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AMHR2

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Symbol:	AMHR2
Name(s):	anti-Mullerian hormone receptor, type II
Type:	protein-coding
Organism:	Homo sapiens
Synonyms:	AMHR, MISRII
Links:	Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
18230658	Observational study of gene-disease association. (HuGE Navigator)
12477536	Observational study of gene-disease association. (HuGE Navigator)
17337470	Observational study of gene-disease association. (HuGE Navigator)
17636279	Observational study of gene-disease association. (HuGE Navigator)
17988723	MISIIR is highly expressed by a wide variety of gynecologic cancers, including cancers currently without effective systemic therapies.
17636279	The observed association of the AMHR2 -482 A > G polymorphism with natural age at menopause suggests a role for AMH signaling in the usage of the primordial follicle pool in women.
12462075	Review. The role of AMHR2 in gonadal development and its mutation in the persistent Mullerian duct syndrome is discussed.
14750901	binding domains recognized by a monoclonal antibody and the natural ligand
17337470	Polymorphisms in the AMH and AMHR2 genes are associated with follicular phase E(2) levels, suggesting a role for AMH in the regulation of FSH sensitivity in the human ovary.
11588147	interacts with Mullerian inhibiting substance: an instructive developmental hormone with diagnostic and possible therapeutic applications.
→View more information from publications.

Interacting gene products
Interaction Type	Gene 1	Gene 2	Interaction description	Complex	Publication Link
HPRD	Anti mullerian hormone	anti-Mullerian hormone receptor, type II	-	-	Pubmed
HPRD	anti-Mullerian hormone	Anti mullerian hormone receptor, type 2	-	-	Pubmed

Recent Publications on AMHR2:
A role for BRCA1 in uterine leiomyosarcoma. Uterine leiomyosarcoma (ULMS) is a rare gynecologic malignancy with a low...	22nd October, 2009	Molecular Pathology Unit and Center for Cancer Research, Massachusetts	Cancer Res. 2009 Nov 1;69(21):8231-5. Epub 2009 Oct 20. DOI Direct Link
The regulatory role of Dicer in folliculogenesis in mice. Dicer is the ribonuclease III for synthesis of mature functional microRNAs...	6th October, 2009	Department of Obstetrics and Gynecology, Northwestern University, Chicago,	Mol Cell Endocrinol. 2009 Sep 30. DOI Direct Link
Constitutive WNT/Beta-Catenin Signaling in Murine Sertoli Cells Disrupts Their Differentiation and Ability to Support Spermatogenesis. Sertoli and germ cell interactions are essential for spermatogenesis and...	2nd October, 2009		Biol Reprod. 2009 Sep 30. DOI Direct Link
Dicer is required for female reproductive tract development and fertility in the mouse. Dicer encodes a riboendonuclease required for microRNA biosynthesis. Dicer...	1st October, 2009	Department of Genetics, The University of Texas M.D. Anderson Cancer	Mol Reprod Dev. 2009 Jul;76(7):678-88. DOI Direct Link
Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells. The small G-protein KRAS is crucial for mediating gonadotropin-induced...	16th September, 2009	Department of Molecular and Cellular Biology, Baylor College of Medicine,	Cancer Res. 2009 Aug 15;69(16):6463-72. DOI Direct Link
→View more research publications.

Patents:
US Patent No.	Title
7612181	Dual variable domain immunoglobulin and uses thereof
7208313	Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7291461	Methods for identifying small molecules that modulate premature translation termination and nonsense mRNA decay
7354725	Kinase peptides and antibodies
7482334	Therapeutic treatment methods
→View more patents.

AMHR2 results (if any) from reagent suppliers

AMHR2 antibody [MIG7] (ab64762) \| Abcam Mouse monoclonal [MIG7] to AMHR2. AMHR2 is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for ... http://www.abcam.com/AMHR2-antibody-MIG7-ab64762.html...
AMHR2 Antibody (N-term R80) Western blot analysis of AMHR2(arrow) using rabbit polyclonal AMHR2 Antibody (N- term R80) (Cat.#AP7111b). 293 cell lysates (2 ug/lane) either nontransfected ... http://www.abgent.com/products/catalog_no/AP7111b_AMHR2_Anti...
AMHR2 antibodies: Stem Cells > Signaling Pathways > TGF beta ... AMHR2 antibodies. ... AMHR2 antibody [MIG7]. IHC-P, WB, I-ELISA, ICC/IF. Customer Abreviews: 4 stars (out of 5). Mouse monoclonal ... http://www.abcam.com/index.html?t=244612&pt=1&c=3517&ei=&mu=...
Abgent - Phosphorylation Antibodies - Phosphorylation AP7512a, ALS2CR7 Antibody (N-term), WB, IHC, E, H, M. AP7111cNEW, AMHR2 Antibody (C-term), WB, E, H. AP7111bNEW, AMHR2 Antibody (N-term R80), WB, E, H ... http://www.abgent.com/products/category/protein_modification...
MISR II (H-150) Antibody sc-67287 Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, AMHR2, 269, 12q13.13, NM_020547 ... http://www.scbt.com/datasheet-67287-misr-ii-h-150-antibody.h...
Abgent - Stem Cell AP1474c, ALPL Antibody (Center), IHC, E, H. AP7111cNEW, AMHR2 Antibody (C-term), WB, E, H. AP7111bNEW, AMHR2 Antibody (N-term R80), WB, E, H ... http://www.abgent.com/products/category/stem_cell...
MIS-R2 Antibody #4518 The type II receptor for Mullerian inhibiting substance (MIS), also known as the anti-Mullerian hormone receptor 2 (AMHR2), binds a hormone-ligand that ... http://www.cellsignal.com/products/4518.html...

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AMHR2

Gene Information from Publications

Interacting gene products

Recent Publications on AMHR2:

Patents:

AMHR2 results (if any) from reagent suppliers