Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17652002 |
Modest elevation of GGT observed in overweight children may be of pathophysiological importance in the long term |
| 17698237 |
Association between the serum level parameters of adiposity and lipid profile. |
| 17965490 |
Serum GGT may be an additional marker of arterial stiffness, especially in men, though the relationship with arterial stiffness was very weak. |
| 17895524 |
The results indicate that "silent" apoptosemia occurs in T1 and T2 diabetic children and suggest elevated GGT in diabetic children could be due to release from apoptotic cells |
| 12835487 |
The gamma-glutamyl transpeptidase activity in both oligoasthenospermic and azoospermic subjects were significantly lower than in asthenospermic and oligospermic individuals |
| 15528049 |
Membrane GGT activity-often expressed at high levels in human malignancies-can oxidize extracellular AA and promote its uptake efficiently. |
| 17503391 |
GGT1 is a biological tumor marker for epithelial ovarian cancers. |
| 17095717 |
An increase in serum GGT predicts onset of metabolic syndrome, incident CVD, and death suggesting that GGT is a marker of metabolic and cardiovascular risk. |
| 17109502 |
The biliary IL-6 and TNF-alpha levels were positively correlated with serum DBIL, TBA and gamma-GT levels in infantile hepatitis syndrome subjects. |
| 12532447 |
Gamma-glutamyl transpeptidase gene expression in liver, liver disease, and liver neoplasms. |
| 17260973 |
In contrast to the E Coli GGT1, in the human enzyme, a specific residue in the Cys-Gly binding site played a critical role in recognizing the Cys-Gly moiety or the acceptor molecules by interacting with the C-terminal carboxy group |
| 14754911 |
there is a complete deficiency of LTD(4) biosynthesis in patients with a genetic deficiency of GGT which represents a new inborn error of cysteinyl leukotriene synthesis |
| 15052692 |
Metabolic syndrome seemed to be directly, not indirectly through fatty liver, associated with the raised GGT level in Japanese women. No significant association between the raised GGT level and the presence of fatty liver. |
| 17141888 |
The role of high gammaGT activity in HepG2 cells can be connected with production of reactive oxygen species and with S-thiolation with Cys and Cys-Gly that can influence activity of caspase 3. |
| 11940314 |
explore the relationship between the alteration in gamma-glutamyl transpeptidase (GGT) mRNA expression and the development of hepatocellular carcinoma (HCC) |
| 12447480 |
Malignant lung tumors (squamous cell carcinoma and adenocarcinoma) had significantly increased levels of this enzyme. |
| 12480555 |
Glucose intolerance is associated with elevated serum aminotransferase independent of obesity. |
| 16386375 |
Transfection of activated Ras in human colon carcinoma cell line expressing wild-type Ras resulted in increased GGT, while reduced enzyme level was found in another cell line with constitutive Ras after transfection with dominant-negative Ras mutant. |
| 12030366 |
Gamma-glutamyl transpeptidase activity mediates NF-kappaB activation through lipid peroxidation in human leukemia U937 cells. |
| 15694941 |
After adjustment for race, sex, age, cigarette smoking, alcohol intake, and body mass index (BMI), serum concentration of GGT across all deciles was positively associated with serum concentrations of CRP. |
