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DAPP1


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Symbol:DAPP1
Name(s):dual adaptor of phosphotyrosine and 3-phosphoinositides
Type:protein-coding
Organism:Homo sapiens
Synonyms:BAM32, DKFZp667E0716
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15494510 BAM32 works downstream of Src family protein tyrosine kinases and functions to link B cell antigen receptor signals with antigen-processing pathways in B cells.
15247305 novel phosphorylation-dependent function of Bam32 in regulating Rac1 activation and actin remodeling.

Recent Publications on DAPP1:

Pubmed Logo
Genetic evidence for the role of Erk activation in a lymphoproliferative disease of mice.
Germline mutation of the linker for activation of T cells (LAT) gene at...
29th September, 2009
Laboratory of Cellular and Molecular Biology, National Cancer Institute, Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14502-7. Epub 2009 Aug 10.
DOI Direct Link
Bam32: a novel mediator of Erk activation in T cells.
Bam32 (B lymphocyte adapter molecule of 32 kDa) is an adapter protein...
18th June, 2009
Laboratory of Cellular and Molecular Biology, National Cancer Institute, Int Immunol. 2008 Jul;20(7):811-8. Epub 2008 Apr 29.
DOI Direct Link
[Identification of proteins interacting with adaptor protein Bam32]
AIM: To study the role of adaptor protein Bam32 in B cell antigen receptor...
1st May, 2009
Department of Microbiology, Third Military Medical University, Chongqing Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2005 Jul;21(4):432-4.
Regulation of B-cell entry into the cell cycle.
B cells are induced to enter the cell cycle by stimuli including ligation...
4th November, 2008
Department of Immunology and Microbiology, University of Washington, Immunol Rev. 2008 Aug;224:183-200.
DOI Direct Link
Mechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domains.
Phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) and...
14th December, 2007
Department of Chemistry, University of Illinois, Chicago, Illinois 60607, J Biol Chem. 2007 Nov 2;282(44):32093-105. Epub 2007 Sep 6.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598052 Expression profile of thyroid cancer
7384733 Interface patch clamping
7141596 Inhibitors of proteins that bind phosphorylated molecules
7067269 Assaying apparatus, kit, and method for lipids and associated enzymes
6706867 DNA array sequence selection

View more patents.

DAPP1 results (if any) from reagent suppliers

Google CSE Logo
DAPP1 antibodies: Signal Transduction > Adapters > Cytoplasmic | Abcam
DAPP1 antibodies. ... Image Abreview Publication. ab63396 · DAPP1 (phospho Y139) antibody. WB, ELISA, ICC/IF. Images. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=8803&pt=1&c=2139&ei=&mu=ra...

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BAM32 (FL-280) Antibody sc-67166
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, DAPP1, 27071, 4q23, NM_014395 ...
http://www.scbt.com/datasheet-67166-bam32-fl-280-antibody.ht...

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Technical Data Sheet Product Name: PIP Strips
Dowler, S., Currie, R.A., Downes, P.C., and Alessi, D.R. DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides Biochemical Society. ...
http://www.echelon-inc.com/objects/catalog/product/extras/14...

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BAM32 (4H9) Antibody sc-130559
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Dapp1, 26377, 3 G3, Q9QXT1 ...
http://www.scbt.com/datasheet-130559-bam32-4h9-antibody.html...

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PIP Strips Product No. P-6001
Dowler, S., Currie, R.A., Downes, P.C., and Alessi, D.R. DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides. Biochemical Society. ...
http://www.echelon-inc.com/corp/P-6001%20PIP%20Strips%20Rev%...

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BAM32 (E-10) Antibody sc-133166
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, DAPP1, 27071, 4q23, Q9UN19 ...
http://www.scbt.com/ko/datasheet-133166-bam32-e-10-antibody....

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Abcam antibodies and reagents product map
... Crk p38 antibodies (6) · CrkL antibodies (8) · CrkL proteins and peptides (1 ) · DAPP1 antibodies (3) · DARPP32 antibodies (10) · DOK1 antibodies (12) ...
http://www.abcam.com/index.html?c=2105...

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