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HAS3


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Gene DB Home
Symbol:HAS3
Name(s):hyaluronan synthase 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
14636845 Expression of each hyaluronan synthase isoform is regulated differently by growth factors and cytokines in vascular endothelial cells. Expressed in proliferative membranes from proliferative vitreoretinal diseases. May affect progression of diseases.
11790779 hyaluronan synthase expression in prostate adenocarcinoma cells
14566823 Hyaluronan and HAS3 function in the growth and progression of colon carcinoma
16564133 mRNA for HAS1 is undetectable but HAS3 mRNA can be readily detected in freshly isolated CD133+ as well as in CD133- umbilical cord blood (UCB) cells. mRNA for HAS2 can only be detected in CD133+ progenitor cells.
16786194 The aim of this study was to evaluate how TNF-alpha, IFN-gamma,IL-1beta, and exposition to oxidative stress may modulate HAS activities in normal human skin fibroblasts.

Recent Publications on HAS3:

Pubmed Logo
Mycobacteria exploit host hyaluronan for efficient extracellular replication.
In spite of the importance of hyaluronan in host protection against...
31st October, 2009
Department of Bacteriology, Osaka City University Graduate School of PLoS Pathog. 2009 Oct;5(10):e1000643. Epub 2009 Oct 30.
DOI Direct Link
Regenerative effects of basic fibroblast growth factor on extracellular matrix production in aged rat vocal folds.
OBJECTIVES: We investigated acute changes in extracellular matrix (ECM)...
9th October, 2009
Department of Otolaryngology, Vanderbilt University Bill Wilkerson Center Ann Otol Rhinol Laryngol. 2009 Aug;118(8):559-64.
Inhibition of HA synthase 3 mRNA expression, with a phosphodiesterase 3 inhibitor, blocks lung injury in a septic ventilated rat model.
Low-molecular-weight hyaluronan produced by hyaluronan synthase 3 (HAS3)...
3rd October, 2009
Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts Lung. 2009 Aug;187(4):233-9. Epub 2009 Jul 2.
DOI Direct Link
Modulation of hyaluronan synthase activity in cellular membrane fractions.
Hyaluronan (HA), the only non-sulfated glycosaminoglycan, is involved in...
10th September, 2009
Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita J Biol Chem. 2009 Oct 30;284(44):30684-94. Epub 2009 Sep 8.
DOI Direct Link
Pro- and anti-inflammatory cytokines increase hyaluronan production by rat synovial membrane in vitro.
Synovial membrane consists of fibroblasts and macrophages forming the...
3rd September, 2009
Department of Histology and Embryology, Medical University of Warsaw, Int J Mol Med. 2009 Oct;24(4):579-85.

View more research publications.

Clinical Trials:

Clinical Trials Logo
Study of Neoadjuvant Chemotherapy With Selective Radiotherapy in Patients With Intermediate-Risk Cancer Rectum Defined by Magnetic Resonance Imaging (MRI)

Patents:

Patents logo
US Patent No.Title
7604973 DNA encoding hyaluronan synthase from Pasteurella multocida and methods of use
7087413 Hyaluronan synthase gene and uses thereof
7060469 Polymer grafting by polysaccharide synthases
7060466 Methods of producing hyaluronic acid using a recombinant hyaluronan synthase gene
7029880 Streptococcus equisimilis hyaluronan synthase gene and expression thereof in Bacillus subtilis

View more patents.

HAS3 results (if any) from reagent suppliers

Google CSE Logo
HAS Antibody / HAS Antibodies
HAS3 (E-15) Antibody, sc-34204, goat IgG, cytoplasmic (h), WB, IF, ELISA, m, r, h. HAS3 (H-64) Antibody, sc-66917, rabbit IgG, 124-187 (h), WB, IP, IF, ...
http://www.scbt.com/table-has.html...

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HAS3 antibodies: Stem Cells > Hematopoietic Progenitors > Surface ...
HAS3 antibodies. ... HAS3 antibodies. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication. ab32231 · HAS3 antibody ...
http://www.abcam.com/index.html?t=125797&pt=1&c=3568&ei=&mu=...

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HAS Antibody / HAS Antibodies
HAS3 (E-15) 抗体, sc-34204, goat IgG, cytoplasmic (h), WB, IF, ELISA, m, r, h. HAS3 (H-64) 抗体, sc-66917, rabbit IgG, 124-187 (h), WB, IP, IF, ELISA, m, r,
...
http://www.scbt.com/ja/table-has.html...

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HAS3 proteins and peptides: Signal Transduction > Cytoskeleton ...
HAS3 proteins and peptides. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication. ab32230 · HAS3 peptide ...
http://www.abcam.com/index.html?t=125797&pt=2&c=2230&ei=&mu=...

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HAS3 (H-64) Antibody sc-66917
HAS3 siRNA shRNA (h) Lentiviral Particles, sc-45295-V, 200 µl ... Western blot analysis of HAS3 expression in non-transfected 293T: sc-117752 (A), ...
http://www.scbt.com/ko/datasheet-66917-has3-h-64-antibody.ht...

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Anti-Human α2 Integrin-R-phycoerythrin (R-PE)
Mouse Anti-Human α2 Integrin (Clone HAS3) recognizes an epitope on Human α2 Integrin. This monoclonal antibody was purified using multi-step affinity ...
http://www.leinco.com/Monoclonal-Antibody/Anti-Human-Alpha2-...

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Integrin α2 (HAS-3) Antibody sc-53352
Integrin α2 (HAS-3) 抗体 sc-53352 Integrin α2 (HAS-3) Antibody sc-53352.
http://www.scbt.com/ja/datasheet-53352-integrin-alpha2-has-3...

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