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B3GAT1
| Symbol: | B3GAT1 | | Name(s): | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CD57, GLCATP, GlcAT-P, GlcUAT-P, HNK-1, HNK1, LEU7, NK-1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18201430 |
data suggest that the expression of CD30 and CD57 cell markers on T cells could reflect circulating effector T cell early activation in the allergic airway disease. |
| 17567734 |
A comparison of substrate specificity of beta1,3-glucuronosyltransferases revealed that GlcAT-I was selective toward Galbeta1,3Gal, whereas GlcAT-P presented a broader profile. |
| 15626024 |
first pediatric case describing coexpression of CD57 on B-lineage acute lymphoblastic leukemia |
| 12883721 |
CD57 has a role in antitumor immunity which is impaired in gastric cancer |
| 12433688 |
Expression of CD57 defines replicative senescence and HIV antigen-induced apoptotic death of CD8+ T cells, and CD57 may be involved in apoptosis and lack of proliferation. |
| 12687271 |
differences in CgA and CD57 expression in human neuroendocrine tumors are related to the degree of differentiation of the neoplasms and probably reflect the degree of maturation (functional state) of neuroendocrine granules within the neoplastic cells. |
| 15879103 |
CD8-positive T cells expressing CD57, a marker of replicative senescence, also express killer cell lectin-like receptor G1 (KLRG1); however, a population of CD57-negative KLRG1+ cells is also identified. This population may represent a "memory" phenotype. |
| 12874601 |
Polymorphic or other variation of the 11q telomere may affect the activity of B3GAT1 and be a risk factor for schizophrenia and related psychoses in the general population. |
| 14993226 |
GlcAT-P is an enzyme critical in the biosynthesis of the carbohydrate epitope HNK-1 |
| 16257185 |
It was found that collagen type IX and HNK-1 epitope were present in tears, the amount of the former being increased 2.7 times compared to normal. | →View more information from publications. |
Recent Publications on B3GAT1: |  |
Schizophrenia susceptibility genes directly implicated in the life cycles of pathogens: cytomegalovirus, influenza, herpes simplex, rubella, and Toxoplasma gondii.
Many genes implicated in schizophrenia can be related to glutamatergic... | 17th June, 2008
| 176 Downs Road, Hastings,
| Schizophr Bull. 2009 Nov;35(6):1163-82. Epub 2008 Jun 13.
DOI Direct Link |
beta-1,3-Glucuronyltransferase-1 gene implicated as a candidate for a schizophrenia-like psychosis through molecular analysis of a balanced translocation.
We have mapped and sequenced both chromosome breakpoints of a balanced... | 21st April, 2004
| Department of Neuroscience, Institute of Psychiatry, King's College
| Mol Psychiatry. 2003 Jul;8(7):654-63.
DOI Direct Link |
Cloning and chromosomal mapping of human glucuronyltransferase involved in biosynthesis of the HNK-1 carbohydrate epitope.
The HNK-1 carbohydrate is expressed on various cell adhesion molecules in... | 25th July, 2000
| Department of Biological Chemistry and CREST (Core Research for
| Genomics. 2000 Apr 15;65(2):166-73.
DOI Direct Link |
B3GAT1 results (if any) from reagent suppliers | 
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CD57 antibody, CD57 [B321 (NK-1)] (FITC) Antibody, Mouse ...
Mouse Monoclonal to CD57 HNK - 1 - FITC ; 27087; B3GAT1; 151290; Q9P2W7; CD57; GLCATP; GlcAT-P; GlcUAT-P; HNK-1; LEU7; NK-1;; ...
http://www.genwaybio.com/product_info.php?products_id=193539...
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Antibodies to Axon Guidance and Neuronal Development
purified immunoglobulin, rat ... B3gat1(117108) mouse ... B3gat1(76898) human .. . B3GAT1(27087), feline, human, mouse, rat, FACS, IHC (p), pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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Immunology Antibodies :: Page 1
B3GAT1 Monoclonal Antibody, 49-192, H, R, IHC, FACS, Beta-1,3- glucuronyltransferase 1. BANK1 Antibody, 46-963, H, E, WB, (IN) BANK1 ...
http://www.prosci-inc.com/shop/catalog1/Immunology-Antibodie...
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C0678 Monoclonal Anti-HNK-1/N-CAM (CD57) antibody produced in ...
isotype, IgM. Gene Information, human ... B3GAT1(27087). rat ... B3gat1(117108). mouse ... B3gat1(76898). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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CD57 (2Q1412) Antibody sc-70741
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, B3GAT1, 27087, 11q25, NM_018644, ...
http://www.scbt.com/datasheet-70741-cd57-2q1412-antibody.htm...
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Mouse CD & Other Cellular Antigens
CD56, NCAM, 20-185kD, IgSF, neural tissue, multiple isoforms, adhesion, neuron development, skeletal myogenesis. CD57, B3GAT1, GlucuronsyltransferaseP ...
http://www.ebioscience.com/ebioscience/whatsnew/mousecdchart...
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www.ebioscience.com
B3gat1, HNK-1. GlucuronsyltransferaseP cell adhesion molecule; memory. CD58 (H). LFA-3 not defined in mouse. CD59. Protectin, MAC- inhibitor ...
http://www.ebioscience.com/ebioscience/whatsnew/pdf/MouseCD_...
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