Recent Publications on : |  |
Expression QTL and regulatory network analysis of microtubule-associated protein tau gene.
Numerous studies have shown that the microtubule-associated protein tau...
Direct Link | 13th October, 2009
| Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong
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Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.
Wnt-signal transduction is critical for development and tissue homeostasis...
Direct Link | 6th October, 2009
| [1] Division of Molecular Genetics, Netherlands Cancer Institute,
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Validating GSK3 as an in vivo target of lithium action.
Lithium is widely used to treat bipolar disorder, but its mechanism of...
Direct Link | 17th September, 2009
| Department of Medicine, University of Pennsylvania School of Medicine,
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Knockout mice in understanding the mechanism of action of lithium.
Lithium inhibits IMPase (inositol monophosphatase) activity, as well as...
Direct Link | 17th September, 2009
| Faculty of Health Sciences, Ben Gurion University of the Negev,
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Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment.
Chondrosarcomas are notorious for their resistance to conventional...
Direct Link | 12th September, 2009
| Department of Pathology and Orthopedic Surgery, Leiden University Medical
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Glycogen synthase kinase 3B in bovine oocytes and granulosa cells: possible involvement in meiosis during in vitro maturation.
Glycogen synthase kinase 3 (GSK3) regulates cellular metabolism and cell...
Direct Link | 11th September, 2009
| Physiologie de la Reproduction et des Comportements, UMR6175 INRA, CNRS,
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Layered functional network analysis of gene expression in human heart failure.
BACKGROUND: Although dilated cardiomyopathy (DCM) is a leading cause of...
Direct Link | 25th July, 2009
| Institute of Clinical Pharmacology, The Second Affiliated Hospital of
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Review of Lithium Effects on Brain and Blood.
Clinicians have long used Lithium to treat manic depression. They have...
Direct Link | 16th June, 2009
| W. M. Keck Center for Collaborative Neuroscience Rutgers, State University
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Estrogen rapidly activates the PI3K/AKT pathway and hypoxia-inducible factor 1 and induces vascular endothelial growth factor A expression in luminal epithelial cells of the rat uterus.
We have previously shown that 17beta-estradiol (E(2)) increases vascular...
Direct Link | 8th May, 2009
| Department of Physiology, University of Maryland School of Medicine,
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Lithium reduces Gsk3b mRNA levels: implications for Alzheimer Disease.
BACKGROUND: There is evidence of increased systemic expression of active...
Direct Link | 2nd May, 2009
| Laboratory of Neurosciences-LIM27, Department & Institute of Psychiatry,
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Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms.
Given the mounting convergent evidence implicating many more genes in...
Direct Link | 7th April, 2009
| Department of Psychiatry, Indiana University School of Medicine,
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Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation.
Based on extensive preclinical data, glycogen synthase kinase-3 (GSK-3)...
Direct Link | 13th January, 2009
| Center for Translational Medicine, Thomas Jefferson University,
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Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease.
OBJECTIVE: We examined the epistatic effect between haplotypes of glycogen...
Direct Link | 25th December, 2008
| Prince of Wales Medical Research Institute, Randwick, Sydney, Australia.
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Association of GSK3B with Alzheimer disease and frontotemporal dementia.
BACKGROUND: Deposits of abnormally hyperphosphorylated tau are a hallmark...
Direct Link | 19th November, 2008
| Department of Neurology, David Geffen School of Medicine, University of
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GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism.
Glycogen synthase kinase-3 (GSK-3) is a widely expressed and highly...
Direct Link | 19th November, 2008
| Division of Oral Biology and Department of Physiology and Pharmacology,
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