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KCNIP2


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Symbol:KCNIP2
Name(s):Kv channel interacting protein 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:DKFZp566L1246, KCHIP2, MGC17241
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12135940 Regulation of Kv4.3 current by KChIP2 splice variants
16177826 KChIP-2 is a Ca2+-dependent repressor of the immune response.
14623880 Kv4.2 and K+ channel-interacting protein 2 make up a complex of Ito channels
15358149 Data show that KChIP1, KChIP2.1, and KChIP2.2 could form homo- as well as hetero-oligomers, and that this oligomerization did not perturb their interaction with Kv4.2 potassium channel.
15498806 Both Kv4.3 and KChIP2 may contribute to epicardial-endocardial gradients in the transient outward current in normal and failing hearts.
12928444 Analysis with chimeric proteins between KChIP2 and NCS-1 reveals that the three regions of KChIP2 are necessary and sufficient for its effective binding to Kv4.3 protein
16820361 the C-terminal domain of Kv4.2 plays a critical role in voltage-dependent activation and functional expression that is mediated by direct interaction between the Kv4.2 C terminus and KChIP2
16951992 The conformational change with metal-bound KChIP4.1 is crucial for its interaction with Kv channel but not for KChIP2.2, and that the Mg2+- and Ca2+-binding properties of KChIP2.2 and KChIP4.1 have different effects on their molecular structure.
15578212 Co-expression of SGK1, but not of SGK2 or SGK3, increased Kv 4.3/KChIP2b channel currents. [KChIP2b; AH010566]

Patents:

Patents logo
US Patent No.Title
7547687 Therapeutic treatment methods
7482334 Therapeutic treatment methods
7276206 Electrical field stimulation of eukaryotic cells

KCNIP2 results (if any) from reagent suppliers

Google CSE Logo
KCNIP2 monoclonal antibody (M01)
KCNIP2 (AAH34685, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. ... Western blot analysis of KCNIP2 over-expressed 293 cell line, ...
http://www.abgent.com/products/catalog_no/AT2597a_KCNIP2_mon...

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DREAM (K-17) Antibody sc-9309
Mouse, Kcnip2, 80906, 19 C3, Q9JJ69, N/A. Ordering Information. Product Name, Catalog #, Unit, Price, Qty, Wish List. DREAM (K-17), sc-9309, 200 µg/ml, $259
...
http://www.scbt.com/datasheet-9309-dream-k-17-antibody.html...

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Abgent - Cell and Structure Antibodies - Cell_structure
AP7902a, JIK Antibody (C-term), WB, E, H. AT2597a, KCNIP2 monoclonal antibody ( M01), ELISA,IHC-P,RNAi-Ab,WB-Re,WB-Tr, H. AP7466bNEW, KIF3C Antibody (C-term)
...
http://www.abgent.com/products/category/cell_function/cell_s...

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KChIP2 (9K9) Antibody sc-134371
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, KCNIP2, 30819, 10q24.32, Q9NS61 ...
http://www.scbt.com/datasheet-134371-kchip2-9k9-antibody.htm...

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KChIP2c Antibody (N-term Y20)
... channel modulatory protein 2; Potassium channel-interacting protein 2; Cardiac voltage-gated potassium channel modulatory subunit; KCNIP2; KCHIP2; ...
http://www.abgent.com/products/catalog_no/AP1573d...

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3C-3E
Monoclonal Anti-KCNIP2 antibody produced in mouse clone 3E7, purified immunoglobulin, buffered aqueous solution, 3E7 (monoclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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Mouse KChIP2 Antibody (C-term)
Potassium channel interacting protein 2; Kcnip2;. Application Data: Calculated MW: 29012 Da. This product is offered at a low price as part of the Abgent ...
http://www.abgent.com/products/catalog_no/AP1573f...

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