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B4GALT1
| Symbol: | B4GALT1 | | Name(s): | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | B4GAL-T1, DKFZp686N19253, GGTB2, GT1, GTB, MGC50983, beta4Gal-T1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 11901181 |
deficiency causes a new congenital disorder of glycosylation (CDG), designated type IId (CDG-IId), a severe neurologic disease characterized by hydrocephalus, myopathy, and blood-clotting defects |
| 15668241 |
TNFalpha modulates the glycosylation of endothelial cells by a mechanism that directly enhances the stability of beta4GalT-1 mRNA transcripts |
| 15611127 |
E1AF has an essential role in the activation of the human GalT I gene in highly metastatic lung cancer cells |
| 17021253 |
Cycling between the trans-Golgi cisterna and the trans-Golgi network of galT is signal mediated. |
| 16786197 |
These results demonstrated that cell surface beta1,4GT1 may negatively regulate cell survival possibly through inhibiting and modulating EGFR signaling pathway. |
| 16157350 |
beta4Gal-T1 interacts preferentially with the 1,2-1,6-arm trisaccharide rather than with the 1,2-1,3-arm or 1,4-1,3-arm of a bi- or tri-antennary oligosaccharide chain of N-glycan |
| 16675551 |
Data show that expression of a hybrid enzyme of Arabidopsis thaliana xylosyltransferase and human beta-1,4-galactosyltransferase I in tobacco causes a reduction of N-glycans with potentially immunogenic core-bound xylose and fucose residues. |
Recent Publications on B4GALT1: |  |
Induction of cytokine gene expression in human thyroid epithelial cells irradiated with HZE particles (iron ions).
Gene expression profiles were examined using cDNA microarray technology in... | 24th September, 2009
| Department of Radiation Oncology, University of Pennsylvania School of
| Radiat Res. 2009 Oct;172(4):437-43.
DOI Direct Link |
Association of beta-1,3-N-acetylglucosaminyltransferase 1 and beta-1,4-galactosyltransferase 1, trans-Golgi enzymes involved in coupled poly-N-acetyllactosamine synthesis.
Poly-N-acetyllactosamine (polyLacNAc) is a linear carbohydrate polymer... | 6th August, 2009
| Department of Biochemistry, Stanford University School of Medicine,
| Glycobiology. 2009 Jun;19(6):655-64. Epub 2009 Mar 3.
DOI Direct Link |
Porcine beta1,4-galactosyltransferase-I sequence and expression.
Beta1,4-galactosyltransferase-I (B4GALT1), one of seven... | 11th June, 2009
| Department of Animal Sciences, University of Illinois at Urbana-Champaign,
| Reprod Domest Anim. 2009 Apr;44(2):228-34. Epub 2008 Jul 28.
DOI Direct Link |
Synteny conservation of the Z chromosome in 14 avian species (11 families) supports a role for Z dosage in avian sex determination.
In order to determine synteny conservation of the avian Z chromosome, a... | 13th January, 2009
| Institute of Human Genetics, University of Wurzburg, Wurzburg, Germany.
| Cytogenet Genome Res. 2008;122(2):150-6. Epub 2008 Dec 18.
DOI Direct Link |
Expression of Notch signaling pathway genes in mouse embryos lacking beta4galactosyltransferase-1.
A requirement for beta4galactosyltransferase-1 (beta4GalT-1) activity in... | 16th June, 2006
| Department of Cell Biology, Albert Einstein College of Medicine, 1300
| Gene Expr Patterns. 2006 Apr;6(4):376-82. Epub 2006 Jan 18.
DOI Direct Link |
→View more research publications. |
B4GALT1 results (if any) from reagent suppliers | 
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monoclonal antibody template
B4GalT1 encodes a type II membrane protein, which is ubiquitously expressed and ... The amino acid sequence of human B4GALT1 is 88%, 87% and ...
http://www.rndsystems.com/pdf/MAB3609.pdf...
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β-1,4-Gal-T1 (L-15) Antibody sc-17299
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, B4GALT1, 2683, 9p13.3, NM_001497 ...
http://www.scbt.com/datasheet-17299-beta-1-4-gal-t1-l-15-ant...
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2007 Addendum_No prices.indd
APLP-2 (Amyloid Precursor-like Protein 2). Mouse. Goat IgG. AF3685. 100 µg. Apolipoprotein AI. Human. Goat IgG. AF3664. 100 µg. B4GALT1. Human. Goat IgG ...
http://www.rndsystems.com/DAM_public/5946.pdf...
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β-1,4-Gal-T1 (N-20) Antibody sc-22279
Humano, B4GALT1, 2683, 9p13.3, NM_001497 · P15291 · 607091. Ratón, B4galt1, 14595, 4 A5, P15535, No Aplicable. Información sobre pedidos ...
http://www.scbt.com/es/datasheet-22279-beta-1-4-gal-t1-n-20-...
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Sept 09 NPR Non-priced version.indd
-N-acetylgalactosaminidase. C. perfringens. E. coli. 5705-GH-100. 100 µg. B4GALT1. Human. NS0. 3609-GT-010. 10 µg. (1-3)-Galactosidase. X. campestris
...
http://www.rndsystems.com/DAM_public/6445.pdf...
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β-1,4-Gal-T1 (N-20) Antibody sc-22279
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, B4GALT1, 2683, 9p13.3, NM_001497 · P15291 ...
http://www.scbt.com/de/datasheet-22279-beta-1-4-gal-t1-n-20-...
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June 07 NPR_No prices.indd
B4GALT1. Human. 394706. MAB3609. 100 µg. Bcl-10. Human/Mouse/Rat. 384202. MAB2889. 100 µg. BMP-9. Human. 360107. MAB3209. 100 µg. C1qTNF1. Human. 395526
...
http://www.rndsystems.com/DAM_public/5934.pdf...
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