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HADHB


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Gene DB Home
Symbol:HADHB
Name(s):hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
Type:protein-coding
Organism:Homo sapiens
Synonyms:ECHB, MGC87480, MSTP029, TP-BETA
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17199921 The common disease causing mutation of G1528C in MTP gene in caucasian in probably not a common mutation in Chinese Han people in Beijing.
14630990 Both alpha- and beta-subunit mutations result in TFP complex instability, demonstrating that the mechanism of disease is the same in alpha- or beta-mutation-derived disease and explaining the biochemical and clinical similarities.
12933794 HADHB trifunctional enzyme, human renin, and poly(C)-binding protein are novel renin mRNA-binding proteins that target a cis-element in the 3'-UTR of renin mRNA and regulate renin production

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDamyloid beta A4 protein precursor, isoform aHydroxyacyl dehydrogenase, subunit B--Pubmed
HPRDmitochondrial trifunctional protein, beta subunit precursorTNNI3 interacting kinase isoform b--Pubmed

Recent Publications on HADHB:

Pubmed Logo
Two novel HADHB gene mutations in a Korean patient with mitochondrial trifunctional protein deficiency.
Mitochondrial trifunctional protein (MTP) is a heterocomplex composed of 4...
3rd November, 2009
Department of Laboratory Medicine & Genetics, Sungkyunkwan University Ann Clin Lab Sci. 2009 Fall;39(4):399-404.
Clinical and molecular aspects of Japanese patients with mitochondrial trifunctional protein deficiency.
Mitochondrial trifunctional protein (MTP) deficiency is a rare inherited...
25th August, 2009
Department of Pediatrics, Shimane University, Faculty of Medicine, Izumo, Mol Genet Metab. 2009 Jul 23.
DOI Direct Link
Sex differences in global mRNA content of human skeletal muscle.
Women oxidize more fat as compared to men during endurance exercise and...
23rd July, 2009
Department of Medical Sciences, McMaster University, Hamilton, Ontario, PLoS One. 2009 Jul 22;4(7):e6335.
DOI Direct Link
Underlying mechanisms of pharmacology and toxicity of a novel PPAR agonist revealed using rodent and canine hepatocytes.
Marked species-specific responses to agonists of the peroxisome...
31st July, 2007
Department of Investigative Toxicology, Lilly Research Laboratories, Toxicol Sci. 2007 Apr;96(2):294-309. Epub 2007 Jan 25.
DOI Direct Link
ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit.
Using the metabolomics-guided screening coupled to...
3rd April, 2007
Institute of Biomedical Sciences, Academia Sinica, Nankang, Taipei, Hum Mol Genet. 2006 Dec 15;15(24):3569-77. Epub 2006 Nov 20.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7601532 Microarray for predicting the prognosis of neuroblastoma and method for predicting the prognosis of neuroblastoma
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7041814 Nucleic acid and amino acid sequences relating to Enterobacter cloacae for diagnostics and therapeutics
7094568 Method for producing proteins tagged at the N- or C-terminus

View more patents.

HADHB results (if any) from reagent suppliers

Google CSE Logo
HADHB antibody (ab10093) | Abcam
Goat polyclonal to HADHB. The HADHA and HADHB genes encode the alpha and beta subunits of the mitochondrial trifunctional protein, respectively.
http://www.abcam.com/HADHB-antibody-ab10093.html...

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HADH Antibody / HADH Antibodies
HADHB (S-16) Antibody, sc-55661, goat IgG, N-terminus (h), WB, IP, IF, ELISA, m, r, h, cow and pig ... HADHB shRNA Plasmid (h): sc-62435-SH. HADHB shRNA (h) ...
http://www.scbt.com/table-hadh.html...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
18-202-335586, HADHB Related Product Names: - HADHB; - Mitochondrial trifunctional protein, beta subunit; N/A, IgG Polyclonal ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=H...

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HADHB siRNA (h) sc-62435
Click here for details. suitable control antibody: HADHB (S-16): sc-55661; sqRT- PCR Primer also available: HADHB (h)-PR: sc-62435, 20 µl ...
http://www.scbt.com/ko/datasheet-62435-hadhb-sirna-h.html...

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Abcam antibodies and reagents product map
... Ganglioside asialo GM2 antibodies (2) · Gpihbp1 antibodies (2) · HADHA antibodies (1) · HADHB antibodies (1) · HADHB proteins and peptides (1) ...
http://www.abcam.com/index.html?c=2105...

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HADHB (S-16) Antibody sc-55661
HADHB (S-16) 抗体sc-55661 HADHB (S-16) Antibody sc-55661.
http://www.scbt.com/zh/datasheet-55661-hadhb-s-16-antibody.h...

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HADHB (S-16) Antibody sc-55661
HADHB (S-16) Anticorpo sc-55661 HADHB (S-16) Antibody sc-55661.
http://www.scbt.com/pt/datasheet-55661-hadhb-s-16-antibody.h...

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