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GPI

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Symbol:	GPI
Name(s):	glucose phosphate isomerase
Type:	protein-coding
Organism:	Homo sapiens
Synonyms:	AMF, GNPI, NLK, PGI, PHI, SA-36
Links:	Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
17925402	PGI/AMF is involved in oxidative stress-induced cellular senescence and should bring novel insights into the control of cellular growth leading to a new methodology for cancer treatment.
17690101	raft-dependent endocytosis of AMF follows a distinct phosphatidylinositol 3-kinase-dependent pathway that is up-regulated in more aggressive tumor cells
12573240	crystal structure and analysis of the initial ring-opening step of catalysis
12783864	role in regulating cell proliferation
12517804	Overexpression induces neoplastic transformation and survival of NIH-3T3 fibroblasts.
15637053	phosphoglucose isomerase/autocrine motility factor activities are differentially regulated by protein kinase CK2 phosphorylation
12527360	The results demonstrate that the enzymatic activity of PGI is not essential for either receptor binding or cytokine function of human PGI.
15369782	Our results suggest that GPI variants may play a crucial role in the production of autoantibodies against ubiquitous GPI autoantigens.
15290745	In addition to the findings in rheumatoid arthritis, our results indicate that GPI is not a general target of autoantibodies in juvenile idiopathic arthritis.
15034067	T-cell dependent peripheral polyarthritis induced by recombinant human glucose-6-phosphate isomerase in genetically unaltered mice demonstrates for the first time the induction of organ-specific disease by systemic autoimmunity.
→View more information from publications.

Recent Publications on GPI:
Interaction of proteinase 3 with its associated partners: implications in the pathogenesis of Wegener's granulomatosis. PURPOSE OF REVIEW: This review focuses on proteinase 3 (PR3), the...	3rd November, 2009	aInserm U567 and Universite Paris Descartes, Hochin Hospital, Paris,	Curr Opin Rheumatol. 2009 Oct 29. DOI Direct Link
Functional aspects of CD52 in reproduction. CD52 is a GPI-anchored protein present in lymphocytes and male...	31st October, 2009	Obstetrics and Gynecology, Hyogo College of Medicine, Nishinomiya, Japan;	J Reprod Immunol. 2009 Oct 27. DOI Direct Link
Neurons in both pallidal segments change their firing properties similarly prior to closure of the eyes. Current anatomical models of the cortico-basal ganglia (BG) network...	30th October, 2009	The Hebrew University.	J Neurophysiol. 2009 Oct 28. DOI Direct Link
Gene silencing of glypican-3 in clear cell carcinoma of the ovary renders it more sensitive to the apoptotic agent paclitaxel in vitro and in vivo. Glypican-3 (GPC3) is a heparan sulfate proteoglycan that is bound to the...	29th October, 2009	Department of Obstetrics and Gynecology, Nagoya University Graduate School	Cancer Sci. 2009 Oct 1. DOI Direct Link
A novel splice variant of FR4 predominantly expressed in CD4+CD25+ regulatory T cells. Folate receptor 4 (FR4) is recently found as a lymphoid tissue specific...	29th October, 2009	Institute of Immunology, PLA, Third Military Medical University,	Immunol Invest. 2009;38(8):718-29.
→View more research publications.

