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HAS1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15794859 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18199543 |
HAS1 regulates bladder cancer growth and progression by modulating hyaluronic acid synthesis and hyaluronic acid receptor levels. |
| 17922656 |
Treatment of fibroblasts with growth factors up-regulated HAS gene expression and increased HAS enzymes and HA production. |
| 17904513 |
HAS1 captured in this pull-down approach is readily immunodetected by Western blot analysis using appropriate antibodies. |
| 17611197 |
Interleukin-1beta stimulation resulted in induction of HAS1 and HAS2 transcription but did not induce phenotypic differentiation or induce hyaluronan coat assembly |
| 14636845 |
Expression of each hyaluronan synthase isoform is regulated differently by growth factors and cytokines in vascular endothelial cells. Expressed in proliferative membranes from proliferative vitreoretinal diseases. May affect progression of diseases. |
| 12720129 |
Expression of HAS1 in Waldenstrom's macroglobulinemia. Variants of HAS1 synthesize the intracellular HA ligand for RHAMM and may contribute to genetic instability in Waldenstrom's macroglobulinemia. |
| 11790779 |
hyaluronan synthase expression in prostate adenocarcinoma cells |
| 12239172 |
characterization of expression and hyaluronan synthesis in bone marrow mesenchymal progenitor cells: predominant expression of mRNA and up-regulated hyaluronan synthesis in bone marrow cells derived from multiple myeloma patients |
| 15870928 |
Increased HAS1 expression and an increase in serum hyaluronan in endometrial cancer may be associated with disease progression through myometrial invasion and lymph-vascular space involvement | →View more information from publications. |
Recent Publications on HAS1: |  |
Mycobacteria exploit host hyaluronan for efficient extracellular replication.
In spite of the importance of hyaluronan in host protection against... | 31st October, 2009
| Department of Bacteriology, Osaka City University Graduate School of
| PLoS Pathog. 2009 Oct;5(10):e1000643. Epub 2009 Oct 30.
DOI Direct Link |
Modulation of hyaluronan synthase activity in cellular membrane fractions.
Hyaluronan (HA), the only non-sulfated glycosaminoglycan, is involved in... | 10th September, 2009
| Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita
| J Biol Chem. 2009 Oct 30;284(44):30684-94. Epub 2009 Sep 8.
DOI Direct Link |
Pro- and anti-inflammatory cytokines increase hyaluronan production by rat synovial membrane in vitro.
Synovial membrane consists of fibroblasts and macrophages forming the... | 3rd September, 2009
| Department of Histology and Embryology, Medical University of Warsaw,
| Int J Mol Med. 2009 Oct;24(4):579-85.
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Aberrant splice variants of HAS1 (Hyaluronan Synthase 1) multimerize with and modulate normally spliced HAS1 protein: a potential mechanism promoting human cancer.
Most human genes undergo alternative splicing, but aberrant splice forms... | 2nd September, 2009
| Department of Oncology, University of Alberta and Cross Cancer Institute,
| J Biol Chem. 2009 Jul 10;284(28):18840-50. Epub 2009 May 18.
DOI Direct Link |
Synthesis of hyaluronan in oesophageal cancer cells is uncoupled from the prostaglandin-cAMP pathway.
BACKGROUND AND PURPOSE: Cyclooxygenase-2 (COX2) and hyaluronic acid (HA)... | 15th August, 2009
| Institut fur Pharmakologie, Universitatsklinikum Essen, Universitat
| Br J Pharmacol. 2009 May;157(2):234-43. Epub 2009 Mar 26.
DOI Direct Link |
→View more research publications. |
HAS1 results (if any) from reagent suppliers | 
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HAS Antibody / HAS Antibodies
HAS1 (C-14) Antibody, sc-23145, goat IgG, C-terminus (h), WB, IP, IF, ELISA, m, r, h. HAS1 (G-17) Antibody, sc-34021, goat IgG, internal (h), WB, IF, ELISA ...
http://www.scbt.com/table-has.html...
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Recombinant
Mammalian HA is synthesized by one of three distinct HA synthases (HAS1, 2, and 3), ... greater than 2000 kDa, HAS-1 and HAS-3 produce HA with a size ...
http://www.rndsystems.com/pdf/GLR003.pdf...
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HAS1 siRNA (h) sc-40690
Click here for details. suitable control antibody: HAS1 (C-14): sc-23145; sqRT- PCR Primer also available: HAS1 (h)-PR: sc-40690-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-40690-has1-sirna-h.html...
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Hyaluronan (HA) & HA-binding Proteins - R&D Systems
Mammalian hyaluronan is synthesized by one of three distinct hyaluronan synthases (HAS1, 2, and 3), which produce HA polymers with different chain
lengths ...
http://www.rndsystems.com/molecule_group.aspx?g=1010&r=1...
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HAS1 (C-14) Antibody sc-23145
HAS1 (C-14) Anticuerpo sc-23145 HAS1 (C-14) Antibody sc-23145.
http://www.scbt.com/es/datasheet-23145-has1-c-14-antibody.ht...
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Trevigen Final Layout
Human homologs of Schizosaccharomyces pombe Rad1, Has1, and Rad9 form a DNA damage-responsive protein complex. J. Biol. Chem. 274:567-570. ...
http://www.trevigen.com/MarketingFlyers/OnlineCat.pdf...
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