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CXCL1
| Symbol: | CXCL1 | | Name(s): | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | FSP, GRO1, GROa, MGSA, MGSA alpha, MGSA-a, NAP-3, SCYB1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18211687 |
In addition to transcriptional up regulation of CXCL1, these primary cells exhibited the greatest IL-8 secretion and cell damage in response to stimulation with an acapsular strain of C. neoformans. |
| 18283335 |
CXCL1 secreted by endothelial cells induces tumor cell invasion |
| 15843053 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18056965 |
GRO-alpha may be a novel diagnostic marker for age-related pathology, including cancer. |
| 17703315 |
During treatment of ulceretive colitis with corticosteroids CXCL1/CXCL9 were decreased. |
| 17581194 |
PAR-2 plays a role in serine protease-mediated regulation of IL-8 and GRO-alpha in nasal epithelial cells and may be involved in the pathophysiology of rhinosinusitis. |
| 17456471 |
CX3CR1 and CX3CL1 mediate heterotypic anchorage of foam cells to coronary artery smooth muscle cells in the context of atherosclerosis |
| 15492419 |
This suggests that GRO-alpha plays a role in the infiltration of neutrophils into the lesional skin and in bulla formation in linear IgA bullous dermatosis. |
| 15994316 |
KC (CXCL1) mRNA is regulated by functionally independent AU-rich sequence motifs |
| 16086366 |
We propose that the concurrence of CXCR2 on oligodendrocytes and induced CXCL1 on hypertrophic astrocytes in MS provides a novel mechanism for recruitment of oligodendrocytes to areas of damage, an essential prerequisite for lesion repair. | →View more information from publications. |
Recent Publications on CXCL1: |  |
Airway exposure to silica coated TiO2 nanoparticles induces pulmonary neutrophilia in mice.
The importance of nanotechnologies and engineered nanoparticles has grown... | 31st October, 2009
| Unit of Excellence for Immunotoxicology, Finnish Institute of Occupational
| Toxicol Sci. 2009 Oct 29.
DOI Direct Link |
CXCR2 Is Required for Neutrophilic Airway Inflammation and Hyperresponsiveness in a Mouse Model of Human Rhinovirus Infection.
Human rhinovirus (RV) infection is responsible for the majority of... | 30th October, 2009
| *Department of Molecular and Integrative Physiology.
| J Immunol. 2009 Oct 28.
DOI Direct Link |
Lipopolysacchride-treated mammary carcinomas secrete proinflammatory chemokines and exhibit reduced growth rates in vivo, but not in vitro.
Toll-like receptors (TLR) are pattern recognition receptors that play a... | 29th October, 2009
| Department of Biology, Lafayette College, Easton, PA 18042, USA.
| Immunol Invest. 2009;38(8):730-48.
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Eosinophils infiltrate thyroids, but have no apparent role in induction or resolution of experimental autoimmune thyroiditis in interferon-gamma mice.
Summary Granulomatous experimental autoimmune thyroiditis (G-EAT) is... | 23rd October, 2009
| Department of Internal Medicine, University of Missouri School of
| Immunology. 2009 Oct 21.
DOI Direct Link |
TSLP Induces Chemotactic and Pro-survival Effects in Eosinophils: Implications in Allergic Inflammation.
Thymic stromal lymphopoietin (TSLP) is highly expressed by bronchial... | 22nd October, 2009
| Department of Chemical Pathology, The Chinese University of Hong Kong,
| Am J Respir Cell Mol Biol. 2009 Oct 20.
DOI Direct Link |
→View more research publications. |
CXCL1 results (if any) from reagent suppliers | 
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CXCL1 Antibody Anti-CXCL1
CXCL1 antibody can be used for Western blot at a suggested dilution at 0.0758痢/ ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should ...
http://www.prosci-inc.com/shop/catalog1/CXCL1-Antibody-p-101...
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Human CXCL1/2/3/GRO Pan Specific MAb (Clone 31716)
Neutralization of Human CXCL1/2/3 Bioactivity - The exact concentration of antibody required to neutralize human CXCL1/2/3 activity is dependent on the ...
http://www.rndsystems.com/pdf/MAB276.pdf...
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FlowCytomix Mouse CXCL1/KC Simplex Kit BMS86019FF
detection of mouse CXCL1/KC by Flow Cytometry. BMS86019FF is for research use only. ... Chemokine KC (CXCL1) has been considered to be a murine ...
http://www.bendermedsystems.com/bm_products/MAN/86019FF.pdf...
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Human CXCL1/2/3/GRO Pan Specific MAb (Clone 29702)
Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are ... This antibody recognizes human CXCL1, human CXCL2 and human CXCL3
...
http://www.rndsystems.com/pdf/MAB2761.pdf...
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PE/Cy5 Anti-human CD182 CXCR2 Antibody Anti-CD182 - BioLegend
(CXCL1, CXCL2, CXCL3). Antigen References: 1. Chuntharapai, A., et al., 1994. J. Immunol. 153: 5682. 2. Wilson, S., et al., 2005. J. Biol. Chem. 280: 28663. ...
http://www.biolegend.com/pe-cy5-anti-human-cd182-cxcr2-antib...
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Quantikine Mouse CXCL1/KC ELISA
Mouse KC, also known as CXCL1 or N51, was originally identified in fibroblasts as a. PDGF-induced immediate early gene that encodes a secretory protein of ...
http://www.rndsystems.com/pdf/mkc00b.pdf...
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PE/Cy5 Anti-human CD181 CXCR1 Antibody Anti-CD181 - BioLegend
Ligand Receptor: IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), GRO-a(CXCL1). Antigen References: 1. Chuntharapai, A., et al., 1994. J. Immunol. 153: 5682. ...
http://www.biolegend.com/pe-cy5-anti-human-cd181-cxcr1-antib...
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