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HBP1


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Symbol:HBP1
Name(s):HMG-box transcription factor 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ16340
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16495219 EGCG blocks Wnt signaling by inducing the HBP1 transcriptional repressor and inhibits aspects of invasive breast cancer
16210625 Transgenic mice overexpressing HBP1 exhibit altered thymus cellularity and decreased thymocyte development.
15024088 Results indicate that HBP1 may contribute to the regulation of NADPH oxidase-dependent superoxide production through transcriptional repression of the p47phox gene.
16179914 in myeloid cells HBP1 may serve as a tumor suppressor and a general differentiation inducer and may synergize with chemical differentiating agents to enhance lineage-specific differentiation
15235594 HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations
14872137 NMR study of the AXH domain
16966377 these studies highlight p38 MAPK, HBP1, and RB as important components for a premature-senescence pathway with possible clinical relevance to breast cancer.
17616670 HBP1 transcriptional repressor alterations are associated with invasive breast cancer
11486012 HBP1 regulates the cell cycle in liver regeneration and provides evidence for a role in tissue maintenance.
11500377 HBP1 is a suppressor of Wnt signalling and lies in a region that is mutated in cancer.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDHistone deacetylase 1HMG-box transcription factor 1--Pubmed
HPRDRetinoblastoma 1HMG-box transcription factor 1--Pubmed
HPRDRetinoblastoma like 2HMG-box transcription factor 1--Pubmed
HPRDTranscription factor 4HMG-box transcription factor 1--Pubmed
HPRDSin3 associated polypeptide ,30KDHMG-box transcription factor 1--Pubmed
HPRDSIN3AHMG-box transcription factor 1--Pubmed

Recent Publications on HBP1:

Pubmed Logo
Knockout of p47 phox uncovers a critical role of p40 phox in reactive oxygen species production in microvascular endothelial cells.
OBJECTIVE: p40(phox) is an important regulatory subunit of NADPH oxidase,...
30th September, 2009
Faculty of Health and Medical Sciences, AY Building, University of Surrey, Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1651-6. Epub 2009 Jul 16.
DOI Direct Link
Spermine protects mice against lethal sepsis partly by attenuating surrogate inflammatory markers.
The pathogenesis of sepsis is partly attributable to dysregulated...
25th September, 2009
Department of Emergency Medicine, North Shore University Hospital, New Mol Med. 2009 Jul-Aug;15(7-8):275-82. Epub 2009 May 1.
DOI Direct Link
The effects of body temperature control on cytokine production in a rat model of ventilator-induced lung injury.
BACKGROUND AND PURPOSE: Injurious ventilation with high peak inspiratory...
22nd September, 2009
Department of Emergency and Critical Care Medicine, Chiba University Cytokine. 2009 Jul;47(1):48-55. Epub 2009 May 8.
DOI Direct Link
Bile high-mobility group box 1 contributes to gut barrier dysfunction in experimental endotoxemia.
Lipopolysaccharide (LPS) is an important factor in sepsis. LPS given by...
19th August, 2009
Dept. of Critical Care Medicine, Univ. of Pittsburgh Medical School, 1055 Am J Physiol Regul Integr Comp Physiol. 2009 Aug;297(2):R362-9. Epub 2009
DOI Direct Link
Impaired autolysosome formation correlates with Lamp-2 depletion: role of apoptosis, autophagy, and necrosis in pancreatitis.
BACKGROUND & AIMS: Acute pancreatitis constitutes a life-threatening...
17th July, 2009
Department of General, Visceral, and Transplantation Surgery, University Gastroenterology. 2009 Jul;137(1):350-60, 360.e1-5. Epub 2009 Apr 9.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for HCC

Patents:

Patents logo
US Patent No.Title
5731419 Freezing tolerance proteins Wcs19 and Wcor410 from gramineae
6092065 Method and apparatus for discovery, clustering and classification of patterns in 1-dimensional event streams
6373971 Method and apparatus for pattern discovery in protein sequences
6617312 Vasoactive amine binding molecules
6737399 Treatment of conjunctivitis

View more patents.

HBP1 results (if any) from reagent suppliers

Google CSE Logo
HBP1 Antibody / HBP1 Antibodies
HBP1 Antibody / HBP1 Antibodies. ... HBP1 specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-hbp1.html...

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Abcam antibodies and reagents product map
... GTF2IRD1 antibodies (4) · GliS2 antibodies (2) · HAP4 antibodies (1) · HBP1 antibodies (3) · HCC1 antibodies (7) · HCC1 proteins and peptides (2) ...
http://www.abcam.com/index.html?c=250...

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HBP1 siRNA (m) sc-35533
Click here for details. suitable control antibody: HBP1 (N-20): sc-8488; RT-PCR Primer also available: HBP1 (m)-PR: sc-35533-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-35533-hbp1-sirna-m.html...

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Abcam antibodies and reagents product map
... GRG (Groucho homologue) antibodies (4) · GRG (Groucho homologue) proteins and peptides (1) · HBP1 antibodies (3) · KAT3A / CBP antibodies (15) ...
http://www.abcam.com/index.html?pageconfig=productmap&cl=342...

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HBP1 Antibody / HBP1 Antibodies
HBP1 Antibody / HBP1 Antibodies. ... HBP1 特异siRNA, shRNA 质粒和shRNA 慢病毒 颗粒基因沉默子均有产品提供。 产品包括: ...
http://www.scbt.com/zh/table-hbp1.html...

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HBP1 Antibody / HBP1 Antibodies
HBP1 El siRNA, el plásmido del sHRNA y los silenciadores especificos del gene de las partículas de Lentiviral del shRNA están también disponibles. ...
http://www.scbt.com/es/table-hbp1.html...

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HBP1 (N-20) Antibody sc-8488
HBP1 (N-20) 抗体sc-8488 HBP1 (N-20) Antibody sc-8488.
http://www.scbt.com/zh/datasheet-8488-hbp1-n-20-antibody.htm...

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