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ANPEP
| Symbol: | ANPEP | | Name(s): | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | APN, CD13, LAP1, PEPN, gp150 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18085638 |
CD13 was expressed in 73% of acute myeloid leukemia patients, CD15 was expressed in 43% of patients, CD33 was expressed in 64% of patients, and CD34 was expressed in 66% of patients. |
| 11140838 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 16818694 |
The expression of APN/CD13 for patients with NSCLC to be associated with a poor prognosis and angiogenesis. This is the first study to show the relationship between the expression of APN/CD13 and the prognosis of patients with NSCLC. |
| 17897790 |
CD13 transcription is regulated by MAF via an atypical response element. |
| 15916720 |
Data identify CD13, CD107a, and CD164 as novel basophil-activation antigens. |
| 17888402 |
Finally, exogenous addition of galectin-3 into HUVECs induced angiogenesis in an APN-dependent manner. |
| 17662271 |
Expression is frequenty decreased in chronic myelogenous leukemia. |
| 17636545 |
Overexpression of ANPEP is associated with Barrett's adenocarcinomas |
| 17655775 |
There was a positive correlation between APN/CD13 expression and migratory potential in various ovarian carcinoma cell lines with accordingly enhanced secretion of endogenous MMP-2. |
| 17363739 |
CD13 functions as a novel modulator of signal transduction and cell motility via its influence on specific plasma membrane organization, thus regulating angiogenesis. | →View more information from publications. |
Recent Publications on ANPEP: |  |
Amphetamine and environmentally induced hyperthermia differentially alter the expression of genes regulating vascular tone and angiogenesis in the meninges and associated vasculature.
An amphetamine (AMPH) regimen that does not produce a prominent... | 27th October, 2009
| US Food and Drug Administration, National Center for Toxicological
| Synapse. 2009 Oct;63(10):881-94.
DOI Direct Link |
Elucidating the molecular physiopathology of acute respiratory distress syndrome in severe acute respiratory syndrome patients.
Acute respiratory distress syndrome (ARDS) is a severe form of acute lung... | 29th July, 2009
| Genome Institute of Singapore, A*STAR (Agency for Science, Technology and
| Virus Res. 2009 Nov;145(2):260-9. Epub 2009 Jul 25.
DOI Direct Link |
Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.
OBJECTIVE: Our objective was to investigate the influence of gene by... | 25th July, 2009
| Human Genetics Center, School of Public Health, University of Texas Health
| J Hypertens. 2009 Mar;27(3):491-501.
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Identification of gene signatures for invasive colorectal tumor cells.
BACKGROUND: Gene signatures of sporadic colorectal carcinoma tissues and... | 13th February, 2008
| Institut fur Allgemeine Pathologie und Pathologische Anatomie, Klinikum
| Cancer Detect Prev. 2007;31(4):282-95.
DOI Direct Link |
Aminopeptidase N reduces basolateral Na+ -K+ -ATPase in proximal tubule cells.
Aminopeptidase N/CD13 (Anpep) is a membrane-bound protein that catalyzes... | 6th December, 2007
| Department of Medicine, University of Illinois at Chicago, Chicago, IL
| Am J Physiol Renal Physiol. 2007 Oct;293(4):F1047-53. Epub 2007 Jul 18.
DOI Direct Link |
→View more research publications. |
ANPEP results (if any) from reagent suppliers | 
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Immunohistochemistry : Aminopeptidase N/ANPEP - R&D Systems
IHC Images. Immunohistochemistry : Aminopeptidase N/ANPEP. Aminopeptidase N in Human Liver Cancer. Aminopeptidase N (APN) was detected in paraffin-embedded ...
http://www.rndsystems.com/ihc_molecule_images.aspx?m=2569...
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Growth Factors/Hormones/Hormone Receptors(758) - GeneTex Inc ...
ANPEP antibody (alanyl (membrane) aminopeptidase), GTX102788, Rabbit PAb, WB, 100 μl, USD $269.00, -. ANXA2 antibody (annexin A2), GTX100046, Rabbit ...
http://www.genetex.com/WebPage/Product/Catalog.aspx?Type=Sea...
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ORDERING INFORMATION
Anti-human Aminopeptidase N/ANPEP Antibody. FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS. R&D Systems, Inc. 1-800-343-7475. 2/29/08. ORDERING INFORMATION ...
http://www.rndsystems.com/pdf/AF3815.pdf...
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Bacteria, Viruses, and Infectious Diseases(330) - GeneTex Inc ...
ANPEP antibody (alanyl (membrane) aminopeptidase), GTX102788, Rabbit PAb, WB, 100 μl, USD $269.00, -. BMPR1A antibody (bone morphogenetic protein receptor,
...
http://www.genetex.com/WebPage/Product/Catalog.aspx?Type=Sea...
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CD13 (C-17) Antibody sc-6995
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ANPEP, 290, 15q26.1, NM_001150 ...
http://www.scbt.com/datasheet-6995-cd13-c-17-antibody.html...
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C8589 Monoclonal Anti-CD13 antibody produced in mouse clone WM-47 ...
application(s), flow cytometry: 5 μL using 1 × 106 cells. isotype, IgG1. Gene Information, human ... ANPEP(290). shipped in, wet ice. storage temp. 2-8°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Abgent - Cell and Function Antibodies
AT1145aNEW, ANP32A monoclonal antibody (M01), ELISA,IF,IHC-P,WB-Ce,WB-Re, H. AP7601cNEW, ANPEP Antibody (Center), WB, E, H ...
http://www.abgent.com/products/category/cell_function...
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