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H2AFZ


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Symbol:H2AFZ
Name(s):H2A histone family, member Z
Type:protein-coding
Organism:Homo sapiens
Synonyms:H2A.z, H2A/z, H2AZ, MGC117173
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17636032 Monoubiquitylation of H2A.z distinguishes its association with euchromatin or facultative heterochromatin.
17671089 Upon DNA damage, histone H2A.Z is first evicted from the p21 promoter, followed by the recruitment of the Tip60 histone acetyltransferase to activate p21 transcription.
17194760 identify the essential histone variant H2A.Z as a new structural component of the centromere
16809769 neither H2AZ itself nor other features of the H2AZ-containing nucleosome spread to the neighboring nucleosomes in vivo, arguing against a role for H2AZ as a self-perpetuating epigenetic mark
15878876 chromatin remodeling at the c-myc gene involves the local exchange of histone H2A.Z

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDH2AZ histoneinner centromere protein antigens 135/155kDa--Pubmed
HPRDH2A histone family, member ZINCENP--Pubmed
HPRDH2A histone family, member ZH2A histone family, member Z--Pubmed

Recent Publications on H2AFZ:

Pubmed Logo
Gene Expression in Mouse Preimplantation Embryos Affected by Apoptotic Inductor Actinomycin D.
The aim of this study was to test the effect of actinomycin D on the...
16th July, 2009
Institute of Animal Physiology, Slovak Academy of Sciences. J Reprod Dev. 2009 Jul 14.
Cross-species hybridization of woodchuck hepatitis viral infection-induced woodchuck hepatocellular carcinoma using human, rat and mouse oligonucleotide microarrays.
BACKGROUND AND AIM: We aimed to evaluate the transcriptional...
3rd July, 2009
Department of Biomedical Engineering, Case Western Reserve University, J Gastroenterol Hepatol. 2009 Apr;24(4):605-17. Epub 2008 Oct 21.
DOI Direct Link
Bovine ooplasm partially remodels primate somatic nuclei following somatic cell nuclear transfer.
Interspecies somatic cell nuclear transfer (iSCNT) has the potential to...
27th May, 2009
Michigan State University, East Lansing, 48824, USA. Cloning Stem Cells. 2009 Mar;11(1):187-202.
DOI Direct Link
Alcohol trait and transcriptional genomic analysis of C57BL/6 substrains.
C57BL/6 inbred mice have been widely used as research models; however,...
17th January, 2009
Waggoner Center for Alcohol and Addiction Research, University of Texas at Genes Brain Behav. 2008 Aug;7(6):677-89. Epub 2008 Apr 7.
DOI Direct Link
Expression profiles of the pluripotency marker gene POU5F1 and validation of reference genes in rabbit oocytes and preimplantation stage embryos.
BACKGROUND: The surge in the number of gene expression studies and...
11th November, 2008
Genetic Reprogramming Group, Agricultural Biotechnology Centre, Szent BMC Mol Biol. 2008 Jul 28;9:67.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7465542 Methods and compositions for determining risk of treatment toxicity
7447594 Molecular cardiotoxicology modeling
7426441 Methods for determining renal toxins
7415358 Molecular toxicology modeling
7251568 Methods and compositions for regulating bone and cartilage formation

View more patents.

H2AFZ results (if any) from reagent suppliers

Google CSE Logo
Histone H2A.Z/H2A.F/Z (FL-128) Antibody sc-67218
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, H2AFZ, 3015, 4q23, NM_002106 ...
http://www.scbt.com/datasheet-67218-histone-h2a-z-h2a-f-z-fl...

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Histone H2A.Z/H2A.F/Z (FL-128) Antibody sc-67218
Souris, H2afz, 51788, 3 G3, P0C0S6, Non disponible. Souris, H2afv, 77605, 11 A1, Q3THW5, Non disponible. Produits disponibles. Nom du produit, Référence ...
http://www.scbt.com/fr/datasheet-67218-histone-h2a-z-h2a-f-z...

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Histone H2A.Z/H2A.F/Z (FL-128) Antibody sc-67218
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, H2AFZ, 3015, 4q23, NM_002106 · P0C0S5
...
http://www.scbt.com/ja/datasheet-67218-histone-h2a-z-h2a-f-z...

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Histone H2A.Z/H2A.F/Z (FL-128) Antibody sc-67218
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, H2AFZ, 3015, 4q23, NM_002106 · P0C0S5 ...
http://www.scbt.com/de/datasheet-67218-histone-h2a-z-h2a-f-z...

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