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GRM7


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Symbol:GRM7
Name(s):glutamate receptor, metabotropic 7
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ40498, GLUR7, GPRC1G, MGLUR7, mGlu7
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18329248 Observational study of gene-disease association. (HuGE Navigator)
11912074 Observational study of gene-disease association. (HuGE Navigator)
17167337 Polymorphism not associated with panic disorder.
12052533 Identified additional splicing variants involving the 3' end of the GRM7 coding sequence and resulting in three putative novel isoforms.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDcalmodulin 1glutamate receptor, metabotropic 7 isoform b precursor--Pubmed
HPRDcalmodulin 1glutamate receptor, metabotropic 7 isoform b precursor--Pubmed
HPRDcalmodulin 2glutamate receptor, metabotropic 7 isoform b precursor--Pubmed
HPRDcalmodulin 2glutamate receptor, metabotropic 7 isoform b precursor--Pubmed
HPRDcalmodulin 3glutamate receptor, metabotropic 7 isoform b precursor--Pubmed
HPRDcalmodulin 3glutamate receptor, metabotropic 7 isoform b precursor--Pubmed
HPRDGuanine nucleotide binding protein G(q) alpha subunitglutamate receptor, metabotropic 7 isoform b precursor--Pubmed
HPRDguanine nucleotide binding protein, q polypeptideMetabotropic glutamate receptor 7--Pubmed
HPRDMetabotropic glutamate receptor 7tubulin, alpha 4a--Pubmed
HPRDMetabotropic glutamate receptor 7tubulin, alpha 3c--Pubmed

Recent Publications on GRM7:

Pubmed Logo
A family-based association study of DNA sequence variants in GRM7 with schizophrenia in an Indonesian population.
We previously reported genome-wide significant linkage to chromosome 3p in...
30th July, 2009
Western Australian Institute for Medical Research, Centre for Medical Int J Neuropsychopharmacol. 2009 Oct;12(9):1283-9. Epub 2009 Jul 29.
DOI Direct Link
Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers.
MicroRNAs (miRNAs) regulate messenger RNA (mRNA) translation in a...
18th June, 2009
Laboratory of Molecular Pathophysiology, National Institute of Mental Neuropsychopharmacology. 2009 May;34(6):1395-405. Epub 2008 Aug 13.
DOI Direct Link
Association study of polymorphisms in the group III metabotropic glutamate receptor genes, GRM4 and GRM7, with schizophrenia.
Based on the hypothesis that a glutamatergic dysfunction is involved in...
11th June, 2009
Division of Human Molecular Genetics, Research Center for Genetic Psychiatry Res. 2009 May 15;167(1-2):88-96. Epub 2009 Apr 7.
DOI Direct Link
GRM7 variants confer susceptibility to age-related hearing impairment.
Age-related hearing impairment (ARHI), or presbycusis, is the most...
28th February, 2009
House Ear Institute, Gonda Research Center for Cell and Molecular Biology, Hum Mol Genet. 2009 Feb 15;18(4):785-96. Epub 2008 Dec 1.
DOI Direct Link
Genome-wide association study of response to methylphenidate in 187 children with attention-deficit/hyperactivity disorder.
We conducted a genome-wide association study of symptom response in an...
7th January, 2009
Department of Psychiatry, Massachusetts General Hospital and Harvard Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5;147B(8):1412-8.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608406 Diagnostic markers of stroke and cerebral injury and methods of use thereof
7341838 Polypeptides related to natriuretic peptides and methods of their identification and use
6727063 Single nucleotide polymorphisms in genes
5781521 Optical disk recording/reproducing apparatus

GRM7 results (if any) from reagent suppliers

Google CSE Logo
Antibodies to Glutamate Receptors
GRM7(2917), human, IHC (p), pricing. G2045, Anti-Glutamate Receptor 8, Metabotropic antibody produced in rabbit, (polyclonal), affinity isolated
antibody ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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mGluR-7 (N-19) Antibody sc-47156
Human, GRM7, 2917, 3p26.1, NM_000844, NM_181874, NM_181875 · Q14831 · 604101. Mouse, Grm7, 108073, 6 E3, Q68ED2, N/A. Ordering Information ...
http://www.scbt.com/datasheet-47156-mglur-7-n-19-antibody.ht...

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Anti-mGluR 2/3 Polyclonal Antibody
... GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. ...
http://www.bioreagents.com/products/productDetails/productDe...

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mGluR-7 (H-47) Antibody sc-99045
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, GRM7, 2917, 3p26.1, Q14831 ...
http://www.scbt.com/datasheet-99045-mglur-7-h-47-antibody.ht...

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Abgent - Neurosciences Antibodies
AT2264aNEW, GRM2 monoclonal antibody (M03), ELISA,S-ELISA, H. AT2265aNEW, GRM7 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/neurosciences...

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mGluR Antibody / mGluR Antibodies
PRODUCT NAME, CATALOG #, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. mGluR-1a/b (G- 13) Antibody, sc-47130, goat IgG, extracellular (h), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/table-mglur.html...

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mGluR-7 siRNA (m) sc-61039
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Mouse, Grm7, 108073, 6 E3, Q68ED2 ...
http://www.scbt.com/datasheet-61039-mglur-7-sirna-m.html...

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