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LATS2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15688006 |
Mst2, a STE20-family member and purported Hpo ortholog, phosphorylates and activates both Lats1 and Lats2 |
| 17049657 |
LATS1 and LATS2 mRNA was down-regulated in astrocytoma by hypermethylation of the promoter |
| 15147269 |
S83 of Lats2 is a phosphorylation target of Aurora-A and this phosphorylation plays a role of the centrosomal localization of Lats2 |
| 15131260 |
LATS2 may play a role in androgen receptor-mediated transcription and contribute to the development of prostate cancer |
| 15746036 |
Hypermethylation of the promoter region of LATS2 likely plays an important role in the down-regulation of LATS2 mRNA level in breast cancers, and breast cancers with a decreased expression of LATS2 mRNA level have a biologically aggressive phenotype. |
| 15265683 |
Lats2 induces apoptosis through downregulating anti-apoptotic proteins, BCL-2 and BCL-x(L), in human lung cancer cells. |
| 12853976 |
of mammalian Lats2 and Lats1 control cell proliferation by negatively regulating different cell cycle check points. |
Recent Publications on LATS2: |  |
Frequent promoter hypermethylation of tumor-related genes in head and neck squamous cell carcinoma.
Squamous cell carcinomas of head and neck (HNSCC) are a result of multiple... | 4th November, 2009
| Institute for Genetics, Justus-Liebig University Giessen, Giessen,
| Oncol Rep. 2009 Dec;22(6):1519-1526.
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Mst Out and HCC In.
Mst1 and Mst2 are key components of the Hippo tumor suppressor pathway. In... | 3rd November, 2009
| Department of Pharmacology and Moores Cancer Center, University of
| Cancer Cell. 2009 Nov 6;16(5):363-4.
DOI Direct Link |
Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation.
The Lats2 tumor suppressor protein has been implicated earlier in... | 27th October, 2009
| Department of Molecular Cell Biology, The Weizmann Institute of Science,
| Oncogene. 2009 Oct 26.
DOI Direct Link |
Comparative expression of zebrafish lats1 and lats2 and their implication in gastrulation movements.
Large tumor suppressor (Lats) is a Ser/Thr kinase, and it presents an... | 21st October, 2009
| Department of Genetics and Center for Developmental Biology, College of
| Dev Dyn. 2009 Nov;238(11):2850-9.
DOI Direct Link |
Identification of LATS transcriptional targets in HeLa cells using whole human genome oligonucleotide microarray.
Human LATS1 and LATS2) (LATS1/2) are tumor suppressors that have been... | 6th October, 2009
| Department of Pathology and Molecular Medicine, Queen's University,
| Gene. 2010 Jan 1;449(1-2):22-29. Epub 2009 Sep 30.
DOI Direct Link |
→View more research publications. |
LATS2 results (if any) from reagent suppliers | 
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LATS2 antibody [mAbcam54073] (ab54073)
Mouse monoclonal [mAbcam54073] to LATS2. LATS2 is a tumor suppressor which plays a critical role in centrosome duplication, maintenance of mitotic fidelity ...
http://www.abcam.com/LATS2-antibody-mAbcam54073-ab54073.html...
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LATS2 Antibody Bethyl Laboratories
LATS2 (Large Tumor Suppressor homolog 2) has been identified as a tumor suppressor protein and is a member of the Dbf2-related (NDR) family of protein
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http://www.bethyl.com/product/A300-479A/LATS2_Antibody/AAAAA...
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LATS2 antibodies: Chromatin and Nuclear Signaling > DNA / RNA ...
LATS2 antibodies. ... LATS2 antibody. IHC-P, WB, IHC-Fr. Rabbit polyclonal. Reacts with: Hu, Ms. ab54073 · LATS2 antibody [mAbcam54073] ...
http://www.abcam.com/index.html?t=146962&pt=1&c=889&ei=&mu=r...
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Rabbit anti-LATS-1 (WARTS) Antibody BL2212, affinity purified
R anti-LATS2 Antibody BL2213. A300-479A. G anti-Rabbit IgG-h+l FITC conjugated A120-101F. G anti-Rabbit IgG-h+l HRP conjugated A120-101P ...
http://www.natutec.de/pdf_bethyl/A300-478A.pdf...
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kpm (K-17) Antibody sc-23065
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, LATS2, 26524, 13q12.11, NM_014572 ...
http://www.scbt.com/datasheet-23065-kpm-k-17-antibody.html...
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Abgent - Cell and Structure Antibodies - Cell_structure
AT2673a, LASP1 monoclonal antibody (M05), ELISA,WB-Tr, H. AP7035c, LATS2 Antibody (Center), WB, IHC, E, H, M. AP1801c, LC3 Antibody (APG8a) (I31), WB,
IHC, ...
http://www.abgent.com/products/category/cell_function/cell_s...
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kpm (K-17) Antibody sc-23065
种属, 基因名称, 基因ID, 染色质位置, 亚型（mRNA）即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, LATS2, 26524, 13q12.11, NM_014572 · Q9NRM7 ...
http://www.scbt.com/zh/datasheet-23065-kpm-k-17-antibody.htm...
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