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GPLD1
| Symbol: | GPLD1 | | Name(s): | glycosylphosphatidylinositol specific phospholipase D1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | GPIPLD, GPIPLDM, MGC22590, PIGPLD, PIGPLD1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17949898 |
Data indicate that a critical component of Ras signaling is the activation of PLD. |
| 17467053 |
GPI-PLD probably had no contribution to hematopoietic stem cell homing, which may due to its low or no expression in cord blood, bone marrow and mobilized peripheral blood CD34(+) cells. |
| 16831865 |
Data describe the role of angiotensin II type 1A receptor phosphorylation, phospholipase D, and extracellular calcium in isoform-specific protein kinase C membrane translocation responses. |
| 14767861 |
increased serum glycosylphosphatidylinositol-specific phospholipase D is associated with insulin resistance in a cohort with a wide range of insulin sensitivity |
| 15814706 |
CTLA-4 may be stored in a specialized compartment in regulatory T cells that can be triggered rapidly for deployment to the plasma membrane in a phospholipase D- and ADP ribosylation factor-1-dependent manner |
| 12090469 |
In human ovarian cancer cell lines, GPI-PLD mRNA expression correlated with GPI-PLD enzyme activity and with the shedding of the GPI-anchored tumor and prognostic markers, urokinase receptor and CA125, from the cell surface. |
| 15500911 |
identified as component of human trypanosome lytic factor 1 (TLF1) |
| 15500962 |
PLD activation is a novel finding for the D(3) receptor, and is the first example of an effector system where D(3) signals without G(i)/G(o) protein intermediates. |
Recent Publications on GPLD1: |  |
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.
Plasma liver-enzyme tests are widely used in the clinic for the diagnosis... | 19th November, 2008
| Genetics Division, GlaxoSmithKline, King of Prussia, PA 19406, USA.
| Am J Hum Genet. 2008 Oct;83(4):520-8.
DOI Direct Link |
Transcriptome studies of bovine endometrium reveal molecular profiles characteristic for specific stages of estrous cycle and early pregnancy.
The endometrium undergoes marked functional changes during estrous cycle... | 19th November, 2008
| Laboratory for Functional Genome Analysis, Gene Center, LMU Munich,
| Exp Clin Endocrinol Diabetes. 2008 Jul;116(7):371-84. Epub 2008 Jun 17.
DOI Direct Link |
Prostasin regulates epithelial monolayer function: cell-specific Gpld1-mediated secretion and functional role for GPI anchor.
Prostasin, a trypsinlike serine peptidase, is highly expressed in... | 16th February, 2007
| Department of Medicine, University of Virginia, Charlottesville, Virginia
| Am J Physiol Cell Physiol. 2006 Dec;291(6):C1258-70. Epub 2006 Jul 5.
DOI Direct Link |
GPLD1 results (if any) from reagent suppliers | 
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GPLD1 Antibody (N-term)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GPLD1. Other
Names: ...
http://www.abgent.com/products/catalog_no/AP2405a_GPLD1_Anti...
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GPLD1 antibodies: Cardiovascular > Blood > Serum Proteins | Abcam
GPLD1 antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab76699 · GPLD1 antibody. WB, ELISA. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=205676&pt=1&c=488&ei=&mu=r...
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Abgent - Glycosylation Antibodies - Glycosylation
AT2236aNEW, GOLGA5 monoclonal antibody (M01), ELISA,RNAi-Ab,S-ELISA,WB-Ce,WB-Re, H. AP2461bNEW, GPLD1 Antibody (C-term), WB, E, H ...
http://www.abgent.com/products/category/protein_modification...
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GPI-PLD (38A1) Antibody sc-69780
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GPLD1, 2822, 6p22.2, NM_001503, ...
http://www.scbt.com/datasheet-69780-gpi-pld-38a1-antibody.ht...
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Abgent - Translation and Regulation Antibodies ...
AT2195aNEW, GGCX monoclonal antibody (M03), ELISA,IHC-P,S-ELISA,WB-Ce,WB-Re, H. AP2461bNEW, GPLD1 Antibody (C-term), WB, E, H ...
http://www.abgent.com/products/category/nuclear_signaling/tr...
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GPI-PLD Antibody / GPI-PLD Antibodies
PRODUCT NAME, CATALOG #, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. GPI-PLD (H-300 ) Antibody, sc-10788, rabbit IgG, 1-300 (h), WB, IP, IF, ELISA, m, r, h ...
http://www.scbt.com/table-gpi-pld.html...
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Abgent Antibodies and Peptides
AP8403a, GLEPP1 Antibody (Center), H. AP1076a, GNMT Antibody (N-term), H. AP6340d, GPC3 Antibody (C-term), H. AP2405a, GPLD1 Antibody (N-term), H ...
http://www.abgent.com/docs/product_investigation...
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