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GRIA2


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Symbol:GRIA2
Name(s):glutamate receptor, ionotropic, AMPA 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:GLUR2, GLURB, GluR-K2, HBGR2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18163426 Observational study of gene-disease association. (HuGE Navigator)
17942280 Laser capture microdissection combined with quantitative PCR was used to examine the expression of AMPA (GRIA1-4) and NMDA (GRIN1, 2A and 2B) subunit mRNA levels in Layer II/III and Layer V pyramidal cells
12859334 the Q/R site of GluRs editing is regulated in a regional manner and the GluR2 Q/R site editing is critically regulated by ADAR2 in human brain
16045445 GluR2 was localized to the perikarya and proximal dendrites of BLA neurons; dense labeling was also present over the pyramidal cell layer of hippocampal subfields CA1 and CA3
16215279 Circumstance data have indicated that the GluR2 subunits dictate Ca2+/Zn2+ permeability of AMPA receptor channels and gate injurious Ca2+/Zn2+ signals in vulnerable neurons.
15006707 R/G editing status: the relative amount of edited GLUR2 mRNA was increased in epileptic hippocampi, whereas no changes were found in neocortical tissues.
12130635 role of interaction with N-ethylmaleimide-sensitive factor in regulation of AMPA receptors by brain-derived neurotrophic factor
15144856 This study investigated whether the AMPA receptor subunit content (GluR1, GluR2, GluR2/3) within "vulnerable" vs. "resistant" sectors of the hippocampus is quantitatively altered with increasing Alzheimer Disease neuropathology
15145077 cell loss and up-regulation of glutamate receptor subunits appear early in temporal lobe epilepsy and contribute to the synaptic plasticity that may facilitate the subsequent sprouting of mossy fiber collaterals
12125045 Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis.

View more information from publications.

Recent Publications on GRIA2:

Pubmed Logo
Gene Expression Profiling for Discovery of Novel Markers of Minimal Disease.
To the Editor: As Cheung et al. (1) report, accurate assessment of minimal...
29th October, 2009
Children's Cancer Research Group, Section of Experimental Oncology, Leeds Clin Cancer Res. 2009 Oct 27.
DOI Direct Link
Recurrent copy number changes in mentally retarded children harbour genes involved in cellular localization and the glutamate receptor complex.
To determine the phenotypic significance of copy number changes (CNCs) in...
23rd July, 2009
Department of Medical Genetics, University Medical Center Utrecht, Eur J Hum Genet. 2009 Jul 22.
DOI Direct Link
A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder.
OBJECTIVE: Lithium remains a first-line treatment for bipolar disorder,...
1st July, 2009
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA. Am J Psychiatry. 2009 Jun;166(6):718-25. Epub 2009 May 15.
DOI Direct Link
Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas.
The gene expression profile of metastasizing serotonin-producing...
1st May, 2009
Division of Clinical Immunology, Rudbeck Laboratory, Uppsala University, Mod Pathol. 2009 Feb;22(2):261-72. Epub 2008 Oct 24.
DOI Direct Link
Nuclear respiratory factor 1 co-regulates AMPA glutamate receptor subunit 2 and cytochrome c oxidase: tight coupling of glutamatergic transmission and energy metabolism in neurons.
Neuronal activity, especially of the excitatory glutamatergic type, is...
3rd April, 2009
Department of Cell Biology, Neurobiology, and Anatomy, Medical College of J Neurochem. 2009 Mar;108(6):1595-606. Epub 2009 Jan 23.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7547687 Therapeutic treatment methods
7482334 Therapeutic treatment methods
7235358 Methods and compositions for diagnosing and monitoring transplant rejection

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GRIA2 results (if any) from reagent suppliers

Google CSE Logo
GRIA2 antibody, GRIA2 (glutamate receptor. ionotropic. AMPA 2 ...
Buy quality rabbit GRIA2 antibody (interacts with human), anti-GRIA2, GRIA2 ( glutamate receptor. ionotropic. AMPA 2) antibody, rabbit polyclonal antibody,
...
http://www.genwaybio.com/product_info.php?products_id=42968...

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p-GluR-2/3 (Ser 880/Ser 891) Antibody sc-101689
Mouse, Gria2, 14800, 3 E3, P23819, N/A. Mouse, Gria2, 14800, 3 E3, P23819, N/A. Mouse, Gria3, 53623, X A3.3, Q9Z2W9, N/A. Ordering Information ...
http://www.scbt.com/datasheet-101689-p-glur-2-3-ser-880-ser-...

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Ionotropic Glutamate receptor 2 antibody (ab20673) | Abcam
Additional bands: The band observed at ~50KDa is consistent with the predicted size of Gria2 protein, for which GluR2 is the precursor. ...
http://www.abcam.com/Ionotropic-Glutamate-receptor-2-antibod...

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p-GluR-2/3 (Ser 880/Ser 891) Antibody sc-17088
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, GRIA2, 2891, 4q32.1, NM_000826 ...
http://www.scbt.com/datasheet-17088-p-glur-2-3-ser-880-ser-8...

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GODZ antibody (ab31837) | Abcam
GODZ palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and glutamate receptors GRIA1 and GRIA2, which leads to their retention
...
http://www.abcam.com/GODZ-antibody-ab31837.html...

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PTPRN antibody, Receptor-type tyrosine-protein phosphatase-like N ...
GRIA2 (glutamate receptor. ionotropic. AMPA 2), IgG · D4 GDI, IgG IgY. PTPRN2 protein, IgY · Liprin-alpha-2, IgY · Rho GDP-dissociation inhibitor 2, IgY ...
http://www.genwaybio.com/product_info.php?products_id=237...

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Anti-AMPA Receptor 2 (GluR2) (extracellular)-ATTO-488
4 Nov 2007 ... (Ionotropic Glutamate receptor AMPA-selective subunit 2, GRIA2, GLUA2). Product #: AGC-005-AG. Current Lot ##: AN-01. Host: Rabbit. ...
http://www.alomone.com/system/UpLoadFiles/DGallery/Docs/AGC-...

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