Press Releases on GPI:
BioMosaics' Glypican-3 Antibody (clone 1G12) Validated at PhenoPath Laboratories for Immunohistochemical Detection of Liver Cancer	26th March, 2009	BioMosaics Inc.	BURLINGTON, Vt. and SEATTLE, March 26 /PRNewswire/ -- BioMosaics Inc., a cancer biomarker development company, announced today that its monoclonal antibody product (clone 1G12) for detection of
RAI Announces Restructuring Charges and Workforce Reduction Following Business Analysis; R.J. Reynolds Makes Modification to Portfolio Strategy	9th September, 2008	Reynolds American Inc.	WINSTON-SALEM, N.C., Sept. 9 /PRNewswire-FirstCall/ -- Reynolds American Inc. (NYSE: RAI) announced restructuring charges today related to changes planned in the organizational structures at
Biotech Tracker: Neuroimmunophilin Ligands Still Need to Demonstrate	1st July, 2001	Biotracker	Biotech Tracker:
BioSeeker launches new report "New Targets and Drug Discovery	1st January, 1970	Bioseeker
BioNews Results for GPI :
Genetics Policy Institute (GPI) and NABT to Launch Stem Cell Educational Summit in Denver	Genetic Engineering News: Nov 13 2009 2:24PM Matching: gpi
Genetics Policy Institute (GPI) and NABT to Launch Stem Cell Educational Summit in Denver	Street Insider: Nov 13 2009 1:40PM Matching: gpi
Genetics Policy Institute (GPI) and NABT to Launch Stem Cell Educational Summit in Denver	FinanzNachrichten.de: Nov 13 2009 1:24PM Matching: gpi
Genetics Policy Institute (GPI) and NABT to Launch Stem Cell Educational Summit in Denver	Globe Investor: Nov 13 2009 1:16PM Matching: gpi
Genetics Policy Institute (GPI) and NABT to Launch Stem Cell Educational Summit in Denver	Business Wire: Nov 13 2009 1:06PM Matching: gpi
Promote your company here: BioNewsCast - Press Release Distribution	→View more news.

Clinical Trials:
2 Year Study to Evaluate the Effects of GPI 1485 on [123I]b-CIT/SPECTScanning and Clinical Efficacy in Patients With PD

Patents:
US Patent No.	Title
7592431	Biodegradable T-cell Activation device
7598348	Adiponectin receptor variant, AdipoR2v2
7599933	Coupled two-way clustering analysis of data
7601332	Vitamin receptor binding drug delivery conjugates
7601351	Antibodies against protective antigen
→View more patents.

GPI results (if any) from reagent suppliers

GPI Antibody / GPI Antibodies GPI Antibody / GPI Antibodies. ... GPI specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ... http://www.scbt.com/table-gpi.html...
CD14 Monoclonal Antibody CD14 antigen is a GPI-linked glycoprotein CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including ... http://www.prosci-inc.com/shop/catalog1/CD14-Monoclonal-Anti...
GPI-PLD (38A1) Antibody sc-69780 GPI-PLD shRNA (h) Lentiviral Particles, sc-43811-V, 200 µl ... Western blot analysis of GPI-PLD purified from human plasma (A) and in human plasma (B). ... http://www.scbt.com/datasheet-69780-gpi-pld-38a1-antibody.ht...
Tracking GPI-Anchored Proteins Using a Novel Multifunctional ... terminal signal peptide and the proper GPI-anchoring sequence can be ... Technology can be used to study trafficking of GPI-anchored proteins and can be ... http://www.promega.com/scientific_posters/ps046/ps046.pdf...
GPI-PLD Antibody / GPI-PLD Antibodies GPI-PLD Antibody / GPI-PLD Antibodies. ... GPI-PLD specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ... http://www.scbt.com/table-gpi-pld.html...
Varicella Zoster Virus gpI + IV antibodies: Microbiology ... Varicella Zoster Virus gpI + IV antibodies. ... Varicella Zoster Virus gpI + IV antibody [SG1-1]. IP, WB, ELISA, ICC/IF. Mouse monoclonal ... http://www.abcam.com/index.html?t=285974&pt=1&c=3607&ei=&mu=...
GPI-PLD Antibody / GPI-PLD Antibodies GPI-PLD (15) Antibody, sc-135930, mouse IgG1, N/A, WB, IF, human. GPI-PLD specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공 ... http://www.scbt.com/ko/table-gpi-pld.html...

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GPI

Gene Information from Publications

Recent Publications on GPI:

Press Releases on GPI:

BioNews Results for GPI

Clinical Trials:

Patents:

GPI results (if any) from reagent suppliers