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ANXA1


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Gene DB Home
Symbol:ANXA1
Name(s):annexin A1
Type:protein-coding
Organism:Homo sapiens
Synonyms:ANX1, LPC1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11574426 Observational study of gene-disease association. (HuGE Navigator)
15476183 Observational study of gene-disease association. (HuGE Navigator)
17873281 the confluence-dependent interaction of cPLA(2)alpha and annexin A1 at the Golgi acts as a novel molecular switch controlling cPLA(2)alpha activity and endothelial cell prostaglandin generation.
17932043 Ca(2+)-dependent binding of S100A11 to ANXA1 facilitated the binding of the latter to cPLA(2), resulting in inhibition of cPLA(2) activity
17994624 Human clinical specimens showed that ANNA1 expression was reduced in bladder transitional cell carcinomas(TCC) compared to normal urothelium.
16899607 The high ANXA1 expression is frequent in esophageal and esophagogastric junction adenocarcinomas, correlates with more advanced pathologic T stage and the presence of distant metastasis, and is an independent prognostic factor for patient survival.
17681950 proteinase 3 has a critical role in annexin 1 cleavage in activated neutrophils
15064349 annexin II serves as both ligand and receptor in promoting phagocytosis.
16014420 These results suggest that annexin A1 may be a key protein involved in CF pathogenesis especially in relation to the not well defined field of inflammation in CF.
16675446 AnxA1 has a role in stimulating SKCO-15 cell migration through nFPR activation

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDAnnexin Iformyl peptide receptor 1--Pubmed
HPRDAnnexin Ikeratin 8--Pubmed
HPRDannexin IKeratin 8--Pubmed
HPRDannexin IFormyl peptide receptor 1--Pubmed
HPRDannexin Itransglutaminase 2--Pubmed
HPRDannexin Itransglutaminase 2--Pubmed
HPRDannexin IS100 calcium binding protein A11--Pubmed
HPRDannexin IS100 calcium binding protein A11--Pubmed

Recent Publications on ANXA1:

Pubmed Logo
Enhanced neutrophil expression of annexin-1 in coronary artery disease.
The systemic inflammatory activity in patients with stable coronary artery...
24th October, 2009
Department of Biomedicine, School of Health and Medical Sciences, Orebro Metabolism. 2009 Oct 20.
DOI Direct Link
Eicosanoid release is increased by membrane destabilization and CFTR inhibition in Calu-3 cells.
The antiinflammatory protein annexin-1 (ANXA1) and the adaptor S100A10...
23rd October, 2009
INSERM, U845, Universite Paris Descartes, Faculte de Medecine Paris PLoS One. 2009 Oct 22;4(10):e7116.
DOI Direct Link
Proteomics analysis of regenerating amphibian limbs: changes during the onset of regeneration.
During amphibian epimorphic limb regeneration, local injury produces...
20th October, 2009
Indiana University Center for Regenerative Biology and Medicine, Indiana Int J Dev Biol. 2009;53(7):955-69.
DOI Direct Link
Expression of annexin A1 mRNA in peripheral blood from oral squamous cell carcinoma patients.
Several studies have been suggesting annexin A1 protein as an active...
17th October, 2009
Nanobiotechnology Laboratory, Institute of Genetics and Biochemistry, Oral Oncol. 2009 Oct 13.
DOI Direct Link
Identifying apoptosis-evasion proteins/pathways in human hepatoma cells via induction of cellular hormesis by UV irradiation.
Evading apoptosis is pivotal in both of carcinogenesis and resistance to...
9th October, 2009
Chang Gung Memorial J Proteome Res. 2009 Aug;8(8):3977-86.
DOI Direct Link

View more research publications.

BioNews Results for ANXA1

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Glucocorticoid-stimulated, transcription-independent release of annexin A1 by cochlear Hensen cells
Laboratory Investigation:  Nov 13 2009 8:31PM Matching: anxa1

Clinical Trials:

Clinical Trials Logo
Study the Expression of Annexin A1 and Its Potential Usage as a Prognostic Marker in Oral Cancer

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7115265 Four genetic tumor markers specific for human glioblastoma
7153501 Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith

View more patents.

ANXA1 results (if any) from reagent suppliers

Google CSE Logo
ANXA1 antibody, ANXA1 (annexin A1) Antibody, Rabbit Polyclonal ...
Buy quality rabbit ANXA1 antibody (interacts with human), anti-ANXA1, ... Annexin A1, isoform CRA_a; ANXA1 protein; Annexin I; Annexin A1, Q5TZZ9_HUMAN.
http://www.genwaybio.com/product_info.php?products_id=42792...

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Annexin A1 Antibody ANXA1
Annexin A1 antibody was raised against a synthetic peptide of Annexin A1. ,
http://www.prosci-inc.com/shop/catalog1/Annexin-A1-Antibody-...

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Annexin 1 (ANXA-1, Ac 2-12)
Peptides , Annexin , Annexin 1 (ANXA-1, Ac 2-12); This acetylated peptide is an amino-terminus fragment of Annexin 1 (ANXA1). ANXA1, previously referred to ...
http://www.anaspec.com/products/product.asp?id=30516...

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Annexin A1 (MRQ-3)
Anti-Annexin A1 (ANXA 1) is a mouse monoclonal antibody from tissue ... kaemia by immunocytochemical detection of annexin A1 (ANXA1). Lancet. ...
http://www.cellmarque.com/pdf_files/direct/2038.pdf...

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Annexin I (H-65) Antibody sc-11387
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ANXA1, 301, 9q21.13, NM_000700 ...
http://www.scbt.com/datasheet-11387-annexin-i-h-65-antibody....

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Annexin A1 Antibody
(ANXA1) is the first characterized member of the annexin family of proteins able to bind to cellular membranes in a calcium-dependent manner which promotes ...
http://www.cellsignal.com/pdf/3299.pdf...

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Search Results
Anti-ANXA1 antibody produced in rabbit (2). HPA011271, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous ...
http://www.sigmaaldrich.com/catalog/Lookup.do?D7=0&D10=p35&N...

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