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LAMP3


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Gene DB Home
Symbol:LAMP3
Name(s):lysosomal-associated membrane protein 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:CD208, DC-LAMP, DCLAMP, LAMP, TSC403
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17606713 DC-LAMP has a role in preventing the progression of micrometastatic melanoma in lymph nodes
16204031 Findings indicate that LAMP3 overexpression is associated with an enhanced metastatic potential and may be a prognostic factor for cervical cancer.
16887987 LAMP-1 and DC-LAMP antigen chimeras follow different trafficking pathways, induce distinct modulatory immune responses, and are able to present cryptic epitopes.
17056097 DC-LAMP staining was lost in solid type adenocarcinomas but persisted in well-differentiated areas and there was no prognostic difference in tumors that reacted with DC-LAMP.

Recent Publications on LAMP3:

Pubmed Logo
Enrichment and analysis of secretory lysosomes from lymphocyte populations.
BACKGROUND: In specialized cells, such as mast cells, macrophages, T...
22nd October, 2009
Molecular Immunology, Institute of Immunology, University Hospital BMC Immunol. 2009 Jul 29;10:41.
DOI Direct Link
Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3.
BACKGROUND AND PURPOSE: Tumour hypoxia contributes to failure of cancer...
4th September, 2009
Maastricht Radiation Oncology (MaastRO) Lab, Maastricht University, The Radiother Oncol. 2009 Sep;92(3):450-9. Epub 2009 Aug 31.
DOI Direct Link
Increased expression of CD208 (DC-LAMP) in epidermal keratinocytes of psoriatic lesions.
Psoriasis is a chronic inflammatory skin disease characterized by...
21st August, 2009
Research Center for Medical Sciences, The Jikei University School of J Dermatol. 2009 Mar;36(3):144-9.
DOI Direct Link
Molecular characterization of a new ovarian cancer cell line, YDOV-151, established from mucinous cystadenocarcinoma.
Ovarian cancer is a leading cause of death among gynecological...
14th August, 2009
Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Tohoku J Exp Med. 2009;218(2):129-39.
Annexin A8 regulates late endosome organization and function.
Different classes of endosomes exhibit a characteristic intracellular...
11th March, 2009
Institute of Medical Biochemistry, Centre for Molecular Biology of Mol Biol Cell. 2008 Dec;19(12):5267-78. Epub 2008 Oct 15.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
6008593 Closed-loop/dimming ballast controller integrated circuits
6112127 Method and system of programming at least one appliance to change state upon the occurrence of a trigger event
6248080 Intracranial monitoring and therapy delivery control device, system and method
6864643 Backlight inverter for liquid crystal display panel of asynchronous pulse width modulation driving type

View more patents.

LAMP3 results (if any) from reagent suppliers

Google CSE Logo
LAMP3 Antibody (N-term)
LAMP3 Antibody (N-term) Autophagy, LAMP3 Antibody (N-term) Cell Function, LAMP3 Antibody (N-term) Cell Membrane.
http://www.abgent.com/products/catalog_no/AP1827a...

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LAMP3 antibodies: Cancer > Tumor biomarkers > Other | Abcam
LAMP3 antibodies. ... Image Abreview Publication. ab83659 · LAMP3 antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with: ...
http://www.abcam.com/index.html?t=284981&pt=1&c=4375&ei=&mu=...

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Monoclonal Antibody to CD63 Phycoerythrin (PE) conjugated (25 tests)
The antibody MEM-259 reacts with CD63 (LAMP-3), a 40-60 kDa tetraspan glycoprotein ... LAMP-2, but not LAMP-3, are reliable markers for activation-
induced ...
http://www.exbio.cz/pdf/data_sheet_new.py/CLO000000000000057...

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Product Line - Autophagy Antibody
AP1824b, LAMP2 Antibody (C-term), WB, E, H. AP1824c, LAMP2 Antibody (Center), WB , E, H. AP1827a, LAMP3 Antibody (N-term), WB, E, H ...
http://www.abgent.com/products/category/autophagy...

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Purified Anti-human CD63 Antibody Anti-CD63 - BioLegend
Purified Anti-human CD63 Antibody Anti-CD63 - CD63 is a 53 kD type III lysosomal glycoprotein also known as LIMP, LAMP-3, gp55, and melanoma-associated ...
http://www.biolegend.com/purified-anti-human-cd63-antibody-1...

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monoclonal antibody template
28 May 2008 ... CD63, also known as LAMP-3 or ME491 (melanoma-associated antigen), is a. 30 - 60 kDa member of the tetraspanin superfamily of protein ...
http://www.rndsystems.com/pdf/MAB5048.pdf...

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human CD107b antibody, Affinity Purified conjugate
LAMP-1 and LAMP-2, but not LAMP-3, are reliable markers for activation-induced secretion of human mast cells. Cytometry A. 2004 Sep;61(1):62-8. ...
http://www.ebioscience.com/ebioscience/specs/antibody_14/14-...

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