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HBG1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17976188 |
analysis of a model for dynamic post-transcriptional control of gamma-globin gene expression, through modulation of the stability of its encoding mRNA |
| 17612629 |
data provide important clues for identifying and validating trans-activators that activate the gamma-globin gene in fetuses, and trans-acting factors involved in silencing the gamma-globin gene in adults |
| 11960008 |
Developmental specificity of recruitment of TBP to the TATA box of the human gamma-globin gene |
| 15831451 |
Direct repeat element in the promoter region of the gamma-globin gene autonomously mediates definitive stage-specific gene silencing. |
| 12393499 |
Apicidin activates the A gamma globin gene promoter. Activation of the Agamma-globin promoter by apicidin could be inhibited by p38 inhibitor SB203580 |
| 16849648 |
A novel gamma-globin-inducing short-chain fatty acid derivative (SCFAD), RB7, which was identified through computational modeling, produced a 6-fold induction in a reporter assay. |
| 14645237 |
human gamma-globin gene expression is developmentally regulated by the CCAAT box |
| 12093744 |
DRED binds with high affinity to DR1 sites in the human epsilon & gamma globin promoters, but the adult beta-globin promoter has no DR1 element. An HPFH mutation in a DR1 site causes elevated gamma-globin transcription & reduces TR2/TR4 binding in vitro. |
| 14649320 |
in an Albanian family, two mutations of the gamma-globin promoter (for both HBG1 and HBG2) are assoicated in trans with a beta thal point mutation, that results in increased levels of HbF |
| 16631597 |
Together, these results show that the cAMP pathway blocks gamma-globin gene expression in K562 cells by increasing c-Myb expression. | →View more information from publications. |
Recent Publications on HBG1: |  |
Multiplex ligation-dependent probe amplification screening of isolated increased HbF levels revealed three cases of novel rearrangements/deletions in the beta-globin gene cluster.
Summary Investigations of naturally occurring mutations, such as the... | 8th October, 2009
| Department of Laboratory Medicine and Genetics, Samsung Medical Centre,
| Br J Haematol. 2009 Oct 5.
DOI Direct Link |
The Hellenic type of nondeletional hereditary persistence of fetal hemoglobin results from a novel mutation (g.-109G>T) in the HBG2 gene promoter.
Nondeletional hereditary persistence of fetal hemoglobin (nd-HPFH), a rare... | 25th July, 2009
| Department of Biology, School of Medicine, University of Thessaly,
| Ann Hematol. 2009 Jun;88(6):549-55. Epub 2008 Dec 3.
DOI Direct Link |
Identification of four novel developmentally regulated gamma hemoglobin mRNA isoforms.
OBJECTIVE: In the course of developing assays for the molecular prediction... | 20th February, 2009
| Graduate Program in Biomolecular Science, University of Central Florida,
| Exp Hematol. 2009 Feb;37(2):285-93. Epub 2008 Dec 6.
DOI Direct Link |
A mechanism for Ikaros regulation of human globin gene switching.
The human beta globin locus consists of an upstream LCR and functional... | 28th June, 2008
| Institute for Molecular Bioscience, Queensland Bioscience Precinct,
| Br J Haematol. 2008 May;141(3):398-406. Epub 2008 Mar 3.
DOI Direct Link |
A novel locus for maternally inherited human gingival fibromatosis at chromosome 11p15.
Human isolated gingival fibromatosis is an oral disorder characterized by... | 29th September, 2007
| Health Science Institute, Shanghai Institutes for Biological Sciences,
| Hum Genet. 2007 Mar;121(1):113-23. Epub 2006 Oct 31.
DOI Direct Link |
→View more research publications. |
HBG1 results (if any) from reagent suppliers | 
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Hemoglobin antibody, Hemoglobin [901] Antibody, Mouse Monoclonal ...
Hemoglobin antibody; Hemoglobin; 3039; HBA1; 141800; Q3MIF5; CD31; MGC126895; MGC126897; 3043; HBB; 141900; P68871; CD113t-C; HBD; hemoglobin; 3047; HBG1; ...
http://www.genwaybio.com/product_info.php?products_id=193038...
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fetal hemoglobin antibody (ab19364) | Abcam
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver , spleen and bone marrow. Two gamma chains together with two alpha cha...
http://www.abcam.com/fetal-hemoglobin-antibody-ab19364.html...
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Hemoglobin γ (51-7) Antibody sc-21756
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, HBG1, 3047, 11p15.4, NM_000559 ...
http://www.scbt.com/datasheet-21756-hemoglobin-gamma-51-7-an...
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Panorama® Antibody Array - Signal Transduction
HBG1. hemoglobin, gamma A. 3047 · HCLS1. hematopoietic cell-specific Lyn substrate 1. 3059 · HIF1A. hypoxia-inducible factor 1, alpha subunit ...
http://www.sigmaaldrich.com/life-science/cell-biology/protei...
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Hemoglobin β/γ/δ (H-76) Antibody sc-21006
Human, HBG1, 3047, 11p15.4, NM_000559 · P69891 · 142200. Mouse, Hbb-b1, 15129, 7 E3, P02088, N/A. Mouse, 15130, N/A. Mouse, Hbb-y, 15135, 7 E3, P02104 ...
http://www.scbt.com/datasheet-21006-hemoglobin-beta-gamma-de...
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Hemoglobin α/β/γ (901) Antibody sc-58266
Human, HBG1, 3047, 11p15.4, NM_000559 · P69891 · 142200. 주문정보. 제품명, 카탈로그 번호, 단위, 가격, 수량, 관심상품. Hemoglobin α/β/γ (901), sc-58266 ...
http://www.scbt.com/ko/datasheet-58266-hemoglobin-alpha-beta...
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Hemoglobin β/γ/δ (H-76) Antibody sc-21006
ヒト, HBG1, 3047, 11p15.4, NM_000559 · P69891 · 142200. マウス, Hbb-b1, 15129, 7 E3, P02088, N/A. マウス, 15130, N/A. マウス, Hbb-y, 15135, 7 E3, P02104 ...
http://www.scbt.com/ja/datasheet-21006-hemoglobin-beta-gamma...
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