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KCNIP3


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Symbol:KCNIP3
Name(s):Kv channel interacting protein 3, calsenilin
Type:protein-coding
Organism:Homo sapiens
Synonyms:CSEN, DREAM, KCHIP3, MGC18289
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17962406 analysis of calcium-binding properties of EF-hands 3 and 4 of calsenilin
15770150 Calsenilin overexpression in both neurons and reactive astrocytes may play an important role in apoptosis and in Alzheimer's disease pathology.
12217801 apoptosis inducers as diverse as oncoprotein inhibitors and cell death receptor activators trigger Hrk expression via blockade of DREAM in leukemia cells
12837631 calsenilin can be phosphorylated by casein kinase I and that its phosphorylation can be regulated by intracellular calcium.
16177826 DREAM is a Ca2+-dependent repressor of the immune response.
16840549 DREAM plays an important role in human calcitonin gene expression in a Ca(2+)- and cAMP-dependent manner
17102134 interaction of DREAM with GRK6 and GRK2, members of the G protein-coupled receptor kinase family of proteins, and their phosphorylation of DREAM
15086516 The level of intracellular calcium can modulate the nuclear translocation of calsenilin and this process does not involve the direct binding of calcium to calsenilin
12648752 Immunoreactivity of calsenilin in the hippocampus derived from an epilepsy patient is significantly decreased compared with normal brain.
16306395 The downregulation of the regulator of Ca2+ homeostasis NCX3 by Ca2+-regulated DREAM is a striking example of the autoregulatory property of the Ca2+ signal in neurons.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCaspase 3Kv channel interacting protein 3 isoform 1--Pubmed
HPRDcaspase 3 preproproteinCalsenilin--Pubmed
HPRDActive transcription factor CREBKv channel interacting protein 3 isoform 1--Pubmed
HPRDcAMP responsive element binding protein 1 isoform BCalsenilin--Pubmed
HPRDcAMP responsive element modulator isoform aKv channel interacting protein 3 isoform 1--Pubmed
HPRDcAMP responsive element modulator isoform aKv channel interacting protein 3 isoform 1--Pubmed
HPRDPresenilin 1Kv channel interacting protein 3 isoform 1--Pubmed
HPRDPresenilin 2Kv channel interacting protein 3 isoform 1--Pubmed
HPRDpresenilin 2 isoform 1Calsenilin--Pubmed

KCNIP3 results (if any) from reagent suppliers

Google CSE Logo
DREAM (FL-214) Antibody sc-9142
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, KCNIP3, 30818, 2q11.1, NM_001034914,
...
http://www.scbt.com/datasheet-9142-dream-fl-214-antibody.htm...

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DREAM (K-17) Antibody sc-9309
Human, KCNIP3, 30818, 2q11.1, NM_001034914, NM_013434 · Q9Y2W7 · 604662. Mouse, Kcnip3, 56461, 2 F1, P0C092,Q9QXT8, N/A. Mouse, Kcnip2, 80906, 19 C3, Q9JJ69 ...
http://www.scbt.com/datasheet-9309-dream-k-17-antibody.html...

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