|
| |
SLC25A4
| Symbol: | SLC25A4 | | Name(s): | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | AAC1, ANT, ANT1, PEO2, PEO3, T1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
|
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17420318 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16107323 |
The altered isoform expression in DCM hearts entails changes in the kinetic properties of total ANT protein restricting ANT function and contributing to disturbed energy metabolism in DCM. |
| 15231833 |
adenine nucleotide translocase 1-induced apoptosis requires nuclear factor B recruitment into mitochondria |
| 16020522 |
After the training period, intracellular energetic units had a higher control of mitochondrial respiration by creatine linked to a more efficient functional coupling adenine nucleotide translocase-mitochondrial creatine kinase. |
| 14729611 |
Inhibition of the PT-pore (ANT-1) via up-regulation of cyclophilin D plays a role in tumorigenesis. |
| 12565915 |
Autosomal dominant external ophthalmoplegia and bipolar affective disorder associated with a mutation in the ANT1 gene. |
| 12140186 |
A114P missense mutation in the human Ant1 protein was found to be associated with autosomal dominant progressive external ophthalmoplegia |
| 15551024 |
Increased ANT1 expression and mitochondrial dysfunction may thus be initial events in facioscapulohumeral muscular dystrophy pathogenesis |
| 15792871 |
report a novel heterozygous C to A transversion at nucleotide 269 in the ANT1 gene in a German family with Progressive External Ophthalmoplegia , predicted to convert a highly conserved alanine at codon 90 to aspartic acid. |
| 16887100 |
these data provide evidence for the involvement of ANT-1 and ANT-3 in the induction of the mitochondrial permeability transition pore and indicate the relevance of this phenomenon in ER-mitochondria Ca2+ transfer. | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Solute carrier family 25, mitochondrial carrier, member 4 | androgen receptor isoform 1 | - | - | Pubmed |
| HPRD | Solute carrier family 25, mitochondrial carrier, member 4 | ADP-ribosylation factor-like 2 | - | - | Pubmed |
| HPRD | Solute carrier family 25, mitochondrial carrier, member 4 | BCL2-associated X protein isoform beta | - | - | Pubmed |
| HPRD | Solute carrier family 25, mitochondrial carrier, member 4 | peptidylprolyl isomerase D | - | - | Pubmed |
| HPRD | solute carrier family 25 (mitochondrial carrier | BAX | - | - | Pubmed |
| HPRD | solute carrier family 25 (mitochondrial carrier | Androgen receptor | - | - | Pubmed |
| HPRD | solute carrier family 25 (mitochondrial carrier | androgen receptor isoform 1 | - | - | Pubmed |
| HPRD | solute carrier family 25 (mitochondrial carrier | nuclear receptor subfamily 3, group C, member 1 isoform alpha | - | - | Pubmed |
| HPRD | solute carrier family 25 (mitochondrial carrier | nuclear receptor subfamily 3, group C, member 1 isoform alpha | - | - | Pubmed |
Recent Publications on SLC25A4: |  |
[Expression of genes psma6 and slc25a4 in patients with acute monocytic leukemia.]
The aim of this study was to investigate the expression levels of genes... | 21st October, 2009
| Department of Clinical Hematology, The Second Hospital of Medical College,
| Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Oct;17(5):1168-73.
|
Isolation, nucleotide identification and tissue expression of three novel ovine genes-SLC25A4, SLC25A5 and SLC25A6.
The complete coding sequences of three of sheep genes SLC25A4, SLC25A5 and... | 19th September, 2009
| Faculty of Animal Science and Technology, Yunnan Agricultural University,
| Mol Biol Rep. 2009 Sep 11.
DOI Direct Link |
OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes.
Mutations in OPA1, a dynamin-related GTPase involved in mitochondrial... | 24th April, 2008
| Departement de Biochimie et Genetique, Centre Hospitalier Universitaire
| Brain. 2008 Feb;131(Pt 2):338-51. Epub 2007 Dec 24.
DOI Direct Link |
Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of mtDNA maintenance.
Mutations in nuclear genes involved in mitochondrial DNA (mtDNA)... | 24th April, 2008
| Mitochondrial Research Group, School of Neurology, Neurobiology and
| Brain. 2008 Feb;131(Pt 2):329-37. Epub 2007 Dec 7.
DOI Direct Link |
Familial parkinsonism and ophthalmoplegia from a mutation in the mitochondrial DNA helicase twinkle.
OBJECTIVE: To describe the clinical phenotype and genetic basis of a... | 1st September, 2007
| Department of Neurology, Washington University School of Medicine, PO Box
| Arch Neurol. 2007 Jul;64(7):998-1000.
DOI Direct Link |
→View more research publications. |
SLC25A4 results (if any) from reagent suppliers | 
|
ANT (N-19) Antibody sc-9299
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, SLC25A4, 291, 4q35.1, NM_001151 ...
http://www.scbt.com/datasheet-9299-ant-n-19.html...
|
 |
3C-3E
Monoclonal Anti-SLC25A4 antibody produced in mouse clone 3E1, purified immunoglobulin, buffered aqueous solution, 3E1 (monoclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
|
 |
Search Bioportfolio and other Life Science Sites for SLC25A4,
or search for SLC25A4 on BioPortfolio's antibody search engine.
This page has been viewed 186 times
Recent Search Terms used to find this page: mitochondrial dysfunction solute carrier | Slc25a4 function | opa1 plus | Describe carries family. | Describe carries family | Describe carries family | SLC25A4 regulation | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
