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GRM1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17609672 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 18059092 |
Expression of mGluR1 increases in human with hypothalamic hamartoma and in the female monkey hypothalamus at puberty. |
| 17609672 |
May contribute to melanoma susceptibility in a subgroup of patients with a low level of sun exposure and tumors located on the trunk and extremities. |
| 17430891 |
Results describe the structure of the Metabotropic glutamate receptor 1 (mGlu1)gene and demonstrated that mGlu1 transcription takes places at alternative first exons. |
| 17332361 |
Human melanoma cells release elevated levels of glutamate, implying a possible autocrine loop via GRM1. |
| 15949941 |
group I mGluRs/PLC signaling are down-regulated and desensitized in the frontal cortex in cDLB and AD cases and that these modifications worsen with progression of AD changes in the cerebral neocortex. |
| 12444084 |
identification of crucial residues for setting the activated state |
| 15155843 |
PKA activation inhibits the agonist-induced internalization and desensitization of mGluR1a and mGluR1b, probably by reducing their interaction with GRK2 and nonvisual arrestins. |
| 11951051 |
In patients with mesial temporal lobe epilepsy, mGluR1 may increase hippocampal excitability through postsynaptic activation. |
| 15383311 |
These results show that mGlu1alpha receptor interacts with caveolins and that this interaction is physiologically relevant for receptor function. | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Adenosine A1 receptor | glutamate receptor, metabotropic 1 | - | - | Pubmed |
| HPRD | adenosine A1 receptor | Metabotropic glutamate receptor 1 | - | - | Pubmed |
| HPRD | Glyceraldehyde 3 phosphate dehydrogenase | glutamate receptor, metabotropic 1 | - | - | Pubmed |
| HPRD | glyceraldehyde-3-phosphate dehydrogenase | Metabotropic glutamate receptor 1 | - | - | Pubmed |
| HPRD | Metabotropic glutamate receptor 1 | tubulin, beta 2 | - | - | Pubmed |
| HPRD | Metabotropic glutamate receptor 1 | homer 1 | - | - | Pubmed |
| HPRD | Metabotropic glutamate receptor 1 | Inositol 1,4,5-trisphosphate receptor type 1. | - | - | Pubmed |
| HPRD | glutamate receptor, metabotropic 1 | Homer 1 | - | - | Pubmed |
| HPRD | glutamate receptor, metabotropic 1 | Type 1 inositol 1,4,5 trisphosphate receptor | - | - | Pubmed |
| HPRD | glutamate receptor, metabotropic 1 | Tubulin, beta | - | - | Pubmed |
Recent Publications on GRM1: |  |
The metabotropic glutamate receptor 1, GRM1: evaluation as a candidate gene for inherited forms of cerebellar ataxia.
The metabotropic glutamate (mGlu) 1 receptor, coded by the GRM1 gene, is... | 20th November, 2009
| Laboratory of Molecular Genetics, G. Gaslini Institute, Largo G. Gaslini
| J Neurol. 2009 Nov 19.
DOI Direct Link |
AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1).
We reported earlier on the oncogenic properties of Grm1 by demonstrating... | 22nd October, 2009
| Susan Lehman Cullman Laboratory for Cancer Research, Department of
| Pigment Cell Melanoma Res. 2010 Feb;23(1):103-11. Epub 2009 Oct 20.
DOI Direct Link |
Variation in umami perception and in candidate genes for the umami receptor in mice and humans.
The unique taste induced by monosodium glutamate is referred to as umami... | 30th September, 2009
| Kyushu
| Am J Clin Nutr. 2009 Sep;90(3):764S-769S. Epub 2009 Jul 22.
DOI Direct Link |
A phase 0 trial of riluzole in patients with resectable stage III and IV melanoma.
PURPOSE: Ectopic expression of GRM1 in murine melanocytes results in... | 8th July, 2009
| Division of Surgical Oncology, Department of Surgery, UMDNJ-Robert Wood
| Clin Cancer Res. 2009 Jun 1;15(11):3896-902. Epub 2009 May 19.
DOI Direct Link |
Bipolar disorder in the Bulgarian Gypsies: genetic heterogeneity in a young founder population.
