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GRIN1


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Symbol:GRIN1
Name(s):glutamate receptor, ionotropic, N-methyl D-aspartate 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:NMDA1, NMDAR1, NR1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11109007 Observational study of gene-disease association. (HuGE Navigator)
11140838 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12082569 Observational study of gene-disease association. (HuGE Navigator)
12363394 Observational study of gene-disease association. (HuGE Navigator)
12679240 Observational study of gene-disease association. (HuGE Navigator)
12707933 Observational study of gene-disease association. (HuGE Navigator)
14573320 Observational study of gene-disease association. (HuGE Navigator)
15564900 Observational study of gene-disease association. (HuGE Navigator)
15635650 Observational study of gene-disease association. (HuGE Navigator)
15841096 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDactinin, alpha 2NMDA receptor 1 isoform NR1-3 precursor--Pubmed
BINDactinin, alpha 2NMDA receptor 1 isoform NR1-3 precursoralpha-actinin-2 interacts with NR1A. This interaction was modeled on a demonstrated interaction between human alpha-actinin-2 and NR1A from an unspecified species.-Pubmed
HPRDCaMK II alpha subunitNMDA receptor 1 isoform NR1-3 precursor--Pubmed
HPRDcalcium/calmodulin-dependent protein kinase IIA isoform 1Glutamate receptor ionotropic, N-methyl D-aspartate 1--Pubmed
HPRDCalnexinNMDA receptor 1 isoform NR1-3 precursor--Pubmed
HPRDCadherin 2NMDA receptor 1 isoform NR1-3 precursor--Pubmed
HPRDClathrin, heavy polypeptideNMDA receptor 1 isoform NR1-3 precursor--Pubmed
HPRDCatenin betaNMDA receptor 1 isoform NR1-3 precursor--Pubmed
HPRDChannel associated protein of synapse 110NMDA receptor 1 isoform NR1-3 precursor--Pubmed
HPRDSynapse associated protein 102NMDA receptor 1 isoform NR1-3 precursor--Pubmed

Recent Publications on GRIN1:

Pubmed Logo
GRIN1 regulates mu-opioid receptor activities by tethering the receptor and G protein in the lipid raft.
The lipid raft location of mu-opioid receptor (MOR) determines the...
29th October, 2009
University of Minnesota, United States. J Biol Chem. 2009 Oct 27.
DOI Direct Link
Behavioral deficits and subregion-specific suppression of LTP in mice expressing a population of mutant NMDA receptors throughout the hippocampus.
The NMDA receptor (NMDAR) subunit GluN1 is an obligatory component of...
2nd October, 2009
Laboratory for Molecular Pharmacology, University College London, London Learn Mem. 2009 Sep 30;16(10):635-44. Print 2009.
DOI Direct Link
Association between the G1001C polymorphism in the GRIN1 gene promoter and schizophrenia in the Iranian population.
Schizophrenia is a complex genetic disorder to which genetic variation in...
1st September, 2009
Shahid Chamran J Mol Neurosci. 2009 Jun;38(2):178-81. Epub 2008 Sep 16.
DOI Direct Link
Mutant mice with reduced NMDA-NR1 glycine affinity or lack of D-amino acid oxidase function exhibit altered anxiety-like behaviors.
Several compounds that promote activation of the N-methyl-d-aspartate...
25th April, 2009
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Pharmacol Biochem Behav. 2009 Feb;91(4):610-20. Epub 2008 Oct 7.
DOI Direct Link
Coupling of energy metabolism and synaptic transmission at the transcriptional level: role of nuclear respiratory factor 1 in regulating both cytochrome c oxidase and NMDA glutamate receptor subunit genes.
Neuronal activity and energy metabolism are tightly coupled processes....
9th April, 2009
Department of Cell Biology, Medical College of Wisconsin, Milwaukee, J Neurosci. 2009 Jan 14;29(2):483-92.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7592138 Identification of a gene expression profile that differentiates ischemic and nonischemic cardiomyopathy
5973849 Zoom lens system
6166862 Designing method of zoom optical system
6384985 Zoom lens system
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

GRIN1 results (if any) from reagent suppliers

Google CSE Logo
GRIN1 antibody, Rabbit Anti-NMDA receptor NR2A Antibody, Rabbit ...
Buy quality rabbit GRIN1 antibody (interacts with human mouse rat), anti-GRIN1, Rabbit Anti-NMDA receptor NR2A antibody, rabbit polyclonal antibody, ...
http://www.genwaybio.com/product_info.php?products_id=88024...

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GRIN1 siRNA (m) sc-145765
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: GRIN1 ...
http://www.scbt.com/datasheet-145765-grin1-sirna-m.html...

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GRIN1 antibody, NMDA, NR1, N1 Antibody, Rabbit Polyclonal Antibody
Buy quality rabbit GRIN1 antibody (interacts with target species: rat reacts with: mousebased on sequence similarity is expected to react with: human. ...
http://www.genwaybio.com/product_info.php?products_id=73746...

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Antibodies to Glutamate Receptors
mouse ... Grin1(14810) rat ... Grin1(24408), rat, mouse, IP, WB, pricing ... GRIN1(2902) mouse ... Grin1(14810), human, monkey, rodent, IHC (f), WB, pricing
...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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GRIN Antibody / GRIN Antibodies
GRIN1 shRNA Plasmid (m): sc-145765-SH. GRIN1 shRNA (m) Lentiviral Particles: sc- 145765-V. GRIN2 siRNA (h): sc-90622. GRIN2 shRNA Plasmid (h): sc-90622-SH ...
http://www.scbt.com/de/table-grin.html...

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NMDA receptor 2B antibody, NMDA receptor 2B Antibody, Rabbit ...
Subunit: Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit ... Found in a complex with GRIN1 and GRIN3B. Found in a complex with GRIN1, ...
http://www.genwaybio.com/product_info.php?products_id=196191...

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G8913 Anti-Glutamate Receptor NMDAR1 (NR1) antibody produced in ...
Gene Information, human ... GRIN1(2902). rat ... Grin1(24408). mouse ... Grin1( 14810). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=G891...

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