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GRM1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17609672 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 18059092 |
Expression of mGluR1 increases in human with hypothalamic hamartoma and in the female monkey hypothalamus at puberty. |
| 17609672 |
May contribute to melanoma susceptibility in a subgroup of patients with a low level of sun exposure and tumors located on the trunk and extremities. |
| 17430891 |
Results describe the structure of the Metabotropic glutamate receptor 1 (mGlu1)gene and demonstrated that mGlu1 transcription takes places at alternative first exons. |
| 17332361 |
Human melanoma cells release elevated levels of glutamate, implying a possible autocrine loop via GRM1. |
| 15949941 |
group I mGluRs/PLC signaling are down-regulated and desensitized in the frontal cortex in cDLB and AD cases and that these modifications worsen with progression of AD changes in the cerebral neocortex. |
| 12444084 |
identification of crucial residues for setting the activated state |
| 15155843 |
PKA activation inhibits the agonist-induced internalization and desensitization of mGluR1a and mGluR1b, probably by reducing their interaction with GRK2 and nonvisual arrestins. |
| 11951051 |
In patients with mesial temporal lobe epilepsy, mGluR1 may increase hippocampal excitability through postsynaptic activation. |
| 15383311 |
These results show that mGlu1alpha receptor interacts with caveolins and that this interaction is physiologically relevant for receptor function. | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Adenosine A1 receptor | glutamate receptor, metabotropic 1 | - | - | Pubmed |
| HPRD | adenosine A1 receptor | Metabotropic glutamate receptor 1 | - | - | Pubmed |
| HPRD | Glyceraldehyde 3 phosphate dehydrogenase | glutamate receptor, metabotropic 1 | - | - | Pubmed |
| HPRD | glyceraldehyde-3-phosphate dehydrogenase | Metabotropic glutamate receptor 1 | - | - | Pubmed |
| HPRD | Metabotropic glutamate receptor 1 | tubulin, beta 2 | - | - | Pubmed |
| HPRD | Metabotropic glutamate receptor 1 | homer 1 | - | - | Pubmed |
| HPRD | Metabotropic glutamate receptor 1 | Inositol 1,4,5-trisphosphate receptor type 1. | - | - | Pubmed |
| HPRD | glutamate receptor, metabotropic 1 | Homer 1 | - | - | Pubmed |
| HPRD | glutamate receptor, metabotropic 1 | Type 1 inositol 1,4,5 trisphosphate receptor | - | - | Pubmed |
| HPRD | glutamate receptor, metabotropic 1 | Tubulin, beta | - | - | Pubmed |
Recent Publications on GRM1: |  |
AKT2 is a downstream target of metabotropic glutamate receptor 1 (mGlu1).
Summary We reported earlier on the oncogenic properties of Grm1 by... | 22nd October, 2009
| Susan Lehman Cullman Laboratory for Cancer Research, Department of
| Pigment Cell Melanoma Res. 2009 Oct 20.
DOI Direct Link |
Variation in umami perception and in candidate genes for the umami receptor in mice and humans.
The unique taste induced by monosodium glutamate is referred to as umami... | 30th September, 2009
| Kyushu
| Am J Clin Nutr. 2009 Sep;90(3):764S-769S. Epub 2009 Jul 22.
DOI Direct Link |
A phase 0 trial of riluzole in patients with resectable stage III and IV melanoma.
PURPOSE: Ectopic expression of GRM1 in murine melanocytes results in... | 8th July, 2009
| Division of Surgical Oncology, Department of Surgery, UMDNJ-Robert Wood
| Clin Cancer Res. 2009 Jun 1;15(11):3896-902. Epub 2009 May 19.
DOI Direct Link |
Bipolar disorder in the Bulgarian Gypsies: genetic heterogeneity in a young founder population.
We report the results of follow-up analyses of 12 genomic regions showing... | 7th April, 2009
| Medical University of Sofia, Bulgaria.
| Am J Med Genet B Neuropsychiatr Genet. 2009 Mar 5;150B(2):191-201.
DOI Direct Link |
Oncogenic activities of metabotropic glutamate receptor 1 (Grm1) in melanocyte transformation.
Previously, we reported a transgenic mouse line, TG-3, that develops... | 22nd October, 2008
| Department of Chemical Biology, Ernest Mario School of Pharmacy, Susan
| Pigment Cell Melanoma Res. 2008 Jun;21(3):368-78. Epub 2008 Apr 23.
DOI Direct Link |
→View more research publications. |
GRM1 results (if any) from reagent suppliers | 
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Antibodies to Glutamate Receptors
G9665, Anti-Glutamate Receptor 1A, Metabotropic (mGluR1A) antibody produced in rabbit, affinity isolated antibody, mouse ... Grm1(14816) rat ... Grm1(24414)
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https://www.sigmaaldrich.com/etc/controller/controller-page....
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CD16 (GRM1) Antibody sc-19594
CD16 (GRM1): sc-19594. Western blot analysis of CD16 expression in human PBL whole cell lysate. 다운로드. Datasheets · Adobe Acrobat Reader 다운로드 ...
http://www.scbt.com/ko/datasheet-19594-cd16-grm1-antibody.ht...
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Anti-Human CD16 (FcγRIII) Purified
Mouse Anti-Human CD16 (Clone GRM1) recognizes Human CD16. This monoclonal antibody was purified using multi-step affinity chromatography methods such as
...
http://www.leinco.com/Monoclonal-Antibody/Anti-Human-CD16-Fc...
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CD16 (GRM1) Antibody sc-19594
CD16 (GRM1) 抗体 sc-19594 CD16 (GRM1) Antibody sc-19594.
http://www.scbt.com/ja/datasheet-19594-cd16-grm1-antibody.ht...
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G9665 Anti-Glutamate Receptor 1A, Metabotropic (mGluR1A) antibody ...
immunohistochemistry (frozen sections): 1:500. Gene Information, rat ... Grm1( 24414). mouse ... Grm1(14816). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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CD16 (GRM1) Antibody sc-19594
CD16 (GRM1) Anticuerpo sc-19594 CD16 (GRM1) Antibody sc-19594.
http://www.scbt.com/es/datasheet-19594-cd16-grm1-antibody.ht...
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Antibodies to Neurotransmitter Receptors
G9665, Anti-Glutamate Receptor 1A, Metabotropic (mGluR1A) antibody produced in rabbit, (polyclonal), affinity isolated antibody, mouse ... Grm1(14816) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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