|
| |
DKK3
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18048388 |
Ectopic expression of Dkk3 in lung cancer cells with Dkk3 hypermethylation induced apoptosis and inhibited TCF-4 activity as well as nuclear accumulation of beta-catenin and expression of TCF-4 targets c-Myc and cyclin D1 |
| 18033687 |
Stable overexpression of murine Dkk-3 in B16F10 cells significantly increased microvessel density in a melanoma model. We postulate a novel function of Dkk-3 in endothelial cells as a differentiation factor involved in remodeling the tumor vasculature. |
| 18059033 |
High DKK3 expression in benign ganglioneuromas and down-regulation of DKK3 by MYCN in neuroblastoma might contribute to the strongly different clinical behavior of both neuroblastic tumor types. MYCN expression is inversely correlated with that of DKK3. |
| 16568085 |
loss of DKK expression plays a role in development or progression of malignant melanoma |
| 11814687 |
REIC gene expression was decreased in 14 of 24 fresh non-small cell lung cancer specimens (58%) compared to that in corresponding non-cancerous tissue. |
| 16609023 |
The methylation level of DKK3 protein was significantly higher and mRNA level wassignificantly lower in bladder tumor than in bladder mucosa. |
| 15087387 |
Transfection of Dkk-3 and dominant-negative LRP5 into osteosarcoma cells significantly reduces invasion capacity and cell motility. |
| 15516983 |
Dkk-3/REIC functions as a suppressor for human tumor growth |
| 15998302 |
Down-regulation of Dickkopf 3 in elderly schizophrenic subjects. |
| 16751809 |
Loss of Dkk-3 expression resulting in impairment of glandular structure and uncontrolled prostate epithelial cell (PrEC) proliferation, both of which are crucial for prostate cancer progression. | →View more information from publications. |
Recent Publications on DKK3: |  |
Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.
Breast cancer arises through the accumulation of multiple genetic... | 28th October, 2009
| Department of Molecular Biology, Cancer Research Institute, Sapporo
| Breast Cancer Res Treat. 2009 Oct 27.
DOI Direct Link |
Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas.
Aberrant activation of wingless (Wnt) signaling is involved in the... | 23rd October, 2009
| Department of Structural Biology, Max Planck Institute of Molecular
| Int J Cancer. 2009 Oct 21.
DOI Direct Link |
Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis.
Dysregulation of Axl and its ligand growth arrest-specific 6 is implicated... | 15th October, 2009
| Department of Molecular Oncology, Genentech Inc., South San Francisco, CA
| Oncogene. 2009 Oct 1;28(39):3442-55. Epub 2009 Jul 27.
DOI Direct Link |
Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons.
Little is known about the molecular development and heterogeneity of... | 14th October, 2009
| Department of Neurosurgery and Neurology, Massachusetts General
| J Neurosci. 2009 Sep 30;29(39):12343-54.
DOI Direct Link |
MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3.
Neuroblastoma is the most common extra-cranial solid childhood cancer; it... | 10th October, 2009
| Department of Human Genetics, Academic Medical Center, University of
| Cancer Lett. 2009 Oct 6.
DOI Direct Link |
→View more research publications. |
DKK3 results (if any) from reagent suppliers | 
|
350 aa isoform DKK3 antibody (ab2459) | Abcam
Goat polyclonal to 350 aa isoform DKK3. DKK3, like DKK1, DKK2, and DKK4, possesses an N terminal signal peptide and 2 conserved cysteine rich domains,
...
http://www.abcam.com/350-aa-isoform-DKK3-antibody-ab2459.htm...
|
 |
Dkk-3 (H-130) Antibody sc-25518
Dkk-3 shRNA (h) Lentiviral Particles, sc-41102-V, 200 µl ... See how others have used Dkk-3 (H-130): sc-25518 antibody and or Dkk-3 (H-130) antibody ...
http://www.scbt.com/datasheet-25518-dkk-3-h-130-antibody.htm...
|
 |
350 aa isoform DKK3 antibodies: Stem Cells > Signaling Pathways ...
350 aa isoform DKK3 antibodies. ... 350 aa isoform DKK3 antibody. IHC-P, ELISA. Images. Rabbit polyclonal. Reacts with: Hu. Terms and conditions · Legal ...
http://www.abcam.com/index.html?t=9030&pt=1&c=3455&ei=&mu=ra...
|
 |
Dkk-3 (N-17) Antibody sc-14956
goat polyclonal IgG, 200 µg/ml; epitope mapping near the N-terminus of Dkk-3 of human origin; recommended for detection of Dkk-3 of m, r and h origin by WB, ...
http://www.scbt.com/datasheet-14956-dkk-3-n-17-antibody.html...
|
 |
D
HPA011868, Anti-DKK3 antibody produced in rabbit, affinity isolated antibody, human ... DKK3(27122), human, IHC (p), PA, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....
|
 |
Dkk-3 siRNA (m) sc-41103
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: Dkk-3 (m)-PR: sc-41103-PR, 20 µl ...
http://www.scbt.com/ja/datasheet-41103-dkk-3-sirna-m.html...
|
 |
Abgent - Stem Cell
AP2840aNEW, DHCR24 Antibody (N-term), WB, E, M, H. AP1523b, DKK3 Antibody (C- term), IHC, E, H. AP1523a, DKK3 Antibody (N-term), WB, IHC, E, H ...
http://www.abgent.com/products/category/stem_cell...
|
 |
Search Bioportfolio and other Life Science Sites for DKK3,
or search for DKK3 on BioPortfolio's antibody search engine.
This page has been viewed 380 times
Recent Search Terms used to find this page: DKK3 IHC-P antibody | genentech and dkk3 | dkk3 antibody | human DKK3 recombinant protein | endothelial wnt dkk | DKK3 | DKK3 antibody | xenopus endothelial antibodies | xenopus endothelial antibodies | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
