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GPS2

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Symbol:	GPS2
Name(s):	G protein pathway suppressor 2
Type:	protein-coding
Organism:	Homo sapiens
Synonyms:	AMF-1, MGC104294, MGC119287, MGC119288, MGC119289
Links:	Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
17895379	Direct interactions of GPS2 with hnf4alpha and farnesoid x receptor indicate alternative coregulator recruitment strategies to cause differential transcriptional outcomes in governing bile acid biosynthesis.
16122992	the GPS2 might function in concert with hMSH4-hMSH5 during the process of homologous recombination.
11931768	Results show that the N-CoR-HDAC3 complex inhibits JNK activation through the associated GPS2 subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP-1 function.

Interacting gene products
Interaction Type	Gene 1	Gene 2	Interaction description	Complex	Publication Link
HPRD	E1A binding protein p300	G protein pathway suppressor 2	-	-	Pubmed
HPRD	G protein pathway suppressor 2	nuclear receptor co-repressor/HDAC3 complex subunit	-	-	Pubmed
HPRD	G protein pathway suppressor 2	Nuclear receptor corepressor 1	-	-	Pubmed
HPRD	G protein pathway suppressor 2	tumor protein p53	-	-	Pubmed
BIND	G protein pathway suppressor 2	tumor protein p53	p53 interacts with AMF1	-	Pubmed
HPRD	G protein pathway suppressor 2	cyclin A1 isoform a	-	-	Pubmed
BIND	G protein pathway suppressor 2	cyclin A1 isoform a	cyclin A1 interacts with GPS2.	-	Pubmed
BIND	G protein pathway suppressor 2	G protein pathway suppressor 2	AMF1 oligomerizes with itself to form a complex with an unknown number of subunits.	-	Pubmed
HPRD	G protein pathway suppressor 2	transducin beta-like 1X	-	-	Pubmed
BIND	G protein pathway suppressor 2	transducin beta-like 1X	GPS2 interacts with TBL1X (TBL1).	-	Pubmed

Recent Publications on GPS2:
A functional analysis of GABARAP on 17p13.1 by knockdown zebrafish. Array-based comparative genomic hybridization identified a 2.3-Mb...	30th January, 2010	International Research and Educational Institute for Integrated Medical	J Hum Genet. 2010 Jan 29. DOI Direct Link
G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation. We have identified G protein suppressor 2 (GPS2) as a stable component of...	9th January, 2010	Department of Biochemistry, School of Medicine, Case Western Reserve	J Biol Chem. 2009 Dec 25;284(52):36395-404. Epub 2009 Oct 26. DOI Direct Link
Constitutional haploinsufficiency of tumor suppressor genes in mentally retarded patients with microdeletions in 17p13.1. Chromosome microdeletions or duplications are detected in 10-20% of...	31st July, 2009	Department of Genetics and Evolutionary Biology, Institute of Biosciences,	Cytogenet Genome Res. 2009;125(1):1-7. Epub 2009 Jul 14. DOI Direct Link
GPS2 is required for cholesterol efflux by triggering histone demethylation, LXR recruitment, and coregulator assembly at the ABCG1 locus. Transcriptional coregulators, rather than ligand signals, are suspected to...	26th June, 2009	Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm,	Mol Cell. 2009 May 14;34(4):510-8. DOI Direct Link
G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator. RFX4_v3 (regulatory factor X4 variant 3) is a brain-specific isoform of...	21st May, 2008	Laboratories of Respiratory Biology and Neurobiology, Office of Clinical	J Biol Chem. 2008 Mar 28;283(13):8580-90. Epub 2008 Jan 24. DOI Direct Link
→View more research publications.

Patents:
US Patent No.	Title
5216507	Waveform distortion removing apparatus
6459406	GPS patch antenna attitude reference system
6603063	Plants and cells transformed with a nucleic acid from Bacillus thuringiensis strain KB59A4-6 encoding a novel SUP toxin
6607879	Compositions for the detection of blood cell and immunological response gene expression
6721561	Method for building a home-zone database using measured power strength
→View more patents.

