Thursday November 26 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

p53


Suggest Content
Advertise Here
Gene DB Home
Symbol:p53
Name(s):p53
Type:protein-coding
Organism:Drosophila melanogaster
Synonyms:CG10873, CG31325, CG33336, Dm-P53, DmP53, dp53, prac
Links: Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18057102 These findings inform models in which signaling between p53 and cellular metabolism are integrated to regulate programmed cell death decisions.
17933869 Daxx-like protein of Drosophila interacts with Dmp53 and affects longevity and Ark mRNA level
17581633 The solution structures of their the oligomerization domain (OD) of the p53 forms of the model organisms Caenorhabditis elegans and Drosophila are presented indicating that they both differ significantly from each other as well as from human p53.
16785441 Drosophila has Chk2- and p53-independent pathways to activate caspases and induce apoptosis in response to IR.
16920621 p53 may carry out an ancestral function that promotes animal survival through the coordination of responses leading to compensatory growth after tissue damage.
16412438 Data show that p53 is necessary to maintain normal histone H3-K14 acetylation levels in Drosophila chromatin and that the role of p53 in histone modification maintenance is conserved in Drosophila and humans.
16303568 Expression of dominant-negative versions of Drosophila melanogaster p53 in adult neurons extends life span and increases genotoxic stress resistance in the fly.
16860746 The Hippo pathway is activated by Drosophila melanogaster p53 in response to Ionizing Radiation induced DNA damage.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDubiquitin-specific protease 7 CG1490-PB [Drosophila melanogaster].-USP7 interacts with ubiquitinated p53. This interaction was modelled on a demonstrated interaction between Drosophila melanogaster USP7 and p53 from an unspecified species.-Pubmed
BINDTopoisomerase I-interacting protein CG15104-PA [Drosophila melanogaster].p53 CG33336-PA, isoform A [Drosophila melanogaster].dTopors interacts with Dmp53.-Pubmed

Press Releases on p53:

BioPortfolio Logo
ASH Announces 2009 Merit Award Winners 25th November, 2009 American Society of Hematology

WASHINGTON, Nov. 25 /PRNewswire-USNewswire/ -- The American Society of Hematology (ASH) is pleased to recognize the following abstract presenters with the highest scoring abstracts in

Advocate Lance Armstrong, Scientists Edward E. Harlow, Arnold J. Levine, and Marvin Zelen to Receive American Cancer Society Highest Honor for Outstanding Contributions to Cancer Fight 19th November, 2009 American Cancer Society

Society's Medal of Honor to be Awarded on November 19

LOS ANGELES, Nov. 19 /PRNewswire-USNewswire/ -- The American Cancer Society -- the nation's leading

Quark Reports Progress of siRNA Clinical Programs; 300 Patients Dosed With Quark Pharmaceuticals' siRNA Drugs In Multiple Fully Enrolled Clinical Trials 19th November, 2009 Quark Pharmaceuticals, Inc.
    --  Pfizer Inc., which licenses PF-4523655 from Quark, has completed
        enrollment in a Phase 2 study of PF-4523655 in patients with diabetic
        macular edema (DME).  PF-4523655 is
        
Quark Pharmaceuticals to Present Data on its siRNA Therapeutic Programs in Kidney and Lung Diseases 2nd November, 2009 Quark Pharmaceuticals, Inc.

FREMONT, Calif., Nov. 2 /PRNewswire/ -- Quark Pharmaceuticals, Inc., a clinical-stage pharmaceutical company committed to discovering, developing and commercializing novel RNA interference

Champions Biotechnology, Inc. Signs Exclusive Licensing Agreement with Ramot for TAR-1, a Novel Therapeutic for the Treatment of Cancer 27th October, 2009 Champions Biotechnology, Inc.

BALTIMORE, Oct. 27 /PRNewswire-FirstCall/ -- Champions Biotechnology, Inc. (OTC Bulletin Board: CSBR), an oncology drug development

p53 results (if any) from reagent suppliers

Google CSE Logo
p53 antibody (ab2433) | Abcam
See below for p53 antibody images, references, products related to ab2433 and other tools. ... ab2433 shown recognizing mouse and human p53 in Western blot.
...
http://www.abcam.com/p53-antibody-ab2433.html...

Thumbshot
p53 Antibody #9282
Western blot analysis of extracts from HeLa cells transfected with non-targeted (-) or targeted (+) siRNA. p53 was detected using the p53 Antibody #9282, ...
http://www.cellsignal.com/products/9282.html...

Thumbshot
p53 Antibody / p53 Antibodies
p53, a DNA-binding, oligomerization domain and transcription activation domain- containing tumor suppressor, upregulates growth arrest and apoptosis-related ...
http://www.scbt.com/table-p53.html...

Thumbshot
p53 Antibody
cell cycle arrest and DNA repair or apoptosis (1). p53 is phosphorylated at multiple sites in ... enous levels of total p53 protein. The antibody does not
...
http://www.cellsignal.com/pdf/9282.pdf...

Thumbshot
Purified Anti-p53 Antibody - BioLegend
Purified Anti-p53 Antibody - p53 is a 53 kD protein that forms tetramers and functions as a tumor suppressor and transcriptional activator of genes that ...
http://www.biolegend.com/purified-anti-p53-antibody-2941.htm...

Thumbshot
Phospho-p53 (Ser33) Antibody #2526
Immunohistochemical analysis of paraffin-embedded human lung dysplasia of alveolar cells, using Phospho-p53 (Ser33) Antibody in the presence of control
...
http://www.cellsignal.com/products/2526.html...

Thumbshot
p53 (DO-1) Monoclonal Antibody sc-126
See how others have used p53 (DO-1): sc-126 antibody and or p53 (DO-1) antibody ... MSL2 Promotes Mdm2-independent Cytoplasmic Localization of p53. J. Biol. ...
http://www.scbt.com/datasheet-126-p53-do-1-antibody.html...

Thumbshot

Search Bioportfolio and other Life Science Sites for p53, or search for p53 on BioPortfolio's antibody search engine.
This page has been viewed 171 times
Recent Search Terms used to find this page:
antibody p53 | FL-393 p53 | P53 silencer | acetyl p53 antibody | p53 antibody drosophila | p53 FL-393 is not working | PAb 126 antibody p53 | p53 mapviewer | sc-126 DO1 Pab | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.