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GRB2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18003605 |
These results suggest that coupling of Grb2 to Gab1 mediates the hepatocyte growth factor-induced strong activation of the ERK pathway, which is required for the inhibition of HepG2 cell proliferation. |
| 17991782 |
examination of rate of association reactions between Grb2 and epidermal growth factor receptor |
| 17689925 |
These results are evidence that the Sprouty2 mechanism of ERK inhibition is independent of Grb2 binding. |
| 11897833 |
Investigation of the GRB2, GRB7, and CSH1 genes as candidates for the Silver-Russell syndrome (SRS) on chromosome 17q. |
| 15326489 |
GRB2 is necessary for RET-mediated branching of MDCK cells |
| 16038803 |
Grb2, in addition to its key function in signaling through Ras, may have a negatively regulatory role on EGF-induced PLC-gamma1 activation. |
| 15314156 |
Results suggest that MUC20 is a novel regulator of the Met signaling cascade which has a role in suppression of the Grb2-Ras pathway. |
| 12162872 |
grb2 tyrosine phosphorylation was decreased in Couzon syndrome. |
| 12006650 |
Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis |
| 11997181 |
Results indicate that leptin, after binding its receptor, leads to activation of Grb2 and several pathways for signal transduction that might lead to mitogenic effects. | →View more information from publications. |
Recent Publications on GRB2: |  |
Differential phosphorylation of the docking protein Gab1 by c-Src and the hepatocyte growth factor receptor regulates different aspects of cell functions.
The docking protein Grb2-associated binder1 (Gab1) has a central role in... | 3rd November, 2009
| Department of Life Science, National Chung Hsing University, Taichung,
| Oncogene. 2009 Nov 2.
DOI Direct Link |
Focal amplification and oncogene dependency of GAB2 in breast cancer.
DNA amplifications in breast cancer are frequent on chromosome 11q, in... | 3rd November, 2009
| Department of Pathology, Stanford University, Stanford, CA, USA.
| Oncogene. 2009 Nov 2.
DOI Direct Link |
Non-T cell activation linker regulates ERK activation in Helicobacter pylori-infected epithelial cells.
It is supposed that human pathogens, e.g. Helicobacter pylori abuse lipid... | 3rd November, 2009
| Institute of Experimental Internal Medicine, Otto von Guericke University,
| Cell Signal. 2009 Oct 28.
DOI Direct Link |
Vav and Rac activation in BCR endocytosis involves Vav recruitment to the adapter protein LAB.
The signal transduction events supporting BCR endocytosis are not well... | 28th October, 2009
| Immunobiology and Cancer Program, Oklahoma Medical Research Foundation,
| J Biol Chem. 2009 Oct 26.
DOI Direct Link |
Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGFbeta signaling.
The aim of this study was to define novel mediators of tubule injury in... | 20th October, 2009
| Department of Biochemistry and Molecular Biology, University of Louisville
| Biochim Biophys Acta. 2009 Oct 21.
DOI Direct Link |
→View more research publications. |
GRB2 results (if any) from reagent suppliers | 
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