GPS2 results from Abnova
Sponsored Results:
	GPS2 polyclonal antibody (A01) Mouse polyclonal antibody raised against a partial recombinant GPS2. Symbol: GPS2 Alias: AMF1, MGC104294, MGC119287, MGC119288, MGC119289 http://www.abnova.com/products/products_detail.asp?catalog_id=H00002874-A01
	GPS2 Recombinant Protein (P01) GPS2( AAH13652.1, 1 a.a. - 328 a.a.) full-length recombinant protein with GST tag. Symbol: GPS2 Alias: AMF-1, MGC104294, MGC119287, MGC119288, MGC119289 http://www.abnova.com/products/products_detail.asp?catalog_id=H00002874-P01
	GPS2 monoclonal antibody, clone 1E2 Mouse monoclonal antibody raised against a partial recombinant GPS2. Symbol: GPS2 Alias: AMF-1, MGC104294, MGC119287, MGC119288, MGC119289 http://www.abnova.com/products/products_detail.asp?catalog_id=MAB1096
	GPS2 Recombinant Protein (Q01) GPS2( AAH13652, 228 a.a. - 327 a.a.) partial recombinant protein with GST tag. Symbol: GPS2 Alias: AMF1 http://www.abnova.com/products/products_detail.asp?catalog_id=H00002874-Q01
	GPS2 Pre-design Chimera RNAi Homo sapiens G protein pathway suppressor 2 (GPS2), mRNA. Symbol: GPS2 Alias: AMF1 http://www.abnova.com/products/products_detail.asp?catalog_id=H00002874-R01
	GPS2 monoclonal antibody (M01), clone 3C4 Mouse monoclonal antibody raised against a partial recombinant GPS2. Symbol: GPS2 Alias: AMF1 http://www.abnova.com/products/products_detail.asp?catalog_id=H00002874-M01
→Search for GPS2 products at Abnova.

GPS2 results (if any) from reagent suppliers

GPS2 (1E2) Antibody sc-69707 GPS2 (1E2) Data. Click on image to enlarge. sc-69707. GPS2 (1E2): sc-69707. Western blot analysis of GPS2 expression in HeLa whole cell lysate. Download ... http://www.scbt.com/datasheet-69707-gps2-1e2-antibody.html...
GPS2 antibodies: Chromatin and Nuclear Signaling > Nuclear ... GPS2 antibodies. ... Image Abreview Publication. ab53406 · GPS2 antibody [clone 1E2]. WB, ELISA. Images. Mouse monoclonal ... http://www.abcam.com/index.html?t=217651&pt=1&c=3395&ei=&mu=...
Ral GPS2 (FE-63) Antibody sc-81899 Western blot analysis of Ral GPS2 expression in HeLa whole cell lysate. sc-81899 . Ral GPS2 (FE-63): sc-81899. Immunofluorescence staining of ... http://www.scbt.com/datasheet-81899-ral-gps2-fe-63-antibody....
Antibody Products - IgG Monoclonal Antibodies - GenWay Monoclonal anti-human GPS2 antibody (clone 1E2); Protein GPS2; G protein pathway suppressor 2, IgG Monoclonal ELISA, WB, Source: Mouse Reactivity: Human ... http://www.genwaybio.com/all_monoclonal_antibodies.php?fl=G&...
Ral GPS2 siRNA (h) sc-88634 Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: Ral GPS2 ... http://www.scbt.com/datasheet-88634-ral-gps2-sirna-h.html...
Protein Modification / Acetylation - Protein Modification Antibody AP1078d, GCN5 Antibody (N-term), WB, E, H. AP6892aNEW, GLUL Antibody (N-term), WB, E, H, M. AT2253a, GPS2 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H ... http://www.abgent.com/products/category/protein_modification...
Ral GPS Antibody / Ral GPS Antibodies Ral GPS2 siRNA (h): sc-88634. Ral GPS2 shRNA Plasmid (h): sc-88634-SH. Ral GPS2 shRNA (h) ... Ral GPS2 shRNA (m) Lentiviral Particles: sc-152690-V ... http://www.scbt.com/table-ral_gps.html...

Search Bioportfolio and other Life Science Sites for GPS2, or search for GPS2 on BioPortfolio's antibody search engine.
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GPS2

Gene Information from Publications

Interacting gene products

Recent Publications on GPS2:

Patents:

GPS2 results from Abnova

Sponsored Results:

GPS2 results (if any) from reagent suppliers