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HCCS


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Gene DB Home
Symbol:HCCS
Name(s):holocytochrome c synthase (cytochrome c heme-lyase)
Type:protein-coding
Organism:Homo sapiens
Synonyms:CCHL, DKFZp779I1858, MCOPS7
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17893649 Missense mutation p.E159K of HCCS, leading to loss-of-function of encoded holocytochrome c-type synthase, in female with microphthalmia of both eyes and bilateral sclerocornea may suggest HCCS as candidate for severe ocular manifestations.
17033964 mutant proteins (R217C and Delta 197-268) were unable to complement a Saccharomyces cerevisiae mutant deficient for the HCCS orthologue Cyc3p, in contrast to wild-type HCCS
12444108 Through the study of genetically engineered mice, the loss of HCCS is demonstrated to cause the male lethality of microphthalmia with linear skin defects (MLS) syndrome.

Recent Publications on HCCS:

Pubmed Logo
Single-session Combined Therapy with Chemoembolization and Radiofrequency Ablation in Hepatocellular Carcinoma Less than or Equal to 5 cm: A Preliminary Study.
PURPOSE: To evaluate the efficacy and safety of a single-session combined...
3rd November, 2009
Department of Radiology, Seoul National University College of Medicine, J Vasc Interv Radiol. 2009 Oct 29.
DOI Direct Link
Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene.
Hippo-Lats-Yorkie signaling regulates tissue overgrowth and tumorigenesis...
3rd November, 2009
Department of Molecular Biology, Massachusetts General Hospital, Boston, Cancer Cell. 2009 Nov 6;16(5):425-38.
DOI Direct Link
De novo hepatocellular carcinoma in a liver graft with sustained hepatitis C virus clearance after living donor liver transplantation.
The occurrence of de novo hepatocellular carcinoma (HCC) after liver...
31st October, 2009
Department of Surgery and Science, Graduate School of Medical Sciences, Liver Transpl. 2009 Oct 28;15(11):1412-1416.
DOI Direct Link
Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma.
Abstract Background: Deleted in liver cancer (DLC) is a family of tumour...
31st October, 2009
Liver Cancer and Hepatitis Research Laboratory and SH Ho Foundation Liver Int. 2009 Oct 27.
DOI Direct Link
CKS1B Overexpression Implicates Clinical Aggressiveness of Hepatocellular Carcinomas but Not p27(Kip1) Protein Turnover: an Independent Prognosticator with Potential p27 (Kip1)-Independent Oncogenic Attributes?
BACKGROUND: Through data mining the Stanford Microarray Database, the...
30th October, 2009
Department of Surgery, Yuan's General Hospital, Kaohsiung, Taiwan. Ann Surg Oncol. 2009 Oct 29.
DOI Direct Link

View more research publications.

Press Releases on HCCS:

BioPortfolio Logo
HCCS Celebrates Sixth Annual National Health Care Compliance Training Week 8th October, 2009 Health Care Compliance Strategies, Inc.

JERICHO, N.Y., Oct. 8 /PRNewswire/ -- Health Care Compliance Strategies, Inc. (HCCS) announced today that it will celebrate National Health Care Compliance Training Week, October

Managing Conflict of Interest Disclosures Simplified for Healthcare Organizations 21st April, 2009 Health Care Compliance Strategies, Inc.

HCCS Releases New COI Management and Tracking Tool

JERICHO, N.Y., April 21 /PRNewswire/ -- HCCS (Health Care Compliance Strategies, Inc.), the leading provider of online

BioNews Results for HCCS

: RSS Logo
BioPortfolio Logo
EFNA1 ligand and its receptor EphA2: Potential biomarkers for hepatocellular carcinoma
MDLinx:  Nov 9 2009 10:38AM Matching: hccs
What Is the Optimal Timing of Hepatitis C Antiviral Therapy Before and After Liver Transplantation? Presented
Doctors Guide:  Nov 4 2009 10:18PM Matching: hccs
HCCS celebrates 6th Annual National Health Care Compliance Training Week
Chiropractic Economics:  Oct 13 2009 3:53AM Matching: hccs
National Health Care Compliance Training Week to educate healthcare organizations
News-Medical.Net:  Oct 9 2009 11:19AM Matching: hccs
HCCS Celebrates Sixth Annual National Health Care Compliance Training Week
Individual.com:  Oct 8 2009 4:28PM Matching: hccs
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Comparison Study of Transarterial Chemoembolization and Percutaneous Ethanol Injection for Multiple, Small HCCs

Patents:

Patents logo
US Patent No.Title
6210939 Recombinant adenoviral vector and methods of use
6596910 Process for the manufacture of fluorocarbons
6610250 Apparatus using halogenated organic fluids for heat transfer in low temperature processes requiring sterilization and methods therefor
6630610 Method of producing fluorinated organic compounds
6664246 Pharmaceutical composition

View more patents.

HCCS results (if any) from reagent suppliers

Google CSE Logo
HCCS siRNA (h) sc-91122
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: HCCS ...
http://www.scbt.com/datasheet-91122-hccs-sirna-h.html...

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Glypican-3 (GPC3) in cancer
In a study of 120 liver needle biopsy specimens, including 46 from cirrhotic livers and 74 hepatocellular carcinomas (HCCs), that were immunohistochemically
...
http://www.exalpha.com/GPC3.html...

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HCCS Antibody / HCCS Antibodies
HCCS Antibody / HCCS Antibodies. ... HCCS specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-hccs.html...

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LAB VISION - NeoMarkers QUARTERLY NEWSLETTER
characterized primary HCC xenograftsto screen novel compounds and improve the ... Eight primary HCCs were obtained intra-operatively during liver resection
...
http://www.labvision.com/pdf/newsletter5.pdf...

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Abcam antibodies and reagents product map
... Cytochrome p450 2C19 proteins and peptides (1) · Cytochrome p450 2J2 antibodies (3) · HCCS antibodies (2) · HNF4 antibodies (7) · PTGIS antibodies (3
) ...
http://www.abcam.com/index.html?c=253...

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Abcam antibodies and reagents product map
... HADHSC antibodies (4) · HADHSC proteins and peptides (1) · HBLD1 antibodies (1) · HBLD2 antibodies (1) · HCCS antibodies (2) · HIBADH antibodies (3) ...
http://www.abcam.com/index.html?cl=2105&pageconfig=productma...

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