Gene Information from Publications |
| Publication Link |
Summary of findings |
| 11109007 |
Observational study of gene-disease association. (HuGE Navigator) |
| 11140838 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 12082569 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12363394 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12679240 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12707933 |
Observational study of gene-disease association. (HuGE Navigator) |
| 14573320 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15564900 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15635650 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15841096 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 16272960 |
Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 16476413 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16969270 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17284422 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17728671 |
Significant associations in single-marker and haplotype-based analyses pf variants and schiophrenia with depressive symptoms. |
| 12210277 |
Alteration of branch site consensus sequence and enhanced pre-mRNA splicing of an NMDAR1 intron not associated with schizophrenia. |
| 12610658 |
involvement of the GRIN1 in the pathogenesis of bipolar disorder |
| 12707933 |
Tested the association of two silent polymorphisms, a G/C substitution localized on the 5' UTR and an A/G substitution localized in exon 6, with schizophrenia and found no significant results. Haplotype analyses showed a borderline significant result. |
| 15030408 |
Absolute levels of the eight NR1 transcripts by quantitative internally standardized RT-PCR assay were measured; expression was strongly attenuated in susceptible regions of Alzheimer's disease brain |
| 15030493 |
Increased coassembly of NR1 and NR2B with PSD-95 may underlie one of the cellular mechanisms that contributes to in situ increased hyperexcitability, leading to seizure generation in focal cortical dysplasia. |
| 14573320 |
Variants in NMDAR genes are associated with alcoholism and related traits. |
| 17047094 |
NR3 nmda receptor subunits induce plasticity in NR1 with respect to subunit assembly and ligand binding/channel coupling that is unique among ligand-gated ion channel subunits. |
| 14973229 |
A significant decrease in the phosphorylation level at serine 897 (S897) of the NMDA receptor type 1 (NR1) subunit was found in brains from patients with schizophrenia |
| 14970236 |
the NR1 promoter is positively regulated by NF-kappaB site during neuronal differentiation by interacting with Sp3/Sp1 |
| 14575242 |
SIDS infants had increased mRNA in 6 nuclei of the mid-medulla, while protein was increased in the dorsal motor nucleus of the vagus (p = 0.04) and decreased in the nucleus of the spinal trigeminal tract (p = 0.03). |
| 12893641 |
human cerebral endothelial cells express the message and protein for NMDA receptors. |
| 15531111 |
A tendency to a decrease in the density of the NR1 upper band below control values is found in superior temporal cortex of bipolar and depressed patients, but not schizophrenics. |
| 17255096 |
the three amino acid tail following the TM4 region of the N-methyl-D-aspartate receptor (NR) 2 subunits is sufficient to overcome endoplasmic reticulum retention of NR1-1a subunit |
| 11803122 |
the rapidly and slowly degrading pools mainly consisted of the NR1 splice variants NR1-4a and NR1-2a. deglycosylation by endoglycosidase H indicated the presence of an immature form of NR1 that was retained in the endoplasmic reticulum. |
| 15888440 |
the conformation of NR1 subunit homodimers is affected by the partner NR2 subunits during the formation of heteromeric receptor complexes |
| 16140270 |
These results suggest that NR1 may play a role in carcinogenicity and cell death associated with one-electron reductions. |
| 15448144 |
arginine 260 is necessary for both tPA-induced cleavage of the ATD of NR1 and tPA-induced potentiation of NMDA receptor signaling |
| 12068077 |
molecular interaction between PSD-95 and nmda receptors: the effct of the NR1 splice variant on channel gating. |
| 16332682 |
ApoEr2 can form a multiprotein complex with NMDA receptor subunits and PSD95 |
| 15841096 |
the combined effects of the polymorphisms in the GRIN1 and GRIN2B genes might be involved in the etiology of schizophrenia. |
| 14732708 |
disulfide bridging and structural integrity within the NR1 N-terminal domain is requisite for cell surface N-methyl-D-aspartate receptor expression |
| 15338240 |
NMDA receptors are expressed in human epidermis under physiological conditions especially in stratum granulosum. Their reduced expression within parakeratotic epidermis in psoriasis vulgaris may be evidence of impaired intracellular calcium influx. |
| 16189506 |
Significant reductions were found in relative NMDA receptor binding in left hippocampal medication-free, but not antipsychotic-treated, schizophrenic patients. |
| 15265015 |
NMDA receptor may play a role in the regulation of keratinocyte growth and differentiation |
| 15564900 |
Genes for the NMDAR1 subunit is not frequently involved in the development of schizophrenia in the German population. |
| 16289038 |
These results demonstrate that human T lymphocytes express the NR1 subunit of NMDA receptors, which are functionally active in controlling cell activation. |
