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HFE


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Symbol:HFE
Name(s):hemochromatosis
Type:protein-coding
Organism:Homo sapiens
Synonyms:HFE1, HH, HLA-H, MGC103790, dJ221C16.10.1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18199861 Observational study of gene-disease association. (HuGE Navigator)
18201677 Observational study of genetic testing. (HuGE Navigator)
18263976 Observational study of genotype prevalence. (HuGE Navigator)
18273820 Observational study of gene-disease association. (HuGE Navigator)
18276042 Observational study of gene-disease association. (HuGE Navigator)
18284459 Observational study of genotype prevalence. (HuGE Navigator)
18300942 Observational study of gene-disease association. (HuGE Navigator)
18317757 Observational study of genotype prevalence. (HuGE Navigator)
18325820 Observational study of gene-disease association. (HuGE Navigator)
18327584 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDBeta 2 microglobulinhemochromatosis protein isoform 1 precursor--Pubmed
HPRDbeta-2-microglobulin precursorHemochromatosis protein--Pubmed
HPRDHemochromatosis proteintransferrin receptor 2--Pubmed
HPRDhemochromatosis protein isoform 1 precursorTransferrin receptor 2--Pubmed
HPRDhemochromatosis protein isoform 1 precursortransferrin receptor--Pubmed
HPRDhemochromatosis protein isoform 1 precursortransferrin receptor--Pubmed

Recent Publications on HFE:

Pubmed Logo
A common SNP near BMP2 is associated with severity of the iron burden in HFE p.C282Y homozygous patients: A follow-up study.
Background and Objectives. It is now generally admitted that penetrance of...
3rd November, 2009
IRD - UR010, Paris, France. Blood Cells Mol Dis. 2009 Oct 29.
DOI Direct Link
Lack of association of C282Y and H63D mutations in the hemochromatosis (HFE) gene with diabetes mellitus type 2 in a case-control study of women in Brazil.
Hereditary hemochromatosis is one of the most common autosomal recessive...
31st October, 2009
Faculdade de Farmacia, Universidade Federal de Minas Gerais, Belo Genet Mol Res. 2009 Oct 27;8(4):1285-91.
DOI Direct Link
Effect of iron supplementation on iron status during the first week after blood donation.
Introduction Frequent blood donations may lead to a negative iron balance....
31st October, 2009
Institute of Medicine, University of Bergen, Bergen, Norway. Vox Sang. 2009 Oct 28.
DOI Direct Link
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.
Measurements of erythrocytes within the blood are important clinical...
29th October, 2009
National Human Genome Research Institute, Division of Intramural Research, Nat Genet. 2009 Nov;41(11):1191-8. Epub 2009 Oct 11.
DOI Direct Link
HLA-E and HLA-E-bound peptides: recognition by subsets of NK and T cells.
In humans, major histocompatibility complex (MHC) class I molecules...
29th October, 2009
Dipartimento di Medicina Sperimentale and Centro di Eccellenza per le Curr Pharm Des. 2009;15(28):3336-44.

View more research publications.

BioNews Results for HFE

: RSS Logo
BioPortfolio Logo
FMC's New High Functionality Excipient - Avicel HFE - 102
Express Pharma:  Oct 26 2009 2:12PM Matching: hfe
Hemochromatosis mutations linked to hypertriglyceridemia
MedWire News:  Oct 15 2009 5:34PM Matching: hfe
Older adults want robots that do more than vacuum, human factors/ergonomics researchers find
Research & Development:  Oct 14 2009 3:03PM Matching: hfe
Iron Regulates The TLR4 Inflammatory Signaling Pathway
Medical News Today:  Oct 7 2009 4:44PM Matching: hfe
Iron regulates the TLR4 inflammatory signaling pathway
PhysOrg.com:  Oct 6 2009 12:51PM Matching: hfe
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Treatment of Hemochromatosis

Patents:

Patents logo
US Patent No.Title
7541323 Sprayable dry wash and wax composition and method of using same
7557438 Cooling mechanism for stacked die package, and method of manufacturing stacked die package containing same
7557797 Mouse-based user interface device providing multiple parameters and modalities
7558699 Control system for centrifugal pumps
7560424 Targeted therapeutic proteins

View more patents.

HFE results (if any) from reagent suppliers

Google CSE Logo
HFE antibody (ab55182) | Abcam
Mouse monoclonal to HFE. Hemochromatosis protein (HFE) is a membrane protein that is similar to MHC class I-type proteins and associates with ...
http://www.abcam.com/HFE-antibody-ab55182.html...

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HFE Antibody / HFE Antibodies
HFE Antibody / HFE Antibodies. ... HFE specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-hfe.html...

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Detecting HFE Mutations in Human Genomic DNA: Student Laboratory ...
The most commonly found mutations in the HFE gene that are associated with the dis- ... The human HFE gene is located on the short arm of Chromosome 6. ...
http://www.promega.com/education/unit002/sm002.0208.pdf...

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HFE (W-24) Antibody sc-133654
rabbit polyclonal IgG, 50 µg/0.5 ml; recommended for detection of HFE of human ... HFE (W-24): sc-133654. Western blot analysis of HFE expression in Hep G2 ...
http://www.scbt.com/datasheet-133654-hfe-w-24-antibody.html...

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ATCC: Catalog Search
The antibody recognizes the HFE portion of the HFE/beta2 heterodimer. HFE is a major histocompatibility complex (MHC) related protein that is mutated in the
...
http://www.atcc.org/ATCCAdvancedCatalogSearch/ProductDetails...

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HFE (44-H) Antibody sc-130375
HFE shRNA (h) Lentiviral Particles, sc-43832-V, 200 µl ... HFE (44-H): sc-130375 . Immunofluorescence staining of methanol-fixed HeLa cells showing membrane ...
http://www.scbt.com/datasheet-130375-hfe-44-h-antibody.html...

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Detecting HFE Mutations in Human Genomic DNA: Instructor's Manual
amplify exons 2 and 4 from the HFE gene and look for restriction ... The most commonly found mutations in the HFE gene that are associated with the dis- ...
http://www.promega.com/education/unit002/im002.0208.pdf...

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