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GRB10
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15506681 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17846126 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15506681 |
GRB10 protein products are correlated with parameters of birth size. |
| 15060076 |
Grb10 acts as a positive regulator in VEGF-R2 signaling and protects VEGF-R2 from degradation by interacting with Nedd4, a component of the endocytic machinery |
| 15870923 |
Up-regulation of growth factor receptor-bound protein 10 is associated with cervical squamous cell carcinoma |
| 17376403 |
GRB10 is a novel negative regulator of the Wnt signaling pathway. The finding that GRB10 interferes with the binding of Axin to LRP6 indicated a possible molecular mechanism by which the overexpression of GRB10 suppresses Wnt signaling. |
| 12493740 |
role in inhibiting insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor |
| 15722337 |
there is a phosphorylation-regulated complex formation of Grb10 with 14-3-3 and Akt |
| 12551896 |
The structure of this protein's SH domains affect ligand specificity. |
| 15952796 |
Ser(150) and Ser(476) of human Grb10zeta are phosphorylated in intact cells. | →View more information from publications. |
Recent Publications on GRB10: |  |
Two Short Children Born Small for Gestational Age with Insulin-Like Growth Factor 1 Receptor Haploinsufficiency Illustrate the Heterogeneity of Its Phenotype.
Context: Small for gestational age (SGA)-born children comprise a... | 30th October, 2009
| Department of Pediatrics, Subdivision of Endocrinology, Erasmus Medical
| J Clin Endocrinol Metab. 2009 Oct 28.
DOI Direct Link |
Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression.
Genomic imprinting may have evolved not only to regulate fetal growth and... | 29th October, 2009
| Clinical and Molecular Genetics Unit, Institute of Child Health,
| Hum Mol Genet. 2009 Aug 15;18(16):3066-74. Epub 2009 Jun 1.
DOI Direct Link |
Maternally-inherited Grb10 reduces placental size and efficiency.
The control of foetal growth is poorly understood and yet it is critically... | 17th October, 2009
| Department of Biology and Biochemistry, University of Bath, Building 4
| Dev Biol. 2009 Oct 13.
DOI Direct Link |
GRB10 gene and type 2 diabetes in Whites.
The control of foetal growth is poorly understood and yet it is critically... | 13th October, 2009
| Research Unit of Diabetes and Endocrine Diseases, IRCCS "Casa Sollievo
| J Intern Med. 2009 Oct 10.
DOI Direct Link |
[Occurrence of GRB10 (+11275G > A) polymorphism in Hungarian population and its relationship to glucose metabolism]
In our backstage experiment with differential display method among the... | 1st October, 2009
| Allami Nepegeszsegugyi es Tisztiorvosi Szolgalat Kozep-Dunantuli
| Orv Hetil. 2009 Oct 4;150(40):1845-51.
DOI Direct Link |
→View more research publications. |
GRB10 results (if any) from reagent suppliers | 
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GRB10 Antibody #3702
GRB10 Antibody detects endogenous levels of isoform 1 of total GRB10 protein independent of phosphorylation. The antibody does not cross-react with GRB7 or
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http://www.cellsignal.com/products/3702.html...
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GRB10 antibody (ab55153) | Abcam
Mouse monoclonal to GRB10. GRB 10 belongs to a small family of adapter proteins that interact with receptor tyrosine kinases and signaling molecules.
http://www.abcam.com/GRB10-antibody-ab55153.html...
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Phospho-GRB10 (Tyr67) Antibody #3701
Phospho-GRB10 (Tyr67) Antibody detects transfected GRB10 only when phosphorylated at tyrosine 67. The antibody does not cross-react with
phosphorylated GRB7 ...
http://www.cellsignal.com/products/3701.html...
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GRB10 antibodies: Signal Transduction > Adapters > Cytoplasmic | Abcam
GRB10 antibodies. ... GRB10 antibody. WB. Goat polyclonal. Reacts with: Hu. Predicted: Ms, Chk. ab55153 · GRB10 antibody. WB. Images. Mouse monoclonal ...
http://www.abcam.com/index.html?t=7889&pt=1&c=2139&ei=&mu=ra...
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GRB10 Antibody
endogenous levels of isoform 1 of total GRB10 protein independent of phosphorylation. ... GRB10. Antibodies are purified by protein A and peptide ...
http://www.cellsignal.com/pdf/3702.pdf...
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GRB Antibody / GRB Antibodies
GRB10 (G-3) Antibody, sc-74508, mouse IgG1, 1-130 (h), WB, IP, IF, ELISA, h > m, r ... GRB10 (K-20) Antibody, sc-1026, rabbit IgG, C-terminus (m), WB, IP, ...
http://www.scbt.com/table-grb.html...
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GRB2 Antibody #3972
3231 Phospho-Gab1 (Tyr627) Antibody · 3232 Gab1 Antibody · 3234 Phospho-Gab1 ( Tyr307) Antibody · 3701 Phospho-GRB10 (Tyr67) Antibody · 3702 GRB10 Antibody ...
http://www.cellsignal.com/products/3972.html...
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