We report the results of follow-up analyses of 12 genomic regions showing... | 7th April, 2009
| Medical University of Sofia, Bulgaria.
| Am J Med Genet B Neuropsychiatr Genet. 2009 Mar 5;150B(2):191-201.
DOI Direct Link |
→View more research publications. |
GRM1 results from Abnova |  | Sponsored Results: |
| GRM1 Pre-design Chimera RNAi
Homo sapiens glutamate receptor, metabotropic 1 (GRM1), mRNA. Symbol: GRM1 Alias: GPRC1A, GRM1A, MGLUR1, MGLUR1A, mGlu1
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002911-R02 |  |
| GRM1 Recombinant Protein (Q01)
GRM1( NP_000829, 387 a.a. - 486 a.a.) partial recombinant protein with GST tag. Symbol: GRM1 Alias: GPRC1A, GRM1A, MGLUR1, MGLUR1A, mGlu1
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002911-Q01 | |
| GRM1 polyclonal antibody (A01)
Mouse polyclonal antibody raised against a partial recombinant GRM1. Symbol: GRM1 Alias: GPRC1A, GRM1A, MGLUR1, MGLUR1A, mGlu1
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002911-A01 | |
| GRM1 monoclonal antibody (M02), clone 1F7
Mouse monoclonal antibody raised against a partial recombinant GRM1. Symbol: GRM1 Alias: GPRC1A, GRM1A, MGLUR1, MGLUR1A, mGlu1
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002911-M02 | |
| GRM1 polyclonal antibody
Rabbit polyclonal antibody raised against synthetic peptides of GRM1. Symbol: GRM1 Alias: GPRC1A, GRM1A, MGLUR1, MGLUR1A, mGlu1
http://www.abnova.com/products/products_detail.asp?catalog_id=PAB1119 | |
| GRM1 polyclonal antibody
Rabbit polyclonal antibody raised against synthetic peptides of GRM1. Symbol: GRM1 Alias: GPRC1A, GRM1A, MGLUR1, MGLUR1A, mGlu1
http://www.abnova.com/products/products_detail.asp?catalog_id=PAB11697 | |
→Search for GRM1 products at Abnova. |
GRM1 results (if any) from reagent suppliers | 
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CD16 (GRM1) Antibody sc-19594
CD16 (GRM1): sc-19594. Western blot analysis of CD16 expression in human PBL whole cell lysate. Download. Datasheets · Get Adobe Acrobat Reader ...
http://www.scbt.com/datasheet-19594-cd16-grm1-antibody.html...
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CD16 antibody [GRM1] (Biotin) (ab82442) | Abcam
Mouse monoclonal [GRM1] to CD16 (Biotin). CD16 (FcgammaRIII) serves as a low affinity IgG receptor. Human CD16 is expressed in two forms CD16a and CD16b.
http://www.abcam.com/CD16-antibody-GRM1-Biotin-ab82442.html...
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GRM1 antibody, Metabotropic glutamate receptor 1 Antibody, Rabbit ...
Buy quality rabbit GRM1 antibody (interacts with human), anti-GRM1, Metabotropic glutamate receptor 1 antibody, rabbit polyclonal antibody, ...
http://www.genwaybio.com/product_info.php?products_id=10631...
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Antibodies to Glutamate Receptors
G9665, Anti-Glutamate Receptor 1A, Metabotropic (mGluR1A) antibody produced in rabbit, polyclonal, affinity isolated antibody, mouse ... Grm1(14816) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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Homer 1A, 1B + 1C antibody, Homer 1A+1B+1C Antibody, Rat ...
By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, ... May also couple GRM1 to PI3 kinase through its interaction with CENTG1. ...
http://www.genwaybio.com/product_info.php?products_id=195359...
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CD16 Antibody / CD16 Antibodies
CD16 (GO22) Antibody, sc-19589, mouse IgM, FL (h), IF, IHC(P), FCM, human. CD16 (GRM1) Antibody, sc-19594, mouse IgG2a, FL (h), WB, IP, IF, FCM, human ...
http://www.scbt.com/table-cd16.html...
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G9665 Anti-Glutamate Receptor 1A, Metabotropic (mGluR1A) antibody ...
immunohistochemistry (frozen sections): 1:500. Gene Information, rat ... Grm1( 24414). mouse ... Grm1(14816). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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