|
| |
GRIA1
| Symbol: | GRIA1 | | Name(s): | glutamate receptor, ionotropic, AMPA 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | GLUH1, GLUR1, GLURA, HBGR1, MGC133252 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
|
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16526023 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17483093 |
the Q/R site modulates the interaction of stargazin with the transmembrane domains of AMPA receptors via an allosteric mechanism and that this modulation leads to the observed differences in the electrophysiological properties of the receptor |
| 17545169 |
biochemical study of GLUR1 L497Y AMPA receptor |
| 16526023 |
Data indicate that GRIA1 may be involved in susceptibility to DSM-IV-TR schizophrenia. |
| 17208968 |
Results indicate that CTZ and TCM target deactivation and agonist potency independently of desensitization, most likely by modifying agonist dissociation (koff). |
| 15144856 |
This study investigated whether the AMPA receptor subunit content (GluR1, GluR2, GluR2/3) within "vulnerable" vs. "resistant" sectors of the hippocampus is quantitatively altered with increasing Alzheimer Disease neuropathology |
| 15145077 |
cell loss and up-regulation of glutamate receptor subunits appear early in temporal lobe epilepsy and contribute to the synaptic plasticity that may facilitate the subsequent sprouting of mossy fiber collaterals |
| 15866042 |
According to receptor simulations, most differences can be explained if the C-terminal domain is assumed to stabilize the ligand-bound closed and open states. |
| 12125045 |
Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis. |
| 12368290 |
a short sequence present in the N-terminal domain has a role in controlling anterograde trafficking of ionotropic glutamate receptors | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Calnexin | glutamate receptor, ionotropic, AMPA 1 | - | - | Pubmed |
| HPRD | calnexin precursor | Glutamate receptor, ionotropic AMPA 1 | - | - | Pubmed |
| HPRD | Synapse associated protein 97 | glutamate receptor, ionotropic, AMPA 1 | - | - | Pubmed |
| HPRD | discs, large homolog 1 | Glutamate receptor, ionotropic AMPA 1 | - | - | Pubmed |
| HPRD | 4.1N | glutamate receptor, ionotropic, AMPA 1 | - | - | Pubmed |
| HPRD | erythrocyte membrane protein band 4.1-like 1 isoform a | Glutamate receptor, ionotropic AMPA 1 | - | - | Pubmed |
| HPRD | erythrocyte membrane protein band 4.1-like 2 | glutamate receptor, ionotropic, AMPA 1 | - | - | Pubmed |
| HPRD | Glutamate receptor, ionotropic AMPA 1 | glutamate receptor, ionotrophic | - | - | Pubmed |
| HPRD | Glutamate receptor, ionotropic AMPA 1 | homer 1 | - | - | Pubmed |
| HPRD | Glutamate receptor, ionotropic AMPA 1 | heat shock 70kDa protein 5 | - | - | Pubmed |
Recent Publications on GRIA1: |  |
Pharmacogenetics studies in STAR*D: strengths, limitations, and results.
Several lines of evidence support an important genetic contribution to the... | 3rd November, 2009
| Genetic Basis of Mood and Anxiety Disorders Unit, National Institute of
| Psychiatr Serv. 2009 Nov;60(11):1446-57.
DOI Direct Link |
Major signaling pathways in migrating neuroblasts.
Neuronal migration is a key process in the developing and adult brain.... | 12th August, 2009
| Department of Clinical Neurobiology, Interdisciplinary Center for
| Front Mol Neurosci. 2009;2:7. Epub 2009 Jul 24.
DOI Direct Link |
Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients.
Sexual dysfunction is a major contributor to treatment discontinuation and... | 4th August, 2009
| Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
| Neuropsychopharmacology. 2009 Jun;34(7):1819-28. Epub 2009 Mar 18.
DOI Direct Link |
Genome-wide association study of anthropometric traits in Korcula Island, Croatia.
AIM: To identify genetic variants underlying six anthropometric traits:... | 24th June, 2009
| Andrija Stampar School of Public Health, School of Medicine, University of
| Croat Med J. 2009 Feb;50(1):7-16.
|
Induction and expression of GluA1 (GluR-A)-independent LTP in the hippocampus.
Long-term potentiation (LTP) at hippocampal CA3-CA1 synapses is thought to... | 10th June, 2009
| Department of Physiology, Anatomy and Genetics, University of Oxford,
| Eur J Neurosci. 2009 Mar;29(6):1141-52.
DOI Direct Link |
→View more research publications. |
GRIA1 results (if any) from reagent suppliers | 
|
Antibodies to Glutamate Receptors
rat ... Gria1(50592), rat, human, ELISA (d), IHC, IP, WB, pricing. A4477, Anti- phospho-AMPA Receptor, GluR1 Subunit (pSer845) antibody produced in rabbit ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
|
 |
p-GluR-1 (Ser 849) Antibody sc-101688
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GRIA1, 2890, 5q33.2, NM_000827 ...
http://www.scbt.com/datasheet-101688-p-glur-1-ser-849-antibo...
|
 |
G5415 Anti-Glutamate Receptor AMPA R1 (GluR1) antibody produced in ...
immunoprecipitation: 1-10 μg. Gene Information, human ... GRIA1(2890). rat ... Gria1(50592). mouse ... Gria1(14799). storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
|
 |
GRIA2 antibody, GRIA2 (glutamate receptor. ionotropic. AMPA 2 ...
These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within
...
http://www.genwaybio.com/product_info.php?products_id=42968...
|
 |
GODZ antibody (ab31837) | Abcam
GODZ palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and glutamate receptors GRIA1 and GRIA2, which leads to their retention
...
http://www.abcam.com/GODZ-antibody-ab31837.html...
|
 |
Abgent - Neurosciences Antibodies
AT2261aNEW, GRIA1 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H. AT2263aNEW, GRID2 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/neurosciences...
|
 |
Ionotropic Glutamate receptor 2 antibody (ab20673) | Abcam
These channels are assembled from 4 related subunits, GLURA (GRIA1), GLURB ( GRIA2), GLURC (GRIA3), GLURD (GRIA4), with the GLURB subunit rendering the ...
http://www.abcam.com/Ionotropic-Glutamate-receptor-2-antibod...
|
 |
Search Bioportfolio and other Life Science Sites for GRIA1,
or search for GRIA1 on BioPortfolio's antibody search engine.
This page has been viewed 311 times
Recent Search Terms used to find this page: function of glutamate receptor ionotropic AMPA 1 | GRIA1 receptor | glutamate receptor 2009 | functie AMPA-1 | ampa 1 | human GRIA1 gene location | human GRIA1 gene location | GluR1 E-6 | gria1 flop variant sequence | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
