HspB8 is member of the B group of heat shock... | 23rd October, 2009
|
| Biochem J. 2009 Oct 21.
DOI Direct Link |
The HSV-2 mutant DeltaPK induces melanoma oncolysis through nonredundant death programs and associated with autophagy and pyroptosis proteins.
Malignant melanoma is a highly aggressive and drug-resistant cancer.... | 3rd October, 2009
| Department of Pharmacology and Experimental Therapeutics, University of
| Gene Ther. 2009 Oct 1.
DOI Direct Link |
The stress-inducible HspB8-Bag3 complex induces the eIF2alpha kinase pathway: implications for protein quality control and viral factory degradation?
The recently discovered HspB8-Bag3 complex participates in protein quality... | 10th September, 2009
| Department of Radiation and Stress Cell Biology, University Medical Center
| Autophagy. 2009 Apr;5(3):428-9. Epub 2009 Apr 21.
|
Autosomal dominant spastic paraplegia with peripheral neuropathy maps to chr12q23-24.
OBJECTIVE: Hereditary spastic paraplegias (HSP) are genetically... | 15th July, 2009
| Department of Neurology, University of Tubingen, Tubingen, Germany.
| Neurology. 2009 Jun 2;72(22):1893-8. Epub 2009 Apr 8.
DOI Direct Link |
→View more research publications. |
HSPB8 results (if any) from reagent suppliers | 
|
HSPB8/HSP22 Antibody
HSPs (sHSPs), HSPB8 is predominantly transcribed in skel- etal muscle and heart (1). ... Specificity/Sensitivity: HSPB8/HSP22 Antibody detects ...
http://www.cellsignal.com/pdf/3059.pdf...
|
 |
αC-crystallin (2H5) Antibody sc-51745
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, HSPB8, 26353, 12q24.23, NM_014365 ...
http://www.scbt.com/datasheet-51745-alphac-crystallin-2h5-an...
|
 |
HSPB8/HSP22 Antibody #3059
HSPB8 (HSP22) is a member of the small heat shock protein superfamily and the human protein is most closely related to HSP27. Similar to most other small ...
http://www.cellsignal.com/products/3059.html...
|
 |
Antibody Products - IgG Polyclonal Antibodies - GenWay
HSPB8; CRYAC; E2IG1; HSP22 - Heat shock 22kDa protein 8; N/A, IgG Polyclonal E, WB, Source: Goat Reactivity: Human. 0.1 mg ($255). 18-272-195372, H2A.X ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=H...
|
 |
Protein Folding and Stability
New 3059 HSPB8/HSP22 Antibody. 2404 Phospho-HSP27 (Ser15) Antibody. 2405 Phospho -HSP27 (Ser78) Antibody. 2401 Phospho-HSP27 (Ser82) Antibody ...
http://www.cellsignal.com/about/marketing/pdfs/protein_1008....
|
 |
Abgent - Neurosciences Antibodies
AP7139a, Hsp22 (HSPB8) Antibody (N-term), WB, E, H. AP1325a, Humanin Antibody, E , H. AP6118a, Huntingtin Associated Protein 1 (HAP1) antibody, E, H ...
http://www.abgent.com/products/category/neurosciences...
|
 |
Product Pathways: Protein Folding/Stability
4874 · HSP90 Antibody, W IHC-P, H M R Mk Dm (C) (B) (Z). 3488 · Phospho-HSP90α ( Thr5/7) Antibody, W, H M R Mk. 3059 · HSPB8/HSP22 Antibody, W, H M R Mk ...
http://www.cellsignal.com/pathways/protein-folding-stability...
|
 |
Search Bioportfolio and other Life Science Sites for HSPB8,
or search for HSPB8 on BioPortfolio's antibody search engine.
This page has been viewed 389 times
Recent Search Terms used to find this page: Homo sapiens heat shock 22kDa protein 8 HSPB8 | Homo sapiens heat shock 22kDa protein 8 HSPB8 | Heat shock protein HSPB8 | HspB8 Bag3 | small heat shock proteins 2009 | heat shock protein 8 | HSPB8 | Autophagy. 2009 Jan 1 5 1 120-1. Epub 2009 Jan 31. Links | heat shock protein 22KDa | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
