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GPR37
| Symbol: | GPR37 | | Name(s): | G protein-coupled receptor 37 (endothelin receptor type B-like) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | EDNRBL, PAELR, hET(B)R-LP | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 14532270 |
Glup/PACRG suppresses cell death induced by accumulation of unfolded Pael receptor and facilitates the formation of Pael-R inclusions. |
| 16539653 |
These results suggest that 4-PBA suppresses ER stress by directly reducing the amount of misfolded protein, including Pael-R accumulated in the ER. |
| 12670421 |
results show that panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity |
Recent Publications on GPR37: |  |
GPR37 surface expression enhancement via N-terminal truncation or protein-protein interactions.
GPR37, also known as the parkin-associated endothelin-like receptor... | 6th October, 2009
| Department of Pharmacology, Emory University School of Medicine, Atlanta,
| Biochemistry. 2009 Nov 3;48(43):10286-97.
DOI Direct Link |
Anatomical and histological profiling of orphan G-protein-coupled receptor expression in gastrointestinal tract of C57BL/6J mice.
G-protein-coupled receptors (GPCRs) constitute the largest family of... | 19th September, 2009
| Departments of Metabolic Disorder Research, Tsukuba Research Institute,
| Cell Tissue Res. 2009 Sep 10.
DOI Direct Link |
Macroautophagy of the GPR37 orphan receptor and Parkinson disease-associated neurodegeneration.
G-protein-coupled receptors (GPCRs) constitute the largest family of... | 17th September, 2009
| Istituto di Biologia Cellulare-Consiglio Nazionale delle Ricerche, Campus
| Autophagy. 2009 Jul;5(5):741-2. Epub 2009 Jul 9.
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[Possible involvement of HRD1 (ubiquitin E3 ligase) in neurodegenerative diseases]
G-protein-coupled receptors (GPCRs) constitute the largest family of... | 1st July, 2009
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| Nippon Yakurigaku Zasshi. 2009 May;133(5):252-6.
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Induction of macroautophagy by overexpression of the Parkinson's disease-associated GPR37 receptor.
The orphan G-protein-coupled receptor 37 (GPR37) is a substrate of parkin,... | 30th June, 2009
| Istituto di Biologia Cellulare-CNR, Campus A. Buzzati-Traverso, Via E.
| FASEB J. 2009 Jun;23(6):1978-87. Epub 2009 Feb 13.
DOI Direct Link |
→View more research publications. |
GPR37 results (if any) from reagent suppliers | 
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Pael-R (GPR37) Antibody (C-term)
Pael-R (GPR37) Antibody (C-term) Cell Function, Pael-R (GPR37) Antibody (C-term) Neurosciences, Pael-R (GPR37) Antibody (C-term) Protein Modification, ...
http://www.abgent.com/products/catalog_no/AP6410b...
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ORDERING INFORMATION
juvenile form of Parkinson's disease, GPR37 accumulates, contributing to stress- induced ... The extracellular portions of human and mouse GPR37 share 68% aa ...
http://www.rndsystems.com/pdf/MAB4450.pdf...
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Cell Line Descriptions linked to a TEV protease site and a Gal4 ...
Expression of GPR37 is controlled by the T-REx™ system. This parental cell line ... GPR37-bla U2OS cells showed significantly higher expression ...
http://www.invitrogen.com/etc/medialib/en/filelibrary/pdf/GP...
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Parkin antibody, Parkin Antibody, Rabbit Polyclonal Antibody
These substrates include SYT11, CCNE1, GPR37, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP and SEPT5. May play a more general role in the
...
http://www.genwaybio.com/product_info.php?products_id=196411...
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Pael-R (A-20) Antibody sc-27548
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GPR37, 2861, 7q31.33, NM_005302 ...
http://www.scbt.com/datasheet-27548-pael-r-a-20-antibody.htm...
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Abgent - Neurosciences Antibodies
AP6410b, Pael-R (GPR37) Antibody (C-term), WB, IHC, E, H. AP6410a, Pael-R (GPR37 ) Antibody (N-term), WB, IHC, E, H. AP6407b, Park7 (DJ-1) Antibody (C-term) ...
http://www.abgent.com/products/category/neurosciences...
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Anti-Parkin Polyclonal Antibody
Parkin may protect neurons against alpha synuclein toxicity, proteasomal dysfunction, gpr37 accumulation, and kainate-induced excitotoxicity. ...
http://www.bioreagents.com/products/productDetails/productDe